STRINGSTRING
EIF2AK4 EIF2AK4 IL2RB IL2RB JAK1 JAK1 IL6 IL6 CBLB CBLB IKBKE IKBKE PIK3R3 PIK3R3 LOC100028903 LOC100028903 JUN JUN IFN3 IFN3 LOC100021419 LOC100021419 RACK1 RACK1 EIF3H EIF3H CASP3 CASP3 IL2RG IL2RG TYK2 TYK2 HSPA1A HSPA1A FOS FOS TRADD TRADD AKT3 AKT3 CCNE2 CCNE2 AKT2 AKT2 EIF2AK1 EIF2AK1 IKBKG IKBKG RELA RELA EIF2AK3 EIF2AK3 EIF2S1 EIF2S1 IKBKB IKBKB CHUK CHUK IL12A IL12A RAB9B RAB9B STAT1 STAT1 TRAF3 TRAF3 NFKBIB NFKBIB CD3G CD3G CD3D CD3D IRF3 IRF3 AKT1 AKT1 IL1B IL1B BAK1 BAK1 LOC100011470 LOC100011470 LOC100012174 LOC100012174 CD209 CD209 CASP8 CASP8 ADAR ADAR TNFAIP3 TNFAIP3 CDKN1B CDKN1B CCND2 CCND2 IRAK4 IRAK4 BCL2L1 BCL2L1 CSNK2A1 CSNK2A1 TLR4 TLR4 PIK3R1 PIK3R1 TRAF6 TRAF6 NFKB1 NFKB1 MAPK10 MAPK10 PIK3CA PIK3CA EIF2AK2 EIF2AK2 MAPK9 MAPK9 IRF9 IRF9 CD28 CD28 TLR2 TLR2 LOC100011711 LOC100011711 LOC100015032 LOC100015032 LOC100021467 LOC100021467 LOC100021258 LOC100021258 RAB9A RAB9A MSN MSN CASP18 CASP18 LOC100026811 LOC100026811 LOC103094472 LOC103094472 BBC3 BBC3 CSNK2A2 CSNK2A2 BAD BAD ENSMODP00000044636 ENSMODP00000044636 IFIH1 IFIH1 OAS3 OAS3 IFNAR2 IFNAR2 CD3E CD3E LOC654275 LOC654275 MAP3K7 MAP3K7 IFN7 IFN7 BAX BAX CDK6 CDK6 CCND1 CCND1 LOC100015202 LOC100015202 TLR9 TLR9 CCND3 CCND3 CSNK2B CSNK2B IL2 IL2 STAT3 STAT3 PIK3CB PIK3CB MAVS MAVS TAB2 TAB2 NFKBIA NFKBIA HSPA8 HSPA8 IFN4 IFN4 LOC100021368 LOC100021368 F7BIP4_MONDO F7BIP4_MONDO CCNE1 CCNE1 CYCS CYCS IFN2 IFN2 FADD FADD GSK3B GSK3B APAF1 APAF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1663 aa)
IL2RBFibronectin type-III domain-containing protein. (562 aa)
JAK1Protein kinase domain-containing protein. (199 aa)
IL6Uncharacterized protein. (220 aa)
CBLBCbl proto-oncogene B. (983 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (726 aa)
PIK3R3SH2 domain-containing protein. (276 aa)
LOC10002890325A_SYNTH_3 domain-containing protein. (397 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (344 aa)
IFN3Uncharacterized protein. (184 aa)
LOC100021419Type I interferon 5. (184 aa)
RACK1Receptor for activated C kinase 1. (317 aa)
EIF3HEukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (353 aa)
CASP3Caspase-3-like protein 1; Belongs to the peptidase C14A family. (276 aa)
IL2RGFibronectin type-III domain-containing protein. (301 aa)
TYK2Tyrosine-protein kinase. (1193 aa)
HSPA1AUncharacterized protein; Belongs to the heat shock protein 70 family. (722 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (379 aa)
TRADDTNFRSF1A associated via death domain. (361 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
CCNE2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (405 aa)
AKT2AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (498 aa)
EIF2AK1Eukaryotic translation initiation factor 2 alpha kinase 1. (630 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (547 aa)
RELARELA proto-oncogene, NF-kB subunit. (543 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1104 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (693 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (204 aa)
RAB9BRAB9B, member RAS oncogene family. (201 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)
NFKBIBNFKB inhibitor beta. (314 aa)
CD3GCD3g molecule. (180 aa)
CD3DIg_4 domain-containing protein. (272 aa)
IRF3IRF tryptophan pentad repeat domain-containing protein. (409 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (272 aa)
BAK1BCL2 antagonist/killer 1. (204 aa)
LOC100011470Signal transducer and activator of transcription. (839 aa)
LOC100012174Signal transducer and activator of transcription. (782 aa)
CD209C-type lectin domain-containing protein. (349 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (472 aa)
ADARAdenosine deaminase RNA specific. (1143 aa)
TNFAIP3TNF alpha induced protein 3. (796 aa)
CDKN1BP27 protein. (199 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (290 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (458 aa)
BCL2L1BCL2 like 1. (227 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (448 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (731 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (540 aa)
NFKB1Nuclear factor kappa B subunit 1. (995 aa)
MAPK10Mitogen-activated protein kinase. (464 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
EIF2AK2Uncharacterized protein. (651 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
IRF9Interferon regulatory factor 9. (425 aa)
CD28CD28 molecule. (221 aa)
TLR2Toll like receptor 2; Belongs to the Toll-like receptor family. (785 aa)
LOC100011711Uncharacterized protein; Belongs to the heat shock protein 70 family. (644 aa)
LOC100015032Uncharacterized protein; Belongs to the heat shock protein 70 family. (644 aa)
LOC100021467Uncharacterized protein. (183 aa)
LOC100021258Type I interferon 1. (198 aa)
RAB9ARAB9A, member RAS oncogene family. (278 aa)
MSNMoesin. (574 aa)
CASP18Uncharacterized protein; Belongs to the peptidase C14A family. (471 aa)
LOC100026811Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
LOC103094472Uncharacterized protein. (450 aa)
BBC3Uncharacterized protein. (318 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (392 aa)
BADUncharacterized protein. (212 aa)
ENSMODP0000004463625A_SYNTH_3 domain-containing protein. (298 aa)
IFIH1Interferon induced with helicase C domain 1. (1021 aa)
OAS32'-5'-oligoadenylate synthetase 3. (1115 aa)
IFNAR2Uncharacterized protein. (511 aa)
CD3EIGc2 domain-containing protein. (252 aa)
LOC654275Caspase-3-like protein 2; Belongs to the peptidase C14A family. (276 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (607 aa)
IFN7Type I interferon 7. (183 aa)
BAXUncharacterized protein. (296 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (390 aa)
CCND1Uncharacterized protein. (67 aa)
LOC100015202Ig-like domain-containing protein. (321 aa)
TLR9TIR domain-containing protein. (1063 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (300 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (235 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (142 aa)
STAT3Signal transducer and activator of transcription. (805 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1074 aa)
MAVSCARD_2 domain-containing protein. (478 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (696 aa)
NFKBIAANK_REP_REGION domain-containing protein. (400 aa)
HSPA8Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (648 aa)
IFN4Type I interferon 4. (183 aa)
LOC100021368Uncharacterized protein. (183 aa)
F7BIP4_MONDOIg-like domain-containing protein. (182 aa)
CCNE1Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (732 aa)
CYCSCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
IFN2Type I interferon 2. (183 aa)
FADDUncharacterized protein. (193 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (444 aa)
APAF1Apoptotic peptidase activating factor 1. (1279 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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