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PAN2 | PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent [...] (1429 aa) | ||||
V5ELL2_KALBG | EMC1_C domain-containing protein. (1121 aa) | ||||
V5ELQ3_KALBG | WD_REPEATS_REGION domain-containing protein. (474 aa) | ||||
V5ERJ6_KALBG | Putative periodic tryptophan protein PWP2. (902 aa) | ||||
V5EU56_KALBG | F-box domain-containing protein. (678 aa) | ||||
V5F125_KALBG | Uncharacterized protein. (1103 aa) | ||||
V5F305_KALBG | Uncharacterized protein. (1053 aa) | ||||
V5GHV0_KALBG | Uncharacterized protein. (543 aa) |