59 items (Penicillium roqueforti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	W6QGV1_PENRF	NAD-dependent deacetylase, sirtuin family. (379 aa)
	LYS12	Homoisocitrate dehydrogenase, mitochondrial. (350 aa)
	W6QJ51_PENRF	NAD(P)-binding domain. (166 aa)
	W6QJF5_PENRF	Mss4-like. (140 aa)
	NUO51	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (495 aa)
	W6QKS6_PENRF	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (338 aa)
	W6QK36_PENRF	NAD-dependent protein deacetylase; Belongs to the sirtuin family. Class I subfamily. (364 aa)
	W6R7I4_PENRF	Haloacid dehalogenase/epoxide hydrolase. (236 aa)
	W6R5H6_PENRF	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (343 aa)
	W6R4V7_PENRF	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (338 aa)
	W6R234_PENRF	Oxoglutarate/iron-dependent dioxygenase. (686 aa)
	W6R0H8_PENRF	NAD-dependent deacetylase, sirtuin family. (317 aa)
	his-3	Histidine biosynthesis trifunctional protein. (871 aa)
	leu2A	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (364 aa)
	W6QUK7_PENRF	Mss4-like. (136 aa)
	aciA	Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (363 aa)
	W6QTN9_PENRF	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (348 aa)
	W6QRZ9_PENRF	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (341 aa)
	sir2	NAD-dependent histone deacetylase sir2. (486 aa)
	W6QQF1_PENRF	Mss4-like. (188 aa)
	ldhA	D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (347 aa)
	Hibadh	3-hydroxyisobutyrate dehydrogenase, mitochondrial. (360 aa)
	leu2B	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (366 aa)
	W6QMX8_PENRF	NAD-dependent deacetylase, sirtuin family. (72 aa)
	W6QLY2_PENRF	DUF1752 domain-containing protein. (584 aa)
	W6QLF8_PENRF	NAD-dependent deacetylase, sirtuin family. (565 aa)
	W6PSS2_PENRF	Genomic scaffold, ProqFM164S01. (77 aa)
	W6PTH7_PENRF	Isocitrate/isopropylmalate dehydrogenase. (365 aa)
	W6PVQ4_PENRF	NAD(P)-binding domain. (339 aa)
	W6PX88_PENRF	Fatty oxidation complex, alpha subunit FadB. (338 aa)
	idh2	Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (384 aa)
	mmgB	Probable 3-hydroxybutyryl-CoA dehydrogenase. (319 aa)
	W6PY09_PENRF	Fatty oxidation complex, alpha subunit FadB. (165 aa)
	arg-6	Protein arg-6, mitochondrial; In the N-terminal section; belongs to the acetylglutamate kinase family. (895 aa)
	W6PZR3_PENRF	Glycerol-3-phosphate dehydrogenase [NAD(+)]. (441 aa)
	W6Q0A9_PENRF	Prephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family. (434 aa)
	W6Q0T9_PENRF	NmrA-like. (215 aa)
	W6Q1J5_PENRF	D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (462 aa)
	MAE1	Malic enzyme. (574 aa)
	W6Q4J6_PENRF	Six-bladed beta-propeller, TolB-like. (611 aa)
	W6Q4N2_PENRF	Fatty oxidation complex, alpha subunit FadB. (316 aa)
	W6Q4Z0_PENRF	D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (339 aa)
	W6Q5X7_PENRF	Fatty oxidation complex, alpha subunit FadB. (282 aa)
	W6Q6A5_PENRF	Glyceraldehyde-3-phosphate dehydrogenase. (293 aa)
	W6Q6D5_PENRF	Probable aspartate-semialdehyde dehydrogenase. (364 aa)
	icdA	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (412 aa)
	W6Q8R1_PENRF	Transcription factor, fungi. (668 aa)
	W6Q9J5_PENRF	Genomic scaffold, ProqFM164S03. (70 aa)
	W6Q9N0_PENRF	Isocitrate/isopropylmalate dehydrogenase. (357 aa)
	W6QA93_PENRF	Genomic scaffold, ProqFM164S03. (209 aa)
	W6QAM7_PENRF	NAD(P)-binding domain. (358 aa)
	dgoD	D-galactonate dehydratase. (383 aa)
	W6QDJ4_PENRF	2-hydroxyacid dehydrogenase homolog 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (331 aa)
	W6QDV5_PENRF	Genomic scaffold, ProqFM164S02. (330 aa)
	nuo-49	NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrial; Belongs to the complex I 49 kDa subunit family. (473 aa)
	IDH1	Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (384 aa)
	W6QEN4_PENRF	Mss4-like. (149 aa)
	W6QFI4_PENRF	Zn(2)-C6 fungal-type DNA-binding domain. (653 aa)
	W6QGK1_PENRF	HAD-like domain. (151 aa)

Your Current Organism:

Penicillium roqueforti

NCBI taxonomy Id: 1365484
Other names: P. roqueforti FM164, Penicillium roqueforti FM164

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Hibadh	W6PX88_PENRF	W6QPC1	W6PX88	3-hydroxyisobutyrate dehydrogenase, mitochondrial.	Fatty oxidation complex, alpha subunit FadB.	0.668
Hibadh	W6PY09_PENRF	W6QPC1	W6PY09	3-hydroxyisobutyrate dehydrogenase, mitochondrial.	Fatty oxidation complex, alpha subunit FadB.	0.639
Hibadh	W6Q4J6_PENRF	W6QPC1	W6Q4J6	3-hydroxyisobutyrate dehydrogenase, mitochondrial.	Six-bladed beta-propeller, TolB-like.	0.639
Hibadh	W6Q4N2_PENRF	W6QPC1	W6Q4N2	3-hydroxyisobutyrate dehydrogenase, mitochondrial.	Fatty oxidation complex, alpha subunit FadB.	0.897
Hibadh	W6Q5X7_PENRF	W6QPC1	W6Q5X7	3-hydroxyisobutyrate dehydrogenase, mitochondrial.	Fatty oxidation complex, alpha subunit FadB.	0.639
Hibadh	W6Q6A5_PENRF	W6QPC1	W6Q6A5	3-hydroxyisobutyrate dehydrogenase, mitochondrial.	Glyceraldehyde-3-phosphate dehydrogenase.	0.493
Hibadh	mmgB	W6QPC1	W6PXY0	3-hydroxyisobutyrate dehydrogenase, mitochondrial.	Probable 3-hydroxybutyryl-CoA dehydrogenase.	0.639
IDH1	LYS12	W6QER6	W6QGX3	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	Homoisocitrate dehydrogenase, mitochondrial.	0.942
IDH1	MAE1	W6QER6	W6Q440	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	Malic enzyme.	0.479
IDH1	NUO51	W6QER6	W6QKU8	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain.	0.723
IDH1	W6PTH7_PENRF	W6QER6	W6PTH7	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	Isocitrate/isopropylmalate dehydrogenase.	0.941
IDH1	W6Q6D5_PENRF	W6QER6	W6Q6D5	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	Probable aspartate-semialdehyde dehydrogenase.	0.411
IDH1	W6Q8R1_PENRF	W6QER6	W6Q8R1	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	Transcription factor, fungi.	0.935
IDH1	W6Q9J5_PENRF	W6QER6	W6Q9J5	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	Genomic scaffold, ProqFM164S03.	0.814
IDH1	W6Q9N0_PENRF	W6QER6	W6Q9N0	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	Isocitrate/isopropylmalate dehydrogenase.	0.941
IDH1	W6QDV5_PENRF	W6QER6	W6QDV5	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	Genomic scaffold, ProqFM164S02.	0.914
IDH1	W6QEN4_PENRF	W6QER6	W6QEN4	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	Mss4-like.	0.935
IDH1	W6QGK1_PENRF	W6QER6	W6QGK1	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	HAD-like domain.	0.814
IDH1	W6QJF5_PENRF	W6QER6	W6QJF5	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	Mss4-like.	0.935
IDH1	W6QQF1_PENRF	W6QER6	W6QQF1	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	Mss4-like.	0.935