23 items (Penicillium roqueforti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	dbp5	ATP-dependent RNA helicase dbp5; Belongs to the DEAD box helicase family. (485 aa)
	pkcA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1068 aa)
	nip1	Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (860 aa)
	PRT1	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. (743 aa)
	W6QHN7_PENRF	Mannosyltransferase 1, CMT1. (404 aa)
	W6QHQ1_PENRF	Mannosyltransferase 1, CMT1. (521 aa)
	W6QHT2_PENRF	Dcp1-like decapping. (327 aa)
	W6QIU7_PENRF	RNA recognition motif domain, eukaryote. (482 aa)
	W6QMJ2_PENRF	RNA recognition motif 2. (710 aa)
	dhh1	ATP-dependent RNA helicase dhh1; Belongs to the DEAD box helicase family. (517 aa)
	W6QD25_PENRF	Unnamed protein product [Penicillium chrysogenum]. (251 aa)
	W6Q1P2_PENRF	Winged helix-turn-helix transcription repressor DNA-binding. (951 aa)
	GIS2	Zinc finger protein GIS2. (247 aa)
	W6PYE8_PENRF	Topoisomerase II-associated protein PAT1. (818 aa)
	W6PWM3_PENRF	Fibronectin-binding A, N-terminal. (1091 aa)
	W6PW85_PENRF	Like-Sm (LSM) domain. (560 aa)
	SU2	Eukaryotic peptide chain release factor subunit 1. (531 aa)
	W6Q2H4_PENRF	LsmAD domain. (1046 aa)
	W6Q4W2_PENRF	NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (697 aa)
	exo2	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. (1392 aa)
	W6R136_PENRF	WD40/YVTN repeat-like-containing domain. (1500 aa)
	tif451	Eukaryotic translation initiation factor 4E-1; Belongs to the eukaryotic initiation factor 4E family. (238 aa)
	W6PVJ9_PENRF	Armadillo-type fold. (1429 aa)

Your Current Organism:

Penicillium roqueforti

NCBI taxonomy Id: 1365484
Other names: P. roqueforti FM164, Penicillium roqueforti FM164

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GIS2	W6Q1P2_PENRF	W6PYQ5	W6Q1P2	Zinc finger protein GIS2.	Winged helix-turn-helix transcription repressor DNA-binding.	0.511
GIS2	exo2	W6PYQ5	W6Q5U5	Zinc finger protein GIS2.	5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.	0.538
PRT1	SU2	W6PTB4	W6PW17	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.	Eukaryotic peptide chain release factor subunit 1.	0.755
PRT1	W6PVJ9_PENRF	W6PTB4	W6PVJ9	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.	Armadillo-type fold.	0.770
PRT1	W6QHN7_PENRF	W6PTB4	W6QHN7	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.	Mannosyltransferase 1, CMT1.	0.770
PRT1	W6QHQ1_PENRF	W6PTB4	W6QHQ1	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.	Mannosyltransferase 1, CMT1.	0.770
PRT1	W6QIU7_PENRF	W6PTB4	W6QIU7	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.	RNA recognition motif domain, eukaryote.	0.463
PRT1	dhh1	W6PTB4	W6Q6S6	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.	ATP-dependent RNA helicase dhh1; Belongs to the DEAD box helicase family.	0.630
PRT1	nip1	W6PTB4	W6PSY8	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.	Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.999
PRT1	tif451	W6PTB4	W6QVJ3	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.	Eukaryotic translation initiation factor 4E-1; Belongs to the eukaryotic initiation factor 4E family.	0.874
SU2	PRT1	W6PW17	W6PTB4	Eukaryotic peptide chain release factor subunit 1.	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.	0.755
SU2	W6PVJ9_PENRF	W6PW17	W6PVJ9	Eukaryotic peptide chain release factor subunit 1.	Armadillo-type fold.	0.425
SU2	W6QHN7_PENRF	W6PW17	W6QHN7	Eukaryotic peptide chain release factor subunit 1.	Mannosyltransferase 1, CMT1.	0.425
SU2	W6QHQ1_PENRF	W6PW17	W6QHQ1	Eukaryotic peptide chain release factor subunit 1.	Mannosyltransferase 1, CMT1.	0.425
SU2	W6QHT2_PENRF	W6PW17	W6QHT2	Eukaryotic peptide chain release factor subunit 1.	Dcp1-like decapping.	0.584
SU2	dbp5	W6PW17	W6Q640	Eukaryotic peptide chain release factor subunit 1.	ATP-dependent RNA helicase dbp5; Belongs to the DEAD box helicase family.	0.443
SU2	nip1	W6PW17	W6PSY8	Eukaryotic peptide chain release factor subunit 1.	Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.604
SU2	tif451	W6PW17	W6QVJ3	Eukaryotic peptide chain release factor subunit 1.	Eukaryotic translation initiation factor 4E-1; Belongs to the eukaryotic initiation factor 4E family.	0.581
W6PVJ9_PENRF	PRT1	W6PVJ9	W6PTB4	Armadillo-type fold.	Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family.	0.770
W6PVJ9_PENRF	SU2	W6PVJ9	W6PW17	Armadillo-type fold.	Eukaryotic peptide chain release factor subunit 1.	0.425