7 items (Fonsecaea erecta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AYL99_02042	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2917 aa)
	AYL99_12028	BZIP domain-containing protein. (129 aa)
	AYL99_05600	BZIP domain-containing protein. (434 aa)
	AYL99_01398	Ubiquitin-40S ribosomal protein S27a. (154 aa)
	AYL99_06194	Uncharacterized protein. (812 aa)
	AYL99_02996	Polyubiquitin. (229 aa)
	AYL99_02765	TPR_REGION domain-containing protein. (616 aa)

Your Current Organism:

Fonsecaea erecta

NCBI taxonomy Id: 1367422
Other names: F. erecta, Fonsecaea erecta V. A. Vicente, Najafzadeh, Sun & de Hoog 2013, Fonsecaea sp. RG-2013a

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AYL99_01398	AYL99_02765	A0A179A1K2	A0A178ZUT5	Ubiquitin-40S ribosomal protein S27a.	TPR_REGION domain-containing protein.	0.718
AYL99_01398	AYL99_02996	A0A179A1K2	A0A178ZVH7	Ubiquitin-40S ribosomal protein S27a.	Polyubiquitin.	0.964
AYL99_01398	AYL99_06194	A0A179A1K2	A0A178ZGH7	Ubiquitin-40S ribosomal protein S27a.	Uncharacterized protein.	0.852
AYL99_02042	AYL99_02765	A0A178ZUQ8	A0A178ZUT5	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.	TPR_REGION domain-containing protein.	0.987
AYL99_02042	AYL99_02996	A0A178ZUQ8	A0A178ZVH7	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.	Polyubiquitin.	0.663
AYL99_02765	AYL99_01398	A0A178ZUT5	A0A179A1K2	TPR_REGION domain-containing protein.	Ubiquitin-40S ribosomal protein S27a.	0.718
AYL99_02765	AYL99_02042	A0A178ZUT5	A0A178ZUQ8	TPR_REGION domain-containing protein.	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.	0.987
AYL99_02765	AYL99_02996	A0A178ZUT5	A0A178ZVH7	TPR_REGION domain-containing protein.	Polyubiquitin.	0.790
AYL99_02765	AYL99_05600	A0A178ZUT5	A0A178ZLB9	TPR_REGION domain-containing protein.	BZIP domain-containing protein.	0.718
AYL99_02765	AYL99_06194	A0A178ZUT5	A0A178ZGH7	TPR_REGION domain-containing protein.	Uncharacterized protein.	0.754
AYL99_02765	AYL99_12028	A0A178ZUT5	A0A178Z1U9	TPR_REGION domain-containing protein.	BZIP domain-containing protein.	0.718
AYL99_02996	AYL99_01398	A0A178ZVH7	A0A179A1K2	Polyubiquitin.	Ubiquitin-40S ribosomal protein S27a.	0.964
AYL99_02996	AYL99_02042	A0A178ZVH7	A0A178ZUQ8	Polyubiquitin.	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.	0.663
AYL99_02996	AYL99_02765	A0A178ZVH7	A0A178ZUT5	Polyubiquitin.	TPR_REGION domain-containing protein.	0.790
AYL99_02996	AYL99_05600	A0A178ZVH7	A0A178ZLB9	Polyubiquitin.	BZIP domain-containing protein.	0.950
AYL99_02996	AYL99_06194	A0A178ZVH7	A0A178ZGH7	Polyubiquitin.	Uncharacterized protein.	0.834
AYL99_02996	AYL99_12028	A0A178ZVH7	A0A178Z1U9	Polyubiquitin.	BZIP domain-containing protein.	0.950
AYL99_05600	AYL99_02765	A0A178ZLB9	A0A178ZUT5	BZIP domain-containing protein.	TPR_REGION domain-containing protein.	0.718
AYL99_05600	AYL99_02996	A0A178ZLB9	A0A178ZVH7	BZIP domain-containing protein.	Polyubiquitin.	0.950
AYL99_05600	AYL99_06194	A0A178ZLB9	A0A178ZGH7	BZIP domain-containing protein.	Uncharacterized protein.	0.852