(5 nodes) Cul4-RING E3 ubiquitin ligase complex, and Cul3-RING ubiquitin ligase complex network (Penicillium roqueforti)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rbx1	RING-box protein 1. (117 aa)
	W6Q438_PENRF	Cullin, N-terminal; Belongs to the cullin family. (873 aa)
	W6Q483_PENRF	Cleavage/polyadenylation specificity factor, A subunit, C-terminal. (1143 aa)
	W6QAH4_PENRF	WD40/YVTN repeat-like-containing domain. (707 aa)
	W6QH92_PENRF	WD40/YVTN repeat-like-containing domain. (491 aa)

Your Current Organism:

Penicillium roqueforti

NCBI taxonomy Id: 1365484
Other names: P. roqueforti FM164, Penicillium roqueforti FM164

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
W6Q438_PENRF	W6Q483_PENRF	W6Q438	W6Q483	Cullin, N-terminal; Belongs to the cullin family.	Cleavage/polyadenylation specificity factor, A subunit, C-terminal.	0.999
W6Q438_PENRF	W6QAH4_PENRF	W6Q438	W6QAH4	Cullin, N-terminal; Belongs to the cullin family.	WD40/YVTN repeat-like-containing domain.	0.995
W6Q438_PENRF	W6QH92_PENRF	W6Q438	W6QH92	Cullin, N-terminal; Belongs to the cullin family.	WD40/YVTN repeat-like-containing domain.	0.980
W6Q438_PENRF	rbx1	W6Q438	W6PV48	Cullin, N-terminal; Belongs to the cullin family.	RING-box protein 1.	0.988
W6Q483_PENRF	W6Q438_PENRF	W6Q483	W6Q438	Cleavage/polyadenylation specificity factor, A subunit, C-terminal.	Cullin, N-terminal; Belongs to the cullin family.	0.999
W6Q483_PENRF	W6QAH4_PENRF	W6Q483	W6QAH4	Cleavage/polyadenylation specificity factor, A subunit, C-terminal.	WD40/YVTN repeat-like-containing domain.	0.999
W6Q483_PENRF	W6QH92_PENRF	W6Q483	W6QH92	Cleavage/polyadenylation specificity factor, A subunit, C-terminal.	WD40/YVTN repeat-like-containing domain.	0.999
W6Q483_PENRF	rbx1	W6Q483	W6PV48	Cleavage/polyadenylation specificity factor, A subunit, C-terminal.	RING-box protein 1.	0.999
W6QAH4_PENRF	W6Q438_PENRF	W6QAH4	W6Q438	WD40/YVTN repeat-like-containing domain.	Cullin, N-terminal; Belongs to the cullin family.	0.995
W6QAH4_PENRF	W6Q483_PENRF	W6QAH4	W6Q483	WD40/YVTN repeat-like-containing domain.	Cleavage/polyadenylation specificity factor, A subunit, C-terminal.	0.999
W6QAH4_PENRF	W6QH92_PENRF	W6QAH4	W6QH92	WD40/YVTN repeat-like-containing domain.	WD40/YVTN repeat-like-containing domain.	0.797
W6QAH4_PENRF	rbx1	W6QAH4	W6PV48	WD40/YVTN repeat-like-containing domain.	RING-box protein 1.	0.992
W6QH92_PENRF	W6Q438_PENRF	W6QH92	W6Q438	WD40/YVTN repeat-like-containing domain.	Cullin, N-terminal; Belongs to the cullin family.	0.980
W6QH92_PENRF	W6Q483_PENRF	W6QH92	W6Q483	WD40/YVTN repeat-like-containing domain.	Cleavage/polyadenylation specificity factor, A subunit, C-terminal.	0.999
W6QH92_PENRF	W6QAH4_PENRF	W6QH92	W6QAH4	WD40/YVTN repeat-like-containing domain.	WD40/YVTN repeat-like-containing domain.	0.797
W6QH92_PENRF	rbx1	W6QH92	W6PV48	WD40/YVTN repeat-like-containing domain.	RING-box protein 1.	0.973
rbx1	W6Q438_PENRF	W6PV48	W6Q438	RING-box protein 1.	Cullin, N-terminal; Belongs to the cullin family.	0.988
rbx1	W6Q483_PENRF	W6PV48	W6Q483	RING-box protein 1.	Cleavage/polyadenylation specificity factor, A subunit, C-terminal.	0.999
rbx1	W6QAH4_PENRF	W6PV48	W6QAH4	RING-box protein 1.	WD40/YVTN repeat-like-containing domain.	0.992
rbx1	W6QH92_PENRF	W6PV48	W6QH92	RING-box protein 1.	WD40/YVTN repeat-like-containing domain.	0.973