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PLCB2 PLCB2 IL6 IL6 RAB7B RAB7B IL10 IL10 PIK3R3 PIK3R3 IL1R2 IL1R2 PRDX1 PRDX1 LAMB3 LAMB3 ITGAM ITGAM PRKCA PRKCA TGFB2 TGFB2 PLCB1 PLCB1 CASP3 CASP3 COL4A2 COL4A2 LOC100619446 LOC100619446 LOC100025102 LOC100025102 F7BXY2_MONDO F7BXY2_MONDO TGFB3 TGFB3 LAMC1 LAMC1 LAMC2 LAMC2 RAB7A RAB7A TGFB1 TGFB1 RELA RELA COL3A1 COL3A1 IL12A IL12A COL1A1 COL1A1 GNA14 GNA14 GNAQ GNAQ HSPB1 HSPB1 IL1B IL1B LAMB1 LAMB1 C8G C8G ARG1 ARG1 LAMA4 LAMA4 GNA11 GNA11 GNA15 GNA15 CXCL8 CXCL8 TLR4 TLR4 PIK3R1 PIK3R1 C9 C9 NFKB1 NFKB1 COL4A3 COL4A3 PIK3CA PIK3CA GNAL GNAL NOS2 NOS2 CD14 CD14 LAMA3 LAMA3 TLR2 TLR2 COL4A1 COL4A1 K7DYV5_MONDO K7DYV5_MONDO LAMA2 LAMA2 LAMB2 LAMB2 RAB5A RAB5A LAMA1 LAMA1 ITGB2 ITGB2 PRKCB PRKCB ADCY1 ADCY1 LOC654275 LOC654275 FN1 FN1 VCL VCL PLCB4 PLCB4 PRKACA PRKACA PTK2 PTK2 ACTN4 ACTN4 PIK3CB PIK3CB IL1R1 IL1R1 C8A C8A ITGAM-2 ITGAM-2 RAB5C RAB5C ENSMODP00000059741 ENSMODP00000059741 GNAS GNAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa)
IL6Uncharacterized protein. (220 aa)
RAB7BRAB7B, member RAS oncogene family. (200 aa)
IL10Interleukin 10. (173 aa)
PIK3R3SH2 domain-containing protein. (276 aa)
IL1R2Uncharacterized protein. (414 aa)
PRDX1Thioredoxin domain-containing protein. (225 aa)
LAMB3Laminin subunit beta 3. (1171 aa)
ITGAMIntegrin subunit alpha M; Belongs to the integrin alpha chain family. (1076 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (689 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1117 aa)
CASP3Caspase-3-like protein 1; Belongs to the peptidase C14A family. (276 aa)
COL4A2Collagen type IV alpha 2 chain. (1455 aa)
LOC100619446SERPIN domain-containing protein; Belongs to the serpin family. (406 aa)
LOC100025102SERPIN domain-containing protein; Belongs to the serpin family. (429 aa)
F7BXY2_MONDOSERPIN domain-containing protein; Belongs to the serpin family. (243 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
LAMC1Laminin subunit gamma 1. (1486 aa)
LAMC2Laminin subunit gamma 2. (1191 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (424 aa)
RELARELA proto-oncogene, NF-kB subunit. (543 aa)
COL3A1Collagen type III alpha 1 chain. (1461 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (204 aa)
COL1A1Collagen type I alpha 1 chain. (1430 aa)
GNA14G protein subunit alpha 14. (355 aa)
GNAQG protein subunit alpha q. (359 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (256 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (272 aa)
LAMB1Laminin subunit beta 1. (1786 aa)
C8GComplement C8 gamma chain; Belongs to the calycin superfamily. Lipocalin family. (202 aa)
ARG1Arginase. (317 aa)
LAMA4Laminin subunit alpha 4. (1677 aa)
GNA11G protein subunit alpha 11. (359 aa)
GNA15G protein subunit alpha 15. (374 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (731 aa)
C9Complement C9. (620 aa)
NFKB1Nuclear factor kappa B subunit 1. (995 aa)
COL4A3Collagen type IV alpha 3 chain. (1607 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
GNALG protein subunit alpha L. (379 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1146 aa)
CD14Uncharacterized protein. (382 aa)
LAMA3Laminin subunit alpha 3. (3340 aa)
TLR2Toll like receptor 2; Belongs to the Toll-like receptor family. (785 aa)
COL4A1Collagen type IV alpha 1 chain. (1586 aa)
K7DYV5_MONDOIg-like domain-containing protein. (295 aa)
LAMA2Laminin subunit alpha 2. (3063 aa)
LAMB2Laminin subunit beta 2. (1807 aa)
RAB5ARAB5A, member RAS oncogene family. (224 aa)
LAMA1Laminin subunit alpha 1. (2951 aa)
ITGB2Integrin beta. (792 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (641 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1131 aa)
LOC654275Caspase-3-like protein 2; Belongs to the peptidase C14A family. (276 aa)
FN1Fibronectin 1. (2482 aa)
VCLVinculin. (1147 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1182 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa)
PTK2Uncharacterized protein. (161 aa)
ACTN4Actinin alpha 4. (934 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1074 aa)
IL1R1TIR domain-containing protein. (344 aa)
C8AComplement C8 alpha chain. (580 aa)
ITGAM-2VWFA domain-containing protein; Belongs to the integrin alpha chain family. (1177 aa)
RAB5CUncharacterized protein. (216 aa)
ENSMODP00000059741Uncharacterized protein. (70 aa)
GNASUncharacterized protein. (370 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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