STRINGSTRING
LOC100010059 LOC100010059 LOC100010000 LOC100010000 LOC100010619 LOC100010619 LOC100010951 LOC100010951 F7A744_MONDO F7A744_MONDO TICAM1 TICAM1 KPNA7 KPNA7 JAK1 JAK1 IL6 IL6 CPSF4 CPSF4 SOCS3 SOCS3 IKBKE IKBKE PIK3R3 PIK3R3 LOC100010487 LOC100010487 XPO1 XPO1 LOC100028903 LOC100028903 IFN3 IFN3 LOC100021419 LOC100021419 PABPN1L PABPN1L KPNA2 KPNA2 PRKCA PRKCA CASP3 CASP3 SLC25A4 SLC25A4 TLR3 TLR3 CIITA CIITA TYK2 TYK2 TRADD TRADD RAF1 RAF1 AKT3 AKT3 RNASEL RNASEL AKT2 AKT2 NXF1 NXF1 NUP98 NUP98 DNAJC3 DNAJC3 IKBKG IKBKG LOC103100524 LOC103100524 RELA RELA MAP2K1 MAP2K1 RAB11A RAB11A EIF2S1 EIF2S1 IKBKB IKBKB CHUK CHUK IL12A IL12A STAT1 STAT1 LOC100028958 LOC100028958 SLC25A31 SLC25A31 NLRX1 NLRX1 TRAF3 TRAF3 NFKBIB NFKBIB LOC100031528 LOC100031528 IRF3 IRF3 AKT1 AKT1 IL1B IL1B BAK1 BAK1 VDAC1 VDAC1 LOC100026858 LOC100026858 LOC100026112 LOC100026112 LOC100026007 LOC100026007 TRIM25 TRIM25 CASP8 CASP8 JAK2 JAK2 MAPK3 MAPK3 CREBBP CREBBP RAE1 RAE1 ADAR ADAR KPNA6 KPNA6 MAPK1 MAPK1 TNFRSF1A TNFRSF1A KPNA1 KPNA1 IRAK4 IRAK4 LOC100021214 LOC100021214 CCL5 CCL5 LOC103093665 LOC103093665 CXCL8 CXCL8 TLR4 TLR4 PIK3R1 PIK3R1 NFKB1 NFKB1 TMPRSS11D TMPRSS11D TMPRSS2 TMPRSS2 IFNGR2 IFNGR2 PIK3CA PIK3CA LOC100028638 LOC100028638 LOC100016601 LOC100016601 EIF2AK2 EIF2AK2 F7G5T5_MONDO F7G5T5_MONDO LOC100032592 LOC100032592 PRSS37 PRSS37 IRF9 IRF9 LOC100018337 LOC100018337 LOC100020439 LOC100020439 LOC100021467 LOC100021467 LOC100021258 LOC100021258 PYCARD PYCARD PML PML EP300 EP300 CPSF4L CPSF4L LOC100025909 LOC100025909 CASP18 CASP18 LOC100026811 LOC100026811 RSAD2 RSAD2 LOC100025932 LOC100025932 ENSMODP00000044636 ENSMODP00000044636 IFIH1 IFIH1 ENSMODP00000045162 ENSMODP00000045162 ACTG1 ACTG1 PRKCB PRKCB HLA-DRA HLA-DRA OAS3 OAS3 IFNAR2 IFNAR2 LOC654275 LOC654275 ENSMODP00000047908 ENSMODP00000047908 RAB11B RAB11B IFN7 IFN7 BAX BAX CDK6 CDK6 LOC103102395 LOC103102395 CCND3 CCND3 DNAJB1 DNAJB1 PIK3CB PIK3CB MAVS MAVS TNFSF10 TNFSF10 NFKBIA NFKBIA IFN4 IFN4 LOC100021368 LOC100021368 SIRT6 SIRT6 PLG PLG IFNGR1 IFNGR1 CALCOCO2 CALCOCO2 CYCS CYCS BCL2L2-PABPN1 BCL2L2-PABPN1 NXT2 NXT2 LOC103101367 LOC103101367 LOC100026891 LOC100026891 IFN2 IFN2 FADD FADD APAF1 APAF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100010059Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (247 aa)
LOC100010000Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (247 aa)
LOC100010619Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (243 aa)
LOC100010951Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (246 aa)
F7A744_MONDOPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (227 aa)
TICAM1TRIF-NTD domain-containing protein. (713 aa)
KPNA7Importin subunit alpha; Functions in nuclear protein import. (516 aa)
JAK1Protein kinase domain-containing protein. (199 aa)
IL6Uncharacterized protein. (220 aa)
CPSF4Cleavage and polyadenylation specific factor 4. (269 aa)
SOCS3Suppressor of cytokine signaling 3. (235 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (726 aa)
PIK3R3SH2 domain-containing protein. (276 aa)
LOC100010487Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
XPO1Exportin 1. (1071 aa)
LOC10002890325A_SYNTH_3 domain-containing protein. (397 aa)
IFN3Uncharacterized protein. (184 aa)
LOC100021419Type I interferon 5. (184 aa)
PABPN1LRRM domain-containing protein. (302 aa)
KPNA2Importin subunit alpha; Functions in nuclear protein import. (528 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (689 aa)
CASP3Caspase-3-like protein 1; Belongs to the peptidase C14A family. (276 aa)
SLC25A4Solute carrier family 25 member 4; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (905 aa)
CIITAClass II major histocompatibility complex transactivator. (1121 aa)
TYK2Tyrosine-protein kinase. (1193 aa)
TRADDTNFRSF1A associated via death domain. (361 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (666 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
RNASELUncharacterized protein. (764 aa)
AKT2AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (498 aa)
NXF1Uncharacterized protein. (624 aa)
NUP98Nucleoporin 98. (1816 aa)
DNAJC3DnaJ heat shock protein family (Hsp40) member C3. (504 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (547 aa)
LOC103100524Uncharacterized protein. (408 aa)
RELARELA proto-oncogene, NF-kB subunit. (543 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
RAB11ARAB11A, member RAS oncogene family. (269 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (693 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (204 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
LOC100028958Uncharacterized protein. (375 aa)
SLC25A31Solute carrier family 25 member 31; Belongs to the mitochondrial carrier (TC 2.A.29) family. (314 aa)
NLRX1NLR family member X1. (975 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)
NFKBIBNFKB inhibitor beta. (314 aa)
LOC100031528Uncharacterized protein; Belongs to the peptidase S1 family. (418 aa)
IRF3IRF tryptophan pentad repeat domain-containing protein. (409 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (272 aa)
BAK1BCL2 antagonist/killer 1. (204 aa)
VDAC1Voltage dependent anion channel 1. (400 aa)
LOC100026858Ig-like domain-containing protein. (262 aa)
LOC100026112Ig-like domain-containing protein; Belongs to the MHC class II family. (256 aa)
LOC100026007Ig-like domain-containing protein; Belongs to the MHC class II family. (256 aa)
TRIM25Tripartite motif containing 25. (672 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (472 aa)
JAK2Tyrosine-protein kinase. (1130 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
CREBBPCREB binding protein. (2456 aa)
RAE1Ribonucleic acid export 1. (368 aa)
ADARAdenosine deaminase RNA specific. (1143 aa)
KPNA6Importin subunit alpha; Functions in nuclear protein import. (541 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa)
TNFRSF1AUncharacterized protein. (453 aa)
KPNA1Importin subunit alpha; Functions in nuclear protein import. (541 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (458 aa)
LOC100021214Uncharacterized protein. (248 aa)
CCL5C-C motif chemokine ligand 5. (91 aa)
LOC103093665C-C motif chemokine. (226 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (838 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (731 aa)
NFKB1Nuclear factor kappa B subunit 1. (995 aa)
TMPRSS11DTransmembrane serine protease 11D; Belongs to the peptidase S1 family. (419 aa)
TMPRSS2Transmembrane serine protease 2; Belongs to the peptidase S1 family. (487 aa)
IFNGR2Uncharacterized protein. (344 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC100028638NTF2 domain-containing protein. (137 aa)
LOC100016601Uncharacterized protein. (374 aa)
EIF2AK2Uncharacterized protein. (651 aa)
F7G5T5_MONDOUncharacterized protein; Belongs to the peptidase C14A family. (284 aa)
LOC100032592Uncharacterized protein; Belongs to the peptidase C14A family. (375 aa)
PRSS37Peptidase S1 domain-containing protein. (235 aa)
IRF9Interferon regulatory factor 9. (425 aa)
LOC100018337Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. (298 aa)
LOC100020439Uncharacterized protein; Belongs to the actin family. (374 aa)
LOC100021467Uncharacterized protein. (183 aa)
LOC100021258Type I interferon 1. (198 aa)
PYCARDPYD and CARD domain containing. (195 aa)
PMLUncharacterized protein. (1118 aa)
EP300E1A binding protein p300. (2454 aa)
CPSF4LUncharacterized protein. (166 aa)
LOC100025909Ig-like domain-containing protein. (282 aa)
CASP18Uncharacterized protein; Belongs to the peptidase C14A family. (471 aa)
LOC100026811Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
RSAD2Radical S-adenosyl methionine domain containing 2. (267 aa)
LOC100025932Ig-like domain-containing protein; Belongs to the MHC class II family. (264 aa)
ENSMODP0000004463625A_SYNTH_3 domain-containing protein. (298 aa)
IFIH1Interferon induced with helicase C domain 1. (1021 aa)
ENSMODP00000045162Ig-like domain-containing protein; Belongs to the MHC class II family. (276 aa)
ACTG1Uncharacterized protein. (375 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (641 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (287 aa)
OAS32'-5'-oligoadenylate synthetase 3. (1115 aa)
IFNAR2Uncharacterized protein. (511 aa)
LOC654275Caspase-3-like protein 2; Belongs to the peptidase C14A family. (276 aa)
ENSMODP00000047908Ig-like domain-containing protein; Belongs to the MHC class II family. (267 aa)
RAB11BUncharacterized protein. (220 aa)
IFN7Type I interferon 7. (183 aa)
BAXUncharacterized protein. (296 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (390 aa)
LOC103102395Uncharacterized protein. (207 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (300 aa)
DNAJB1DnaJ heat shock protein family (Hsp40) member B1. (340 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1074 aa)
MAVSCARD_2 domain-containing protein. (478 aa)
TNFSF10Tumor necrosis factor ligand superfamily member. (301 aa)
NFKBIAANK_REP_REGION domain-containing protein. (400 aa)
IFN4Type I interferon 4. (183 aa)
LOC100021368Uncharacterized protein. (183 aa)
SIRT6Uncharacterized protein. (547 aa)
PLGPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (817 aa)
IFNGR1Fibronectin type-III domain-containing protein. (503 aa)
CALCOCO2Zn-C2H2_12 domain-containing protein. (200 aa)
CYCSCytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa)
BCL2L2-PABPN1Uncharacterized protein. (333 aa)
NXT2NTF2 domain-containing protein. (201 aa)
LOC103101367Uncharacterized protein. (211 aa)
LOC100026891Ig-like domain-containing protein. (270 aa)
IFN2Type I interferon 2. (183 aa)
FADDUncharacterized protein. (193 aa)
APAF1Apoptotic peptidase activating factor 1. (1279 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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