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| | GNA12 | G protein subunit alpha 12. (380 aa) |
| | SRC | Tyrosine-protein kinase. (550 aa) |
| | PLCB2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1188 aa) |
| | RAC2 | Rac family small GTPase 2. (281 aa) |
| | GNG12 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | CREB3L3 | cAMP responsive element binding protein 3 like 3. (508 aa) |
| | F7F7P9_MONDO | Uncharacterized protein. (359 aa) |
| | JAK1 | Protein kinase domain-containing protein. (199 aa) |
| | IL6 | Uncharacterized protein. (220 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1254 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (435 aa) |
| | GNB5 | G protein subunit beta 5. (353 aa) |
| | GNAI3 | G protein subunit alpha i3. (399 aa) |
| | ADCY2 | Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1104 aa) |
| | PIK3R3 | SH2 domain-containing protein. (276 aa) |
| | CALM1 | Calmodulin 1; Belongs to the calmodulin family. (149 aa) |
| | TRAF5 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (560 aa) |
| | E2F1 | E2F transcription factor 1. (443 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (902 aa) |
| | ADCY4 | Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1109 aa) |
| | LOC103105351 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (352 aa) |
| | RAC3 | Rac family small GTPase 3. (192 aa) |
| | IFN3 | Uncharacterized protein. (184 aa) |
| | LOC100021419 | Type I interferon 5. (184 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (689 aa) |
| | GNA13 | G protein subunit alpha 13. (377 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1117 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2733 aa) |
| | CASP3 | Caspase-3-like protein 1; Belongs to the peptidase C14A family. (276 aa) |
| | GNG10 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | TRADD | TNFRSF1A associated via death domain. (361 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (666 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (523 aa) |
| | GNB1 | G protein subunit beta 1. (340 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (484 aa) |
| | CREB3 | BZIP domain-containing protein. (370 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (476 aa) |
| | AKT2 | AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (498 aa) |
| | GNG3 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (706 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1304 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1213 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (547 aa) |
| | GNG8 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa) |
| | ATF4 | Activating transcription factor 4. (346 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (517 aa) |
| | CALML4 | Calmodulin like 4. (156 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (543 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | CXCL12 | SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family. (89 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (693 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa) |
| | LOC100026571 | Uncharacterized protein. (584 aa) |
| | ITGAV | Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1058 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (784 aa) |
| | RB1 | RB transcriptional corepressor 1. (937 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | LOC103092123 | MHC class I antigen. (355 aa) |
| | E2F3 | E2F transcription factor 3. (457 aa) |
| | Modo-UT10 | MHC class I antigen. (335 aa) |
| | LOC103094634 | Ig-like domain-containing protein. (333 aa) |
| | CCR1 | C-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (363 aa) |
| | F6W0U8_MONDO | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (361 aa) |
| | CALR | Calreticulin. (418 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (608 aa) |
| | STING1 | Transmembrane protein 173. (381 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1328 aa) |
| | TSC1 | TSC complex subunit 1. (1152 aa) |
| | E2F2 | E2F transcription factor 2. (377 aa) |
| | GNAQ | G protein subunit alpha q. (359 aa) |
| | ADCY7 | Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1085 aa) |
| | ARHGEF12 | Rho guanine nucleotide exchange factor 12. (1539 aa) |
| | CX3CL1 | SCY domain-containing protein. (409 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | IL10RA | Fibronectin type-III domain-containing protein. (605 aa) |
| | IRF3 | IRF tryptophan pentad repeat domain-containing protein. (409 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (366 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (272 aa) |
| | CREB3L2 | cAMP responsive element binding protein 3 like 2. (518 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (204 aa) |
| | TAP1 | Transporter 1, ATP binding cassette subfamily B member. (737 aa) |
| | PTGER2 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (347 aa) |
| | MODO-UE | Ig-like domain-containing protein; Belongs to the MHC class I family. (355 aa) |
| | ATF6B | Activating transcription factor 6 beta. (708 aa) |
| | CASP8 | Caspase 8; Belongs to the peptidase C14A family. (472 aa) |
| | CREB5 | Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (504 aa) |
| | LOC100012302 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (362 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) |
| | ADCY3 | Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1145 aa) |
| | TSC2 | TSC complex subunit 2. (1830 aa) |
| | ADCY9 | Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1359 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2698 aa) |
| | ARHGEF11 | Rho guanine nucleotide exchange factor 11. (1552 aa) |
| | GNG13 | G protein subunit gamma 13. (67 aa) |
| | GNAI1 | G protein subunit alpha i1. (354 aa) |
| | CREB3L4 | cAMP responsive element binding protein 3 like 4. (360 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (633 aa) |
| | CRKL | Uncharacterized protein. (303 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa) |
| | PDIA3 | Protein disulfide-isomerase. (506 aa) |
| | TNFRSF1A | Uncharacterized protein. (453 aa) |
| | GNB3 | G protein subunit beta 3. (340 aa) |
| | CGAS | Cyclic GMP-AMP synthase. (518 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (445 aa) |
| | F7FNN8_MONDO | Uncharacterized protein. (199 aa) |
| | LOC103099606 | C-C motif chemokine. (95 aa) |
| | LOC100020842 | C-C motif chemokine. (156 aa) |
| | CCL5 | C-C motif chemokine ligand 5. (91 aa) |
| | GNA11 | G protein subunit alpha 11. (359 aa) |
| | LOC103093665 | C-C motif chemokine. (226 aa) |
| | CXCL8 | Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (731 aa) |
| | PTGER4 | Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (521 aa) |
| | PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1085 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (995 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (521 aa) |
| | IL10RB | Interleukin 10 receptor subunit beta. (330 aa) |
| | GNB4 | G protein subunit beta 4. (340 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | F7D7P9_MONDO | Uncharacterized protein; Belongs to the calmodulin family. (65 aa) |
| | CCR3 | C-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (356 aa) |
| | IL6R | Interleukin-6 receptor alpha. (467 aa) |
| | AKAP13 | Uncharacterized protein. (1424 aa) |
| | CALML3 | Calmodulin like 3; Belongs to the calmodulin family. (149 aa) |
| | LOC100021467 | Uncharacterized protein. (183 aa) |
| | LOC100021258 | Type I interferon 1. (198 aa) |
| | PTGER3 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (363 aa) |
| | KRAS-2 | GTPase KRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304- dependent manner (By similarity); Belongs to the small GTPase superfamily. Ras family. (194 aa) |
| | GNG7 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa) |
| | LOC100017283 | C-C motif chemokine. (91 aa) |
| | LOC100017328 | C-C motif chemokine. (95 aa) |
| | CASP18 | Uncharacterized protein; Belongs to the peptidase C14A family. (471 aa) |
| | GNG4 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa) |
| | LOC100026811 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa) |
| | CDKN2A | Tumor suppressor ARF; Capable of inducing cell cycle arrest in G1 and G2 phases. Acts as a tumor suppressor. Binds to MDM2 and blocks its nucleocytoplasmic shuttling by sequestering it in the nucleolus. This inhibits the oncogenic action of MDM2 by blocking MDM2-induced degradation of p53 and enhancing p53-dependent transactivation and apoptosis. Also induces G2 arrest and apoptosis in a p53-independent manner by preventing the activation of cyclin B1/CDC2 complexes. Binds to BCL6 and down-regulates BCL6-induced transcriptional repression. Binds to E2F1 and MYC and blocks their transcr [...] (185 aa) |
| | GNAI2 | G protein subunit alpha i2. (315 aa) |
| | NFATC3 | Nuclear factor of activated T cells 3. (1079 aa) |
| | Modo-UT15 | Ig-like domain-containing protein. (362 aa) |
| | ENSMODP00000043772 | MHC_I-like_Ag-recog domain-containing protein. (212 aa) |
| | CREB3L1 | cAMP responsive element binding protein 3 like 1. (535 aa) |
| | ENSMODP00000045298 | MHC_I-like_Ag-recog domain-containing protein; Belongs to the MHC class I family. (250 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (520 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (641 aa) |
| | CXCR4 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (375 aa) |
| | ADCY1 | Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1131 aa) |
| | LOC654275 | Caspase-3-like protein 2; Belongs to the peptidase C14A family. (276 aa) |
| | NFATC1 | Nuclear factor of activated T cells 1. (950 aa) |
| | GNGT2 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | IFN7 | Type I interferon 7. (183 aa) |
| | MODO-UK | Ig-like domain-containing protein; Belongs to the MHC class I family. (414 aa) |
| | NRAS | GTPase NRas. (195 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1182 aa) |
| | ENSMODP00000048581 | Ig-like domain-containing protein. (339 aa) |
| | PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa) |
| | PTGER1 | Prostaglandin E receptor 1. (450 aa) |
| | BAX | Uncharacterized protein. (296 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (390 aa) |
| | CCND1 | Uncharacterized protein. (67 aa) |
| | ENSMODP00000049121 | Uncharacterized protein. (567 aa) |
| | LOC100026215 | Uncharacterized protein. (722 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (927 aa) |
| | GNG5 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa) |
| | STAT3 | Signal transducer and activator of transcription. (805 aa) |
| | PTK2 | Uncharacterized protein. (161 aa) |
| | EIF4EBP1 | Uncharacterized protein. (273 aa) |
| | B2M | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity). (122 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1074 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (364 aa) |
| | MODO-UJ | Ig-like domain-containing protein; Belongs to the MHC class I family. (381 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2608 aa) |
| | IL1R1 | TIR domain-containing protein. (344 aa) |
| | MODO-UG | Ig-like domain-containing protein. (235 aa) |
| | NFKBIA | ANK_REP_REGION domain-containing protein. (400 aa) |
| | IFN4 | Type I interferon 4. (183 aa) |
| | LOC100021368 | Uncharacterized protein. (183 aa) |
| | LOC100010184 | Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa) |
| | ROCK1 | Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1322 aa) |
| | SIRT6 | Uncharacterized protein. (547 aa) |
| | LOC100030002 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (352 aa) |
| | RHEB | Ras homolog, mTORC1 binding. (184 aa) |
| | LOC100024719 | Ig-like domain-containing protein; Belongs to the MHC class I family. (441 aa) |
| | MODO-UB | Ig-like domain-containing protein; Belongs to the MHC class I family. (376 aa) |
| | RHOA | Uncharacterized protein. (193 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR. (1040 aa) |
| | LOC103106351 | MHC class I antigen. (357 aa) |
| | CYCS | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | Modo-UA | Ig-like domain-containing protein; Belongs to the MHC class I family. (389 aa) |
| | GNB2 | G protein subunit beta 2. (367 aa) |
| | LOC107651418 | Ig-like domain-containing protein. (232 aa) |
| | IFN2 | Type I interferon 2. (183 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (327 aa) |
| | FADD | Uncharacterized protein. (193 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (444 aa) |
| | MHC-I | Ig-like domain-containing protein; Belongs to the MHC class I family. (376 aa) |
| | ENSMODP00000059741 | Uncharacterized protein. (70 aa) |
| | GNAS | Uncharacterized protein. (370 aa) |
| | HRAS | GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (189 aa) |
| | ROCK2 | Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1482 aa) |
