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| | SRC | Tyrosine-protein kinase. (550 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1292 aa) |
| | WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (398 aa) |
| | TWIST1 | Twist family bHLH transcription factor 1. (189 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (435 aa) |
| | PIK3R3 | SH2 domain-containing protein. (276 aa) |
| | IGF1 | Insulin like growth factor 1. (225 aa) |
| | PTCH1 | Patched 1. (1521 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (599 aa) |
| | DDX5 | Uncharacterized protein; Belongs to the DEAD box helicase family. (614 aa) |
| | RPS6 | 40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (249 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (540 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (689 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa) |
| | ITPR1 | Inositol 1,4,5-trisphosphate receptor type 1. (2733 aa) |
| | CASP3 | Caspase-3-like protein 1; Belongs to the peptidase C14A family. (276 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (480 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (545 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (287 aa) |
| | FZD6 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa) |
| | PLCE1 | Phosphoinositide phospholipase C. (2291 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (666 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa) |
| | FZD8 | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (710 aa) |
| | RPS6KB1 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (523 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (484 aa) |
| | WNT7B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (217 aa) |
| | RPS6KB2 | Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (476 aa) |
| | AKT2 | AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (498 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (424 aa) |
| | WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (200 aa) |
| | FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa) |
| | HIF1A | Hypoxia inducible factor 1 subunit alpha. (830 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1304 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1213 aa) |
| | HOXD10 | Homeobox D10. (340 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | DCN | Decorin; May affect the rate of fibrils formation. (356 aa) |
| | LUM | Lumican. (341 aa) |
| | MAP2K1 | Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa) |
| | PDCD4 | Programmed cell death 4. (469 aa) |
| | FZD1 | Frizzled class receptor 1; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (809 aa) |
| | ITGAV | Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1058 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (784 aa) |
| | CTNNB1 | Catenin beta 1. (781 aa) |
| | FZD2 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (571 aa) |
| | HBEGF | Heparin binding EGF like growth factor. (208 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1328 aa) |
| | COL1A1 | Collagen type I alpha 1 chain. (1430 aa) |
| | LOC100028958 | Uncharacterized protein. (375 aa) |
| | ARHGEF12 | Rho guanine nucleotide exchange factor 12. (1539 aa) |
| | MMP2 | Matrix metallopeptidase 2. (688 aa) |
| | CBL | Cbl proto-oncogene. (837 aa) |
| | GPC1 | Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (550 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (366 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | MMP9 | Matrix metallopeptidase 9. (709 aa) |
| | FZD9 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (560 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (341 aa) |
| | SLC9A1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (392 aa) |
| | HSPB2 | SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (182 aa) |
| | RDX | Radixin. (598 aa) |
| | SMO | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (785 aa) |
| | FLNC | Filamin C. (2653 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1264 aa) |
| | GPC3 | Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (486 aa) |
| | IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa) |
| | WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (375 aa) |
| | PPP1CB | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa) |
| | ERBB4 | Receptor protein-tyrosine kinase. (1308 aa) |
| | WNT2 | Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa) |
| | MET | MET proto-oncogene, receptor tyrosine kinase. (1387 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) |
| | FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (592 aa) |
| | CAMK2B | Calcium/calmodulin dependent protein kinase II beta. (671 aa) |
| | FZD7 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (571 aa) |
| | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2. (2698 aa) |
| | ESR1 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (589 aa) |
| | HGF | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (729 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa) |
| | NANOG | Homeobox domain-containing protein. (309 aa) |
| | PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa) |
| | ITGB5 | Integrin beta; Belongs to the integrin beta chain family. (800 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (383 aa) |
| | MRAS | Muscle RAS oncogene homolog. (208 aa) |
| | FGF2 | Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. (156 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (445 aa) |
| | F7FNN8_MONDO | Uncharacterized protein. (199 aa) |
| | VTN | SMB domain-containing protein. (466 aa) |
| | HPSE | Heparanase. (544 aa) |
| | ITGA2 | Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa) |
| | TLR4 | Toll like receptor 4; Belongs to the Toll-like receptor family. (838 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (731 aa) |
| | LOC100020922 | Uncharacterized protein; Belongs to the peptidase C1 family. (344 aa) |
| | PPP1R12A | Protein phosphatase 1 regulatory subunit. (878 aa) |
| | KDR | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1349 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | TWIST2 | Twist family bHLH transcription factor 2. (160 aa) |
| | LOC100016601 | Uncharacterized protein. (374 aa) |
| | CDC42 | Cell division cycle 42. (191 aa) |
| | VAV1 | Vav guanine nucleotide exchange factor 1. (846 aa) |
| | F7CI75_MONDO | Uncharacterized protein. (223 aa) |
| | BRAF | B-Raf proto-oncogene, serine/threonine kinase. (563 aa) |
| | TFAP4 | Transcription factor AP-4. (347 aa) |
| | WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (419 aa) |
| | TLR2 | Toll like receptor 2; Belongs to the Toll-like receptor family. (785 aa) |
| | LOC100020439 | Uncharacterized protein; Belongs to the actin family. (374 aa) |
| | HCLS1 | SH3 domain-containing protein. (408 aa) |
| | KRAS-2 | GTPase KRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304- dependent manner (By similarity); Belongs to the small GTPase superfamily. Ras family. (194 aa) |
| | MSN | Moesin. (574 aa) |
| | ITGB1 | Integrin beta; Belongs to the integrin beta chain family. (802 aa) |
| | IQGAP1 | IQ motif containing GTPase activating protein 1. (1657 aa) |
| | HPSE2-2 | Uncharacterized protein. (196 aa) |
| | WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (427 aa) |
| | LOC100012857 | Uncharacterized protein; Belongs to the peptidase C1 family. (335 aa) |
| | NUDT16L1 | Nudix hydrolase 16 like 1. (210 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa) |
| | THBS1 | Thrombospondin 1. (1197 aa) |
| | TIMP3 | NTR domain-containing protein. (211 aa) |
| | FLNA | Filamin A. (2558 aa) |
| | LOC100013113 | Uncharacterized protein; Belongs to the peptidase C1 family. (333 aa) |
| | CAV2 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa) |
| | ACTG1 | Uncharacterized protein. (375 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (641 aa) |
| | PPP1CC | Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (318 aa) |
| | LOC654275 | Caspase-3-like protein 2; Belongs to the peptidase C14A family. (276 aa) |
| | FN1 | Fibronectin 1. (2482 aa) |
| | RRAS | RAS related. (255 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | EZR | Ezrin. (587 aa) |
| | NRAS | GTPase NRas. (195 aa) |
| | PRKACA | Protein kinase cAMP-activated catalytic subunit alpha; Belongs to the protein kinase superfamily. (343 aa) |
| | DROSHA | Drosha ribonuclease III. (1402 aa) |
| | RRAS2 | Uncharacterized protein. (200 aa) |
| | ERBB3 | Erb-b2 receptor tyrosine kinase 3. (1343 aa) |
| | ARAF | Uncharacterized protein. (198 aa) |
| | CCND1 | Uncharacterized protein. (67 aa) |
| | TIAM1 | T cell lymphoma invasion and metastasis 1. (1575 aa) |
| | CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (242 aa) |
| | ERBB2 | Receptor protein-tyrosine kinase. (1257 aa) |
| | SDC4 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (197 aa) |
| | LOC100012978 | Uncharacterized protein; Belongs to the peptidase C1 family. (346 aa) |
| | ANK2 | Uncharacterized protein. (1806 aa) |
| | STAT3 | Signal transducer and activator of transcription. (805 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (335 aa) |
| | PTK2 | Uncharacterized protein. (161 aa) |
| | WNT9A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa) |
| | ANK1 | Ankyrin 1. (1430 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1074 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (364 aa) |
| | WNT5B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (447 aa) |
| | FRS2 | IRS-type PTB domain-containing protein. (508 aa) |
| | ITPR3 | Inositol 1,4,5-trisphosphate receptor type 3. (2608 aa) |
| | VAV3 | Vav guanine nucleotide exchange factor 3. (875 aa) |
| | ROCK1 | Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1322 aa) |
| | SIRT6 | Uncharacterized protein. (547 aa) |
| | PLAUR | Uncharacterized protein. (308 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (328 aa) |
| | ANK3 | Uncharacterized protein. (1089 aa) |
| | WNT8B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (328 aa) |
| | RHOA | Uncharacterized protein. (193 aa) |
| | GAB1 | GRB2 associated binding protein 1. (743 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR. (1040 aa) |
| | CAMK2D | Protein kinase domain-containing protein. (145 aa) |
| | IGF1R | Tyrosine-protein kinase receptor. (1259 aa) |
| | SDC1 | Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (65 aa) |
| | FZD10 | Frizzled class receptor 10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa) |
| | HRAS | GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (189 aa) |
| | ROCK2 | Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1482 aa) |
