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pyc pyc W6PRU6_PENRF W6PRU6_PENRF W6PSC9_PENRF W6PSC9_PENRF W6PSM6_PENRF W6PSM6_PENRF W6PSQ0_PENRF W6PSQ0_PENRF W6PSX4_PENRF W6PSX4_PENRF W6PSZ6_PENRF W6PSZ6_PENRF thi4 thi4 W6PUF3_PENRF W6PUF3_PENRF W6PUR9_PENRF W6PUR9_PENRF W6PVG2_PENRF W6PVG2_PENRF W6PVH5_PENRF W6PVH5_PENRF W6PW83_PENRF W6PW83_PENRF OYE2 OYE2 trpC trpC W6PYG6_PENRF W6PYG6_PENRF W6PYN8_PENRF W6PYN8_PENRF W6PZ57_PENRF W6PZ57_PENRF W6PZA3_PENRF W6PZA3_PENRF W6PZB5_PENRF W6PZB5_PENRF hisHF hisHF ARO4 ARO4 W6Q0F7_PENRF W6Q0F7_PENRF W6Q0L5_PENRF W6Q0L5_PENRF Hao1 Hao1 qutR qutR ifgGI ifgGI W6Q2K6_PENRF W6Q2K6_PENRF tpiA tpiA MOCS1 MOCS1 W6Q5I2_PENRF W6Q5I2_PENRF W6Q5W7_PENRF W6Q5W7_PENRF agl1 agl1 LEU4 LEU4 W6Q6F1_PENRF W6Q6F1_PENRF BNA6 BNA6 W6Q6Y5_PENRF W6Q6Y5_PENRF W6Q750_PENRF W6Q750_PENRF W6Q7E8_PENRF W6Q7E8_PENRF W6Q8J7_PENRF W6Q8J7_PENRF fgaOx3 fgaOx3 aro-8 aro-8 gua1 gua1 W6QAU4_PENRF W6QAU4_PENRF DUS1 DUS1 CYB2 CYB2 W6QCL4_PENRF W6QCL4_PENRF W6QCR7_PENRF W6QCR7_PENRF dapA-2 dapA-2 W6QE74_PENRF W6QE74_PENRF W6QEG7_PENRF W6QEG7_PENRF W6QFH5_PENRF W6QFH5_PENRF W6QFZ5_PENRF W6QFZ5_PENRF FAS1 FAS1 trp-3 trp-3 RPE1 RPE1 W6QGJ2_PENRF W6QGJ2_PENRF pyroA pyroA W6QGX6_PENRF W6QGX6_PENRF his-6 his-6 lys1 lys1 W6QHH4_PENRF W6QHH4_PENRF W6QHS4_PENRF W6QHS4_PENRF fbaA fbaA OPR12 OPR12 W6QIC7_PENRF W6QIC7_PENRF W6QIP6_PENRF W6QIP6_PENRF mpaF mpaF tal1 tal1 W6QJ07_PENRF W6QJ07_PENRF W6QK82_PENRF W6QK82_PENRF W6QLD5_PENRF W6QLD5_PENRF W6QLJ8_PENRF W6QLJ8_PENRF HMGCL HMGCL W6QML5_PENRF W6QML5_PENRF W6QMU4_PENRF W6QMU4_PENRF BIO2 BIO2 W6QPP6_PENRF W6QPP6_PENRF W6QSL1_PENRF W6QSL1_PENRF dus3 dus3 aroM aroM W6R0I7_PENRF W6R0I7_PENRF W6R157_PENRF W6R157_PENRF W6R211_PENRF W6R211_PENRF deoC deoC W6R9H3_PENRF W6R9H3_PENRF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pycPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1164 aa)
W6PRU6_PENRFDihydrodipicolinate synthetase-like; Belongs to the DapA family. (312 aa)
W6PSC9_PENRFGlycoside hydrolase, family 56, sperm surface protein PH20. (945 aa)
W6PSM6_PENRFAldolase-type TIM barrel. (369 aa)
W6PSQ0_PENRFAldolase-type TIM barrel. (348 aa)
W6PSX4_PENRFTIM-barrel signal transduction protein, predicted. (279 aa)
W6PSZ6_PENRFAldolase-type TIM barrel. (421 aa)
thi4Probable thiamine biosynthetic bifunctional enzyme. (517 aa)
W6PUF3_PENRFTriosephosphate isomerase. (284 aa)
W6PUR9_PENRFDihydroorotate dehydrogenase, class 1/ 2. (518 aa)
W6PVG2_PENRFAlpha-hydroxy acid dehydrogenase, FMN-dependent. (427 aa)
W6PVH5_PENRFAldolase-type TIM barrel. (355 aa)
W6PW83_PENRFGlycoside hydrolase, family 56, sperm surface protein PH20. (655 aa)
OYE2NADPH dehydrogenase 2. (367 aa)
trpCMultifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. (752 aa)
W6PYG6_PENRFOrotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. (259 aa)
W6PYN8_PENRFAldolase-type TIM barrel. (272 aa)
W6PZ57_PENRFFructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (288 aa)
W6PZA3_PENRFAlpha-hydroxy acid dehydrogenase, FMN-dependent. (402 aa)
W6PZB5_PENRFFatty acid synthase, beta subunit, fungi. (1259 aa)
hisHFImidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (551 aa)
ARO4Phospho-2-dehydro-3-deoxyheptonate aldolase. (372 aa)
W6Q0F7_PENRFDelta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (377 aa)
W6Q0L5_PENRFAldolase-type TIM barrel. (123 aa)
Hao1Hydroxyacid oxidase 1. (366 aa)
qutRQuinate repressor protein. (899 aa)
ifgGIChanoclavine-I aldehyde reductase ifgG; Chanoclavine-I aldehyde reductase; part of the gene cluster that mediates the biosynthesis of isofumigaclavines, fungal ergot alkaloids. The tryptophan dimethylallyltransferase ifgA catalyzes the first step of ergot alkaloid biosynthesis by condensing dimethylallyl diphosphate (DMAP) and tryptophan to form 4- dimethylallyl-L-tryptophan. The second step is catalyzed by the methyltransferase ifgB that methylates 4- dimethylallyl-L-tryptophan in the presence of S-adenosyl-L-methionine, resulting in the formation of N-methyl-dimethylallyl-L-tryptopha [...] (375 aa)
W6Q2K6_PENRFAldolase-type TIM barrel. (422 aa)
tpiATriosephosphate isomerase. (249 aa)
MOCS1Molybdenum cofactor biosynthesis protein 1. (653 aa)
W6Q5I2_PENRFAlpha-hydroxy acid dehydrogenase, FMN-dependent. (386 aa)
W6Q5W7_PENRFAlpha-galactosidase; Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides. Belongs to the glycosyl hydrolase. (746 aa)
agl1Alpha-galactosidase. (436 aa)
LEU42-isopropylmalate synthase. (638 aa)
W6Q6F1_PENRFPutative NADPH dehydrogenase C23G7.10c. (443 aa)
BNA6Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (313 aa)
W6Q6Y5_PENRFGenomic scaffold, ProqFM164S02. (85 aa)
W6Q750_PENRFTM1410 hypothetical-related protein. (323 aa)
W6Q7E8_PENRFDeoxyribose-phosphate aldolase. (265 aa)
W6Q8J7_PENRFtRNA-dihydrouridine synthase. (508 aa)
fgaOx3Chanoclavine-I aldehyde reductase fgaOx3; Chanoclavine-I aldehyde reductase; part of the gene cluster that mediates the biosynthesis of isofumigaclavines, fungal ergot alkaloids. The tryptophan dimethylallyltransferase ifgA catalyzes the first step of ergot alkaloid biosynthesis by condensing dimethylallyl diphosphate (DMAP) and tryptophan to form 4- dimethylallyl-L-tryptophan. The second step is catalyzed by the methyltransferase ifgB that methylates 4- dimethylallyl-L-tryptophan in the presence of S-adenosyl-L-methionine, resulting in the formation of N-methyl-dimethylallyl-L-tryptop [...] (369 aa)
aro-8Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family. (459 aa)
gua1Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (546 aa)
W6QAU4_PENRFAldolase-type TIM barrel. (350 aa)
DUS1tRNA-dihydrouridine synthase 1. (534 aa)
CYB2Cytochrome b2, mitochondrial; Belongs to the cytochrome b5 family. (499 aa)
W6QCL4_PENRFLipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (416 aa)
W6QCR7_PENRFAlpha-hydroxy acid dehydrogenase, FMN-dependent. (369 aa)
dapA-2Dihydrodipicolinate synthase; Belongs to the DapA family. (296 aa)
W6QE74_PENRFAlpha-hydroxy acid dehydrogenase, FMN-dependent. (421 aa)
W6QEG7_PENRFAldolase-type TIM barrel. (717 aa)
W6QFH5_PENRFProbable 4-hydroxy-2-oxoglutarate aldolase, mitochondrial; Belongs to the DapA family. (311 aa)
W6QFZ5_PENRFAlpha-hydroxy acid dehydrogenase, FMN-dependent. (415 aa)
FAS1Fatty acid synthase subunit beta; Belongs to the fungal fatty acid synthetase subunit beta family. (2082 aa)
trp-3Tryptophan synthase. (723 aa)
RPE1Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (254 aa)
W6QGJ2_PENRFAldolase-type TIM barrel. (351 aa)
pyroAPyridoxine biosynthesis protein pyroA; Belongs to the PdxS/SNZ family. (305 aa)
W6QGX6_PENRFCrotonase, core. (597 aa)
his-61-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (256 aa)
lys1Homocitrate synthase, mitochondrial; Belongs to the alpha-IPM synthase/homocitrate synthase family. (470 aa)
W6QHH4_PENRFNitronate monooxygenase. (332 aa)
W6QHS4_PENRFCytochrome b5; Belongs to the cytochrome b5 family. (496 aa)
fbaAFructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (360 aa)
OPR12Putative 12-oxophytodienoate reductase 12. (385 aa)
W6QIC7_PENRFDihydrodipicolinate synthetase-like; Belongs to the DapA family. (335 aa)
W6QIP6_PENRFAldolase-type TIM barrel. (408 aa)
mpaFInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity). Part of the gene cluster that mediates the biosynthesis of mycophenolic acid (MPA), the first isolated antibiotic natural product in the world. Involved in self resistance to MPA, since MPA acts as an inhibitor of IMP dehydrogenases. seems also tot play a role in the biosynthesis of [...] (526 aa)
tal1Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (324 aa)
W6QJ07_PENRFAldolase-type TIM barrel. (56 aa)
W6QK82_PENRFShikimate kinase. (836 aa)
W6QLD5_PENRFPutative 4-hydroxy-2-oxoglutarate aldolase, mitochondrial; Belongs to the DapA family. (329 aa)
W6QLJ8_PENRFDihydrodipicolinate synthetase-like; Belongs to the DapA family. (333 aa)
HMGCLHydroxymethylglutaryl-CoA lyase, mitochondrial. (359 aa)
W6QML5_PENRFAlpha-hydroxy acid dehydrogenase, FMN-dependent. (395 aa)
W6QMU4_PENRFPhospho-2-dehydro-3-deoxyheptonate aldolase. (364 aa)
BIO2Biotin synthase, mitochondrial. (389 aa)
W6QPP6_PENRFAldolase-type TIM barrel. (418 aa)
W6QSL1_PENRF(2R)-phospho-3-sulpholactate synthase, ComA. (230 aa)
dus3tRNA-dihydrouridine(47) synthase [NAD(P)(+)]; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs. (728 aa)
aroM3-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the 2nd section; belongs to the EPSP synthase family. In the 4th section; belongs to the type-I 3-dehydroquinase family. In the N-terminal section; belongs to the dehydroquinate synthase family. (1583 aa)
W6R0I7_PENRFTM1410 hypothetical-related protein. (429 aa)
W6R157_PENRFPutative glutamate synthase [NADPH]. (2148 aa)
W6R211_PENRFTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (324 aa)
deoCDeoxyribose-phosphate aldolase. (260 aa)
W6R9H3_PENRFAlpha-hydroxy acid dehydrogenase, FMN-dependent. (423 aa)
Your Current Organism:
Penicillium roqueforti
NCBI taxonomy Id: 1365484
Other names: P. roqueforti FM164, Penicillium roqueforti FM164
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