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nuo-24 nuo-24 pol1 pol1 W6PVX7_PENRF W6PVX7_PENRF SDH2 SDH2 W6PYS7_PENRF W6PYS7_PENRF cfd1 cfd1 GRX5 GRX5 nbp35 nbp35 W6Q9C3_PENRF W6Q9C3_PENRF W6QCI8_PENRF W6QCI8_PENRF W6QCL4_PENRF W6QCL4_PENRF W6QER9_PENRF W6QER9_PENRF dre2 dre2 W6QGQ6_PENRF W6QGQ6_PENRF pol2 pol2 hxA hxA NUO51 NUO51 lysA lysA W6QLG1_PENRF W6QLG1_PENRF BIO2 BIO2 pol3 pol3 ACO1 ACO1 W6R157_PENRF W6R157_PENRF ELP3 ELP3
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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co-expression
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nuo-24NADH-ubiquinone oxidoreductase 24 kDa subunit, mitochondrial. (268 aa)
pol1DNA polymerase. (1461 aa)
W6PVX7_PENRFIron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (201 aa)
SDH2Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (271 aa)
W6PYS7_PENRFDNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (501 aa)
cfd1Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (324 aa)
GRX5Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. (157 aa)
nbp35Cytosolic Fe-S cluster assembly factor nbp35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (342 aa)
W6Q9C3_PENRF[NiFe]-hydrogenase-3-type complex, small subunit/NADH:quinone oxidoreductase, subunit NuoB; Belongs to the complex I 20 kDa subunit family. (210 aa)
W6QCI8_PENRFDNA polymerase. (1695 aa)
W6QCL4_PENRFLipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (416 aa)
W6QER9_PENRFNADH-ubiquinone oxidoreductase 19.3 kDa subunit, mitochondrial; Belongs to the complex I 20 kDa subunit family. (230 aa)
dre2Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] (318 aa)
W6QGQ6_PENRFElectron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (635 aa)
pol2DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2226 aa)
hxAXanthine dehydrogenase. (1357 aa)
NUO51NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (495 aa)
lysAHomoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (786 aa)
W6QLG1_PENRFAconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (798 aa)
BIO2Biotin synthase, mitochondrial. (389 aa)
pol3DNA polymerase. (1105 aa)
ACO1Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (786 aa)
W6R157_PENRFPutative glutamate synthase [NADPH]. (2148 aa)
ELP3Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (575 aa)
Your Current Organism:
Penicillium roqueforti
NCBI taxonomy Id: 1365484
Other names: P. roqueforti FM164, Penicillium roqueforti FM164
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