STRINGSTRING
AYL99_12023 AYL99_12023 AYL99_11744 AYL99_11744 AYL99_11420 AYL99_11420 AYL99_11472 AYL99_11472 AYL99_11082 AYL99_11082 AYL99_11146 AYL99_11146 AYL99_11155 AYL99_11155 AYL99_11270 AYL99_11270 AYL99_11730 AYL99_11730 AYL99_11356 AYL99_11356 AYL99_10792 AYL99_10792 AYL99_10802 AYL99_10802 AYL99_11091 AYL99_11091 AYL99_11013 AYL99_11013 AYL99_10317 AYL99_10317 AYL99_10070 AYL99_10070 AYL99_10100 AYL99_10100 AYL99_10151 AYL99_10151 AYL99_09248 AYL99_09248 AYL99_09389 AYL99_09389 AYL99_09501 AYL99_09501 AYL99_09541 AYL99_09541 AYL99_09345 AYL99_09345 AAH1 AAH1 AYL99_09977 AYL99_09977 AYL99_08819 AYL99_08819 AYL99_08840 AYL99_08840 AYL99_09030 AYL99_09030 AYL99_08728 AYL99_08728 AYL99_08685 AYL99_08685 AYL99_07938 AYL99_07938 AYL99_09205 AYL99_09205 AYL99_07978 AYL99_07978 AYL99_08010 AYL99_08010 AYL99_08945 AYL99_08945 AYL99_08175 AYL99_08175 AYL99_07974 AYL99_07974 AYL99_08287 AYL99_08287 AYL99_08044 AYL99_08044 AYL99_08548 AYL99_08548 ADK1 ADK1 AYL99_07369 AYL99_07369 AYL99_07232 AYL99_07232 AYL99_07106 AYL99_07106 AYL99_07524 AYL99_07524 AYL99_08581 AYL99_08581 AYL99_07371 AYL99_07371 AYL99_07153 AYL99_07153 AYL99_07085 AYL99_07085 AYL99_07711 AYL99_07711 AYL99_06266 AYL99_06266 AYL99_06435 AYL99_06435 AYL99_06293 AYL99_06293 AYL99_06667 AYL99_06667 AYL99_06858 AYL99_06858 AYL99_06977 AYL99_06977 AYL99_04910 AYL99_04910 AYL99_04951 AYL99_04951 AYL99_06651 AYL99_06651 AYL99_04854 AYL99_04854 AYL99_04914 AYL99_04914 AYL99_05289 AYL99_05289 AYL99_05301 AYL99_05301 AYL99_04958 AYL99_04958 AYL99_05386 AYL99_05386 AYL99_05093 AYL99_05093 AYL99_05486 AYL99_05486 AYL99_05556 AYL99_05556 ADK2 ADK2 AYL99_05851 AYL99_05851 AYL99_05860 AYL99_05860 AYL99_05573 AYL99_05573 AYL99_05911 AYL99_05911 AYL99_05949 AYL99_05949 AYL99_05217 AYL99_05217 AYL99_03380 AYL99_03380 AYL99_05778 AYL99_05778 AYL99_05675 AYL99_05675 AYL99_03510 AYL99_03510 AYL99_03357 AYL99_03357 AYL99_03907 AYL99_03907 AYL99_03825 AYL99_03825 AYL99_04141 AYL99_04141 AYL99_04207 AYL99_04207 AYL99_04262 AYL99_04262 AYL99_04297 AYL99_04297 AYL99_04321 AYL99_04321 AYL99_04457 AYL99_04457 AYL99_03999 AYL99_03999 AYL99_03906 AYL99_03906 AYL99_04543 AYL99_04543 AYL99_03946 AYL99_03946 AYL99_01771 AYL99_01771 AYL99_01795 AYL99_01795 AYL99_01801 AYL99_01801 AYL99_04296 AYL99_04296 AYL99_04556 AYL99_04556 AYL99_02261 AYL99_02261 AYL99_02291 AYL99_02291 AYL99_02295 AYL99_02295 AYL99_02354 AYL99_02354 AYL99_02613 AYL99_02613 AYL99_03207 AYL99_03207 AYL99_02462 AYL99_02462 AYL99_00039 AYL99_00039 AYL99_03148 AYL99_03148 AAH1-2 AAH1-2 AYL99_00689 AYL99_00689 AYL99_00932 AYL99_00932 AYL99_01020 AYL99_01020 AYL99_00515 AYL99_00515 AYL99_01459 AYL99_01459 AYL99_01680 AYL99_01680 AYL99_01208 AYL99_01208 AYL99_01223 AYL99_01223
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AYL99_12023Cytosine deaminase. (140 aa)
AYL99_11744Uncharacterized protein. (314 aa)
AYL99_11420Methionyl-tRNA formyltransferase. (385 aa)
AYL99_11472AB hydrolase-1 domain-containing protein. (378 aa)
AYL99_11082TIGR01456 family HAD hydrolase. (459 aa)
AYL99_11146Cytosine deaminase. (107 aa)
AYL99_11155Mur_ligase_M domain-containing protein. (458 aa)
AYL99_11270Formyltetrahydrofolate deformylase. (281 aa)
AYL99_11730IMPDH domain-containing protein. (243 aa)
AYL99_11356Dihydrofolate reductase. (272 aa)
AYL99_10792Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (230 aa)
AYL99_10802Bifunctional purine biosynthesis protein ADE17. (620 aa)
AYL99_11091Deoxyuridine 5'-triphosphate nucleotidohydrolase. (200 aa)
AYL99_11013RIBORED_LARGE domain-containing protein. (100 aa)
AYL99_10317Uncharacterized protein. (706 aa)
AYL99_10070GTP cyclohydrolase II. (428 aa)
AYL99_10100Nudix hydrolase domain-containing protein. (158 aa)
AYL99_10151Uncharacterized protein. (699 aa)
AYL99_09248AB hydrolase-1 domain-containing protein. (359 aa)
AYL99_09389F-box domain-containing protein. (648 aa)
AYL99_09501Uncharacterized protein. (740 aa)
AYL99_09541AB hydrolase-1 domain-containing protein. (574 aa)
AYL99_09345A_deaminase domain-containing protein. (613 aa)
AAH1Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (367 aa)
AYL99_09977Phosphoribosylaminoimidazolesuccinocarboxamide synthase. (306 aa)
AYL99_08819Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (200 aa)
AYL99_08840Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (531 aa)
AYL99_09030SET domain-containing protein. (188 aa)
AYL99_08728Peptidase A1 domain-containing protein; Belongs to the peptidase A1 family. (502 aa)
AYL99_08685Uncharacterized protein. (606 aa)
AYL99_07938Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (542 aa)
AYL99_09205DAO domain-containing protein. (466 aa)
AYL99_07978tRNA(Ile)-lysidine synthetase. (578 aa)
AYL99_08010IU_nuc_hydro domain-containing protein. (363 aa)
AYL99_08945Phosphoribosylamine-glycine ligase. (797 aa)
AYL99_08175Uncharacterized protein. (328 aa)
AYL99_07974Glutamine amidotransferase type-1 domain-containing protein. (255 aa)
AYL99_08287CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (259 aa)
AYL99_08044Pribosyltran domain-containing protein. (203 aa)
AYL99_08548CMP/dCMP-type deaminase domain-containing protein. (413 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (272 aa)
AYL99_07369Phosphoribosylaminoimidazole carboxylase, catalytic subunit. (185 aa)
AYL99_07232CMP/dCMP-type deaminase domain-containing protein. (315 aa)
AYL99_07106Uncharacterized protein. (743 aa)
AYL99_07524PH domain-containing protein. (1666 aa)
AYL99_08581CBFD_NFYB_HMF domain-containing protein. (78 aa)
AYL99_07371AB hydrolase-1 domain-containing protein. (420 aa)
AYL99_07153IU_nuc_hydro domain-containing protein. (369 aa)
AYL99_070853,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (240 aa)
AYL99_07711Uncharacterized protein. (299 aa)
AYL99_06266Uncharacterized protein. (938 aa)
AYL99_06435CMP/dCMP-type deaminase domain-containing protein. (213 aa)
AYL99_06293Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins; Belongs to the polypeptide deformylase family. (218 aa)
AYL99_06667Riboflavin synthase, alpha subunit. (254 aa)
AYL99_06858Adenine phosphoribosyltransferase. (214 aa)
AYL99_06977Uncharacterized protein. (335 aa)
AYL99_04910AB hydrolase-1 domain-containing protein. (327 aa)
AYL99_04951Dihydropteroate synthase. (472 aa)
AYL99_06651AB hydrolase-1 domain-containing protein. (370 aa)
AYL99_04854CMP/dCMP-type deaminase domain-containing protein. (265 aa)
AYL99_04914Metallophos domain-containing protein. (614 aa)
AYL99_05289Queuine tRNA-ribosyltransferase, variant 1. (292 aa)
AYL99_05301Thymidylate synthase. (383 aa)
AYL99_04958Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (393 aa)
AYL99_05386GRIP domain-containing protein. (591 aa)
AYL99_05093Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1068 aa)
AYL99_05486HD domain-containing protein. (280 aa)
AYL99_055563-carboxy-cis,cis-muconate cycloisomerase. (468 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (258 aa)
AYL99_05851Mur_ligase_M domain-containing protein. (504 aa)
AYL99_05860Guanylate kinase. (213 aa)
AYL99_05573RibD_C domain-containing protein. (683 aa)
AYL99_05911IU_nuc_hydro domain-containing protein. (433 aa)
AYL99_05949Flavoprotein domain-containing protein. (203 aa)
AYL99_05217AB hydrolase-1 domain-containing protein. (356 aa)
AYL99_03380PfkB domain-containing protein. (351 aa)
AYL99_05778Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (457 aa)
AYL99_05675CMP/dCMP-type deaminase domain-containing protein. (222 aa)
AYL99_03510Amidophosphoribosyltransferase. (595 aa)
AYL99_03357TIGR01456 family HAD hydrolase. (420 aa)
AYL99_03907Thymidylate kinase. (223 aa)
AYL99_03825DAO domain-containing protein. (678 aa)
AYL99_04141RED_N domain-containing protein. (513 aa)
AYL99_04207DHFR domain-containing protein; Belongs to the dihydrofolate reductase family. (490 aa)
AYL99_04262Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (604 aa)
AYL99_04297Uncharacterized protein. (130 aa)
AYL99_043216,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (228 aa)
AYL99_04457Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (507 aa)
AYL99_03999Putative GTP cyclohydrolase URC1. (498 aa)
AYL99_03906Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. (468 aa)
AYL99_04543Phosphoribosylglycinamide formyltransferase. (248 aa)
AYL99_03946GTP cyclohydrolase I. (356 aa)
AYL99_01771Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (173 aa)
AYL99_01795AB hydrolase-1 domain-containing protein. (265 aa)
AYL99_01801Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (572 aa)
AYL99_04296CMP/dCMP-type deaminase domain-containing protein. (291 aa)
AYL99_04556AB hydrolase-1 domain-containing protein. (299 aa)
AYL99_02261S4 RNA-binding domain-containing protein. (569 aa)
AYL99_02291GCV_T domain-containing protein. (421 aa)
AYL99_02295Ribonucleoside-diphosphate reductase small chain. (424 aa)
AYL99_02354Dihydroneopterin aldolase. (264 aa)
AYL99_026133-carboxy-cis,cis-muconate cycloisomerase. (454 aa)
AYL99_03207Uncharacterized protein. (365 aa)
AYL99_02462Uncharacterized protein. (420 aa)
AYL99_00039Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (549 aa)
AYL99_03148AB hydrolase-1 domain-containing protein. (354 aa)
AAH1-2Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (331 aa)
AYL99_00689Uncharacterized protein. (445 aa)
AYL99_00932GMP synthase. (547 aa)
AYL99_01020Uncharacterized protein. (296 aa)
AYL99_00515Coronin; Belongs to the WD repeat coronin family. (597 aa)
AYL99_01459Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (476 aa)
AYL99_01680Phosphoribosylformylglycinamidine synthase. (1385 aa)
AYL99_01208Uncharacterized protein. (788 aa)
AYL99_01223Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (483 aa)
Your Current Organism:
Fonsecaea erecta
NCBI taxonomy Id: 1367422
Other names: F. erecta, Fonsecaea erecta V. A. Vicente, Najafzadeh, Sun & de Hoog 2013, Fonsecaea sp. RG-2013a
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