STRINGSTRING
purU purU W6QUX9_PENRF W6QUX9_PENRF W6QZR4_PENRF W6QZR4_PENRF W6R147_PENRF W6R147_PENRF W6R2G3_PENRF W6R2G3_PENRF W6R2H5_PENRF W6R2H5_PENRF W6R564_PENRF W6R564_PENRF TRXA TRXA W6Q507_PENRF W6Q507_PENRF ADK ADK HAL3A HAL3A W6Q5R5_PENRF W6Q5R5_PENRF W6Q662_PENRF W6Q662_PENRF ADE1 ADE1 W6Q6S5_PENRF W6Q6S5_PENRF W6Q7V2_PENRF W6Q7V2_PENRF rnr-2 rnr-2 URA6 URA6 W6Q9Z1_PENRF W6Q9Z1_PENRF gua1 gua1 W6QAX8_PENRF W6QAX8_PENRF pyrABCN pyrABCN gda1 gda1 W6QCG0_PENRF W6QCG0_PENRF GUD1 GUD1 ADE17 ADE17 rnr-1 rnr-1 W6QEM8_PENRF W6QEM8_PENRF W6QF69_PENRF W6QF69_PENRF W6QFY7_PENRF W6QFY7_PENRF ADK1 ADK1 YSA1 YSA1 W6QHC8_PENRF W6QHC8_PENRF W6QHG0_PENRF W6QHG0_PENRF W6QHZ7_PENRF W6QHZ7_PENRF UCKL1 UCKL1 mpaF mpaF TXN TXN ndk1 ndk1 W6QJA7_PENRF W6QJA7_PENRF W6QJE3_PENRF W6QJE3_PENRF W6QJJ2_PENRF W6QJJ2_PENRF ura-7 ura-7 ADE1-2 ADE1-2 W6QLB3_PENRF W6QLB3_PENRF W6QLE7_PENRF W6QLE7_PENRF ADE2 ADE2 bsd bsd ADE4 ADE4 W6QM41_PENRF W6QM41_PENRF W6QM44_PENRF W6QM44_PENRF ADE13 ADE13 NUDT1 NUDT1 W6QN07_PENRF W6QN07_PENRF W6QNK8_PENRF W6QNK8_PENRF gua1-2 gua1-2 W6QNQ0_PENRF W6QNQ0_PENRF Pnp Pnp W6QP65_PENRF W6QP65_PENRF W6QP82_PENRF W6QP82_PENRF glr-1 glr-1 W6QPP6_PENRF W6QPP6_PENRF W6QTA0_PENRF W6QTA0_PENRF W6PR92_PENRF W6PR92_PENRF aah1 aah1 ADK2 ADK2 DUT1 DUT1 CDC21 CDC21 W6PU99_PENRF W6PU99_PENRF W6PUR9_PENRF W6PUR9_PENRF W6PV04_PENRF W6PV04_PENRF W6PVT4_PENRF W6PVT4_PENRF fap7 fap7 W6PWJ5_PENRF W6PWJ5_PENRF W6PYG6_PENRF W6PYG6_PENRF W6PYW7_PENRF W6PYW7_PENRF ADE6 ADE6 W6PZE0_PENRF W6PZE0_PENRF DTYMK DTYMK APT1 APT1 ade5 ade5 W6Q0C3_PENRF W6Q0C3_PENRF GUK1 GUK1 ada1 ada1 W6Q1J0_PENRF W6Q1J0_PENRF W6Q1K1_PENRF W6Q1K1_PENRF CDA CDA W6Q222_PENRF W6Q222_PENRF W6Q239_PENRF W6Q239_PENRF HOR2 HOR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
purUFormyltetrahydrofolate deformylase. (287 aa)
W6QUX9_PENRFGlutaredoxin. (101 aa)
W6QZR4_PENRFGenomic scaffold, ProqFM164S03. (368 aa)
W6R147_PENRFHistone-fold. (78 aa)
W6R2G3_PENRFArmadillo-type fold. (1027 aa)
W6R2H5_PENRFNudix hydrolase domain-containing protein. (310 aa)
W6R564_PENRFUncharacterized protein. (119 aa)
TRXAThioredoxin; Belongs to the thioredoxin family. (106 aa)
W6Q507_PENRFNucleoside phosphatase GDA1/CD39; Belongs to the GDA1/CD39 NTPase family. (713 aa)
ADKAdenosine kinase. (349 aa)
HAL3APhosphopantothenoylcysteine decarboxylase. (256 aa)
W6Q5R5_PENRFThioredoxin. (109 aa)
W6Q662_PENRFUncharacterized protein. (414 aa)
ADE1Phosphoribosylaminoimidazole-succinocarboxamide synthase. (301 aa)
W6Q6S5_PENRFPhosphoribosyltransferase. (245 aa)
W6Q7V2_PENRFSrc homology-3 domain. (1107 aa)
rnr-2Ribonucleoside-diphosphate reductase small chain. (384 aa)
URA6Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (209 aa)
W6Q9Z1_PENRFAcyltransferase 3. (541 aa)
gua1Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (546 aa)
W6QAX8_PENRFCTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (588 aa)
pyrABCNProtein pyrABCN. (2244 aa)
gda1Probable guanosine-diphosphatase; Belongs to the GDA1/CD39 NTPase family. (561 aa)
W6QCG0_PENRFGuanylate kinase/L-type calcium channel. (193 aa)
GUD1Probable guanine deaminase. (529 aa)
ADE17Bifunctional purine biosynthesis protein ADE17. (595 aa)
rnr-1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (861 aa)
W6QEM8_PENRF5'-Nucleotidase/apyrase. (543 aa)
W6QF69_PENRFHAD-superfamily hydrolase, subfamily IA, variant 3. (281 aa)
W6QFY7_PENRFL-Aspartase-like. (101 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (257 aa)
YSA1ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family. (226 aa)
W6QHC8_PENRFZn(2)-C6 fungal-type DNA-binding domain. (624 aa)
W6QHG0_PENRFZn(2)-C6 fungal-type DNA-binding domain. (692 aa)
W6QHZ7_PENRFHAD-superfamily hydrolase, subfamily IA, variant 3. (253 aa)
UCKL1Uridine kinase; Belongs to the uridine kinase family. (452 aa)
mpaFInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity). Part of the gene cluster that mediates the biosynthesis of mycophenolic acid (MPA), the first isolated antibiotic natural product in the world. Involved in self resistance to MPA, since MPA acts as an inhibitor of IMP dehydrogenases. seems also tot play a role in the biosynthesis of [...] (526 aa)
TXNThioredoxin; Belongs to the thioredoxin family. (137 aa)
ndk1Nucleoside diphosphate kinase. (153 aa)
W6QJA7_PENRFImidazolonepropionase. (462 aa)
W6QJE3_PENRFGenomic scaffold, ProqFM164S01. (332 aa)
W6QJJ2_PENRFUncharacterized protein. (343 aa)
ura-7CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (582 aa)
ADE1-2Bifunctional purine biosynthetic protein ADE1. (803 aa)
W6QLB3_PENRFProtein-tyrosine/Dual-specificity phosphatase. (310 aa)
W6QLE7_PENRF5'-Nucleotidase/apyrase; Belongs to the 5'-nucleotidase family. (665 aa)
ADE2Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (572 aa)
bsdBlasticidin-S deaminase. (131 aa)
ADE4Amidophosphoribosyltransferase. (579 aa)
W6QM41_PENRFGuanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (463 aa)
W6QM44_PENRFNudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. (204 aa)
ADE13Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (483 aa)
NUDT1Nudix hydrolase 1; Belongs to the Nudix hydrolase family. (150 aa)
W6QN07_PENRFAdenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (423 aa)
W6QNK8_PENRFUncharacterized protein. (91 aa)
gua1-2GMP synthase [glutamine-hydrolyzing]. (542 aa)
W6QNQ0_PENRFL-Aspartase-like. (111 aa)
PnpPurine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (317 aa)
W6QP65_PENRFThioredoxin; Belongs to the thioredoxin family. (106 aa)
W6QP82_PENRFHAD-superfamily hydrolase, subfamily IA, variant 3. (291 aa)
glr-1Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (474 aa)
W6QPP6_PENRFAldolase-type TIM barrel. (418 aa)
W6QTA0_PENRFTetratricopeptide-like helical. (567 aa)
W6PR92_PENRFGenomic scaffold, ProqFM164S01. (366 aa)
aah1Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (355 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (253 aa)
DUT1Deoxyuridine 5'-triphosphate nucleotidohydrolase. (188 aa)
CDC21Thymidylate synthase. (336 aa)
W6PU99_PENRFGenomic scaffold, ProqFM164S01. (118 aa)
W6PUR9_PENRFDihydroorotate dehydrogenase, class 1/ 2. (518 aa)
W6PV04_PENRFFlavoprotein. (231 aa)
W6PVT4_PENRFGenomic scaffold, ProqFM164S01. (258 aa)
fap7Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (177 aa)
W6PWJ5_PENRFAdenosine deaminase. (372 aa)
W6PYG6_PENRFOrotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. (259 aa)
W6PYW7_PENRFDeoxycytidylate deaminase. (352 aa)
ADE6Phosphoribosylformylglycinamidine synthase. (1360 aa)
W6PZE0_PENRFTetratricopeptide-like helical. (584 aa)
DTYMKThymidylate kinase. (201 aa)
APT1Adenine phosphoribosyltransferase. (203 aa)
ade5Phosphoribosylglycinamide formyltransferase. (223 aa)
W6Q0C3_PENRFPhosphoribosyltransferase. (1112 aa)
GUK1Guanylate kinase. (197 aa)
ada1AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (962 aa)
W6Q1J0_PENRFGenomic scaffold, ProqFM164S01. (246 aa)
W6Q1K1_PENRFInosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (184 aa)
CDACytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (138 aa)
W6Q222_PENRFTranscription factor, fungi. (494 aa)
W6Q239_PENRFGlutaredoxin, eukaryotic/virial. (272 aa)
HOR2(DL)-glycerol-3-phosphatase 2. (237 aa)
Your Current Organism:
Penicillium roqueforti
NCBI taxonomy Id: 1365484
Other names: P. roqueforti FM164, Penicillium roqueforti FM164
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