STRINGSTRING
AYL99_06687 AYL99_06687 AYL99_10987 AYL99_10987 AYL99_11730 AYL99_11730 AYL99_10657 AYL99_10657 AYL99_10669 AYL99_10669 AYL99_11396 AYL99_11396 AYL99_10730 AYL99_10730 AYL99_11516 AYL99_11516 AYL99_10802 AYL99_10802 AYL99_10908 AYL99_10908 AYL99_10917 AYL99_10917 AYL99_10207 AYL99_10207 AYL99_11013 AYL99_11013 AYL99_10823 AYL99_10823 AYL99_10100 AYL99_10100 AYL99_09286 AYL99_09286 AYL99_09250 AYL99_09250 AYL99_09501 AYL99_09501 AYL99_09345 AYL99_09345 AAH1 AAH1 AYL99_09977 AYL99_09977 AYL99_09302 AYL99_09302 AYL99_08819 AYL99_08819 AYL99_08743 AYL99_08743 AYL99_08818 AYL99_08818 AYL99_07855 AYL99_07855 AYL99_08685 AYL99_08685 AYL99_07938 AYL99_07938 AYL99_09053 AYL99_09053 AYL99_08012 AYL99_08012 AYL99_08020 AYL99_08020 AYL99_08945 AYL99_08945 AYL99_08927 AYL99_08927 AYL99_07974 AYL99_07974 AYL99_08977 AYL99_08977 AYL99_08044 AYL99_08044 AYL99_09156 AYL99_09156 AYL99_08446 AYL99_08446 AYL99_07911 AYL99_07911 AYL99_08642 AYL99_08642 ADK1 ADK1 AYL99_07058 AYL99_07058 AYL99_08429 AYL99_08429 AYL99_07229 AYL99_07229 AYL99_07284 AYL99_07284 AYL99_07330 AYL99_07330 AYL99_07369 AYL99_07369 AYL99_07422 AYL99_07422 AYL99_07371 AYL99_07371 AYL99_07481 AYL99_07481 AYL99_07692 AYL99_07692 AYL99_07691 AYL99_07691 AYL99_07375 AYL99_07375 AYL99_07836 AYL99_07836 AYL99_06530 AYL99_06530 AYL99_06697 AYL99_06697 AYL99_06449 AYL99_06449 AYL99_06858 AYL99_06858 AYL99_06669 AYL99_06669 AYL99_06561 AYL99_06561 AYL99_06651 AYL99_06651 AYL99_06533 AYL99_06533 AYL99_04914 AYL99_04914 AYL99_05072 AYL99_05072 AYL99_06761 AYL99_06761 AYL99_06663 AYL99_06663 AYL99_06853 AYL99_06853 AYL99_05386 AYL99_05386 AYL99_06983 AYL99_06983 AYL99_05556 AYL99_05556 AYL99_05238 AYL99_05238 ADK2 ADK2 AYL99_05762 AYL99_05762 AYL99_05860 AYL99_05860 MET3 MET3 AYL99_05485 AYL99_05485 AYL99_03380 AYL99_03380 AYL99_05778 AYL99_05778 AYL99_03421 AYL99_03421 AYL99_03420 AYL99_03420 AYL99_03408 AYL99_03408 AYL99_05828 AYL99_05828 AYL99_03510 AYL99_03510 AYL99_06017 AYL99_06017 AYL99_05827 AYL99_05827 AYL99_04003 AYL99_04003 AYL99_03905 AYL99_03905 AYL99_04117 AYL99_04117 AYL99_04182 AYL99_04182 AYL99_03749 AYL99_03749 AYL99_04262 AYL99_04262 AYL99_04085 AYL99_04085 AYL99_03796 AYL99_03796 AYL99_04543 AYL99_04543 AYL99_01801 AYL99_01801 AYL99_04655 AYL99_04655 AYL99_01997 AYL99_01997 AYL99_02295 AYL99_02295 AYL99_02547 AYL99_02547 AYL99_02574 AYL99_02574 AYL99_02825 AYL99_02825 AYL99_02300 AYL99_02300 AYL99_02907 AYL99_02907 AYL99_02410 AYL99_02410 AYL99_02613 AYL99_02613 AYL99_00039 AYL99_00039 AYL99_02940 AYL99_02940 AYL99_00340 AYL99_00340 AAH1-2 AAH1-2 AYL99_02822 AYL99_02822 AYL99_00015 AYL99_00015 AYL99_00268 AYL99_00268 AYL99_00932 AYL99_00932 AYL99_00890 AYL99_00890 AYL99_00247 AYL99_00247 AYL99_00633 AYL99_00633 AYL99_01466 AYL99_01466 AYL99_01401 AYL99_01401 AYL99_01680 AYL99_01680 AYL99_01223 AYL99_01223 AYL99_01288 AYL99_01288 AYL99_01598 AYL99_01598 AYL99_01575 AYL99_01575
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AYL99_06687Uncharacterized protein. (180 aa)
AYL99_109875'/3'-nucleotidase SurE. (359 aa)
AYL99_11730IMPDH domain-containing protein. (243 aa)
AYL99_10657Glutamine amidotransferase type-1 domain-containing protein. (300 aa)
AYL99_10669Diphthami_syn_2 domain-containing protein. (870 aa)
AYL99_11396Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (912 aa)
AYL99_10730Pribosyltran_N domain-containing protein. (533 aa)
AYL99_11516Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (225 aa)
AYL99_10802Bifunctional purine biosynthesis protein ADE17. (620 aa)
AYL99_10908CN hydrolase domain-containing protein. (297 aa)
AYL99_10917Uncharacterized protein. (387 aa)
AYL99_10207OBG-type G domain-containing protein. (416 aa)
AYL99_11013RIBORED_LARGE domain-containing protein. (100 aa)
AYL99_10823Amidohydro-rel domain-containing protein. (494 aa)
AYL99_10100Nudix hydrolase domain-containing protein. (158 aa)
AYL99_09286Uncharacterized protein. (108 aa)
AYL99_09250Uncharacterized protein. (2058 aa)
AYL99_09501Uncharacterized protein. (740 aa)
AYL99_09345A_deaminase domain-containing protein. (613 aa)
AAH1Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (367 aa)
AYL99_09977Phosphoribosylaminoimidazolesuccinocarboxamide synthase. (306 aa)
AYL99_09302Uncharacterized protein. (158 aa)
AYL99_08819Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (200 aa)
AYL99_08743Importin N-terminal domain-containing protein. (1009 aa)
AYL99_08818Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (193 aa)
AYL99_07855Fungal_trans domain-containing protein. (588 aa)
AYL99_08685Uncharacterized protein. (606 aa)
AYL99_07938Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (542 aa)
AYL99_09053Uncharacterized protein. (627 aa)
AYL99_08012Guanine deaminase. (486 aa)
AYL99_08020Uncharacterized protein. (277 aa)
AYL99_08945Phosphoribosylamine-glycine ligase. (797 aa)
AYL99_08927Nudix hydrolase domain-containing protein. (228 aa)
AYL99_07974Glutamine amidotransferase type-1 domain-containing protein. (255 aa)
AYL99_08977Nudix hydrolase domain-containing protein. (307 aa)
AYL99_08044Pribosyltran domain-containing protein. (203 aa)
AYL99_09156Uncharacterized protein. (145 aa)
AYL99_08446Metallophos domain-containing protein. (415 aa)
AYL99_07911Uncharacterized protein. (268 aa)
AYL99_08642Uncharacterized protein. (531 aa)
ADK1Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (272 aa)
AYL99_07058Uncharacterized protein. (329 aa)
AYL99_08429Nucleoside diphosphate kinase. (154 aa)
AYL99_07229F-box domain-containing protein. (747 aa)
AYL99_07284Pribosyltran_N domain-containing protein. (371 aa)
AYL99_07330tRNA pseudouridine(38-40) synthase, variant. (650 aa)
AYL99_07369Phosphoribosylaminoimidazole carboxylase, catalytic subunit. (185 aa)
AYL99_07422Uncharacterized protein. (897 aa)
AYL99_07371AB hydrolase-1 domain-containing protein. (420 aa)
AYL99_07481Uncharacterized protein. (460 aa)
AYL99_07692Uncharacterized protein. (542 aa)
AYL99_07691Urease; In the C-terminal section; belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. (826 aa)
AYL99_07375Pribosyltran_N domain-containing protein. (319 aa)
AYL99_07836Guanine deaminase. (475 aa)
AYL99_06530tRNA pseudouridine(38-40) synthase. (667 aa)
AYL99_066975'/3'-nucleotidase SurE. (753 aa)
AYL99_06449MFS domain-containing protein. (527 aa)
AYL99_06858Adenine phosphoribosyltransferase. (214 aa)
AYL99_06669Allantoicase. (394 aa)
AYL99_06561Uncharacterized protein. (522 aa)
AYL99_06651AB hydrolase-1 domain-containing protein. (370 aa)
AYL99_06533Pribosyltran_N domain-containing protein. (452 aa)
AYL99_04914Metallophos domain-containing protein. (614 aa)
AYL99_05072Guanylate cyclase domain-containing protein. (281 aa)
AYL99_06761VOC domain-containing protein. (133 aa)
AYL99_06663Uncharacterized protein. (523 aa)
AYL99_06853Phosphodiesterase. (1051 aa)
AYL99_05386GRIP domain-containing protein. (591 aa)
AYL99_06983Xanthine dehydrogenase. (1363 aa)
AYL99_055563-carboxy-cis,cis-muconate cycloisomerase. (468 aa)
AYL99_05238Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Belongs to the uricase family. (304 aa)
ADK2GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (258 aa)
AYL99_05762HIT domain-containing protein. (266 aa)
AYL99_05860Guanylate kinase. (213 aa)
MET3Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the N-terminal section; belongs to the sulfate adenylyltransferase family. (573 aa)
AYL99_05485Bis(5'-adenosyl)-triphosphatase. (208 aa)
AYL99_03380PfkB domain-containing protein. (351 aa)
AYL99_05778Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (457 aa)
AYL99_03421DBINO domain-containing protein. (773 aa)
AYL99_03420Adenosinetriphosphatase. (891 aa)
AYL99_03408Uncharacterized protein; Belongs to the 5'-nucleotidase family. (627 aa)
AYL99_05828Uncharacterized protein. (161 aa)
AYL99_03510Amidophosphoribosyltransferase. (595 aa)
AYL99_06017Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. (393 aa)
AYL99_05827Uncharacterized protein. (126 aa)
AYL99_04003Pribosyltran_N domain-containing protein. (304 aa)
AYL99_03905DHHA2 domain-containing protein. (556 aa)
AYL99_04117NTP_transf_9 domain-containing protein. (101 aa)
AYL99_04182Uncharacterized protein. (451 aa)
AYL99_03749CutC domain-containing protein. (224 aa)
AYL99_04262Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (604 aa)
AYL99_04085Metallophos domain-containing protein. (614 aa)
AYL99_03796Guanine deaminase. (484 aa)
AYL99_04543Phosphoribosylglycinamide formyltransferase. (248 aa)
AYL99_01801Uncharacterized protein; Belongs to the GDA1/CD39 NTPase family. (572 aa)
AYL99_04655Pyruvate kinase; Belongs to the pyruvate kinase family. (524 aa)
AYL99_01997Uncharacterized protein. (678 aa)
AYL99_02295Ribonucleoside-diphosphate reductase small chain. (424 aa)
AYL99_02547Uncharacterized protein. (216 aa)
AYL99_02574Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. (208 aa)
AYL99_02825ATP_transf domain-containing protein. (350 aa)
AYL99_02300OHCU_decarbox domain-containing protein. (156 aa)
AYL99_02907AMP deaminase. (1080 aa)
AYL99_02410Phosphoglucomutase; Belongs to the phosphohexose mutase family. (555 aa)
AYL99_026133-carboxy-cis,cis-muconate cycloisomerase. (454 aa)
AYL99_00039Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (549 aa)
AYL99_02940MFS domain-containing protein. (533 aa)
AYL99_00340TAF4 domain-containing protein. (571 aa)
AAH1-2Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. (331 aa)
AYL99_02822Uncharacterized protein. (522 aa)
AYL99_00015Uncharacterized protein. (1341 aa)
AYL99_00268Uncharacterized protein. (617 aa)
AYL99_00932GMP synthase. (547 aa)
AYL99_00890Amidohydro-rel domain-containing protein. (479 aa)
AYL99_00247Uncharacterized protein. (434 aa)
AYL99_00633Zn(2)-C6 fungal-type domain-containing protein. (729 aa)
AYL99_01466Nudix hydrolase domain-containing protein. (402 aa)
AYL99_014015-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (130 aa)
AYL99_01680Phosphoribosylformylglycinamidine synthase. (1385 aa)
AYL99_01223Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (483 aa)
AYL99_01288Allantoinase. (551 aa)
AYL99_01598HIT domain-containing protein. (133 aa)
AYL99_01575Uncharacterized protein. (1123 aa)
Your Current Organism:
Fonsecaea erecta
NCBI taxonomy Id: 1367422
Other names: F. erecta, Fonsecaea erecta V. A. Vicente, Najafzadeh, Sun & de Hoog 2013, Fonsecaea sp. RG-2013a
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.