STRINGSTRING
GADD45A GADD45A RET RET GADD45G GADD45G RXRG RXRG MYC MYC TFG TFG NCOA4 NCOA4 CDH1 CDH1 PPARG PPARG MAP2K1 MAP2K1 CTNNB1 CTNNB1 TPR TPR CDKN1A CDKN1A BAK1 BAK1 RXRB RXRB TCF7L1 TCF7L1 MAPK3 MAPK3 MAPK1 MAPK1 F7FNN8_MONDO F7FNN8_MONDO DDB2 DDB2 LEF1 LEF1 TCF7 TCF7 BRAF BRAF POLK POLK KRAS-2 KRAS-2 TPM3 TPM3 NRAS NRAS BAX BAX CCND1 CCND1 TCF7L2 TCF7L2 ENSMODP00000053344 ENSMODP00000053344 PAX8 PAX8 SIRT6 SIRT6 HRAS HRAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GADD45AGrowth arrest and DNA damage inducible alpha. (168 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1105 aa)
GADD45GGrowth arrest and DNA damage inducible gamma. (159 aa)
RXRGRetinoid X receptor gamma. (467 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (435 aa)
TFGTrafficking from ER to golgi regulator. (404 aa)
NCOA4Nuclear receptor coactivator 4. (621 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (888 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (486 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
CTNNB1Catenin beta 1. (781 aa)
TPRTranslocated promoter region, nuclear basket protein. (2364 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (164 aa)
BAK1BCL2 antagonist/killer 1. (204 aa)
RXRBRetinoid X receptor beta. (530 aa)
TCF7L1Transcription factor 7 like 1. (613 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa)
F7FNN8_MONDOUncharacterized protein. (199 aa)
DDB2WD_REPEATS_REGION domain-containing protein. (480 aa)
LEF1Lymphoid enhancer binding factor 1. (401 aa)
TCF7Transcription factor 7. (442 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (563 aa)
POLKDNA polymerase kappa. (859 aa)
KRAS-2GTPase KRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304- dependent manner (By similarity); Belongs to the small GTPase superfamily. Ras family. (194 aa)
TPM3Tropomyosin 3; Belongs to the tropomyosin family. (285 aa)
NRASGTPase NRas. (195 aa)
BAXUncharacterized protein. (296 aa)
CCND1Uncharacterized protein. (67 aa)
TCF7L2Transcription factor 7 like 2. (579 aa)
ENSMODP00000053344WD_REPEATS_REGION domain-containing protein. (474 aa)
PAX8Paired box 8. (458 aa)
SIRT6Uncharacterized protein. (547 aa)
HRASGTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (189 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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