(118 nodes) Biosynthesis of unsaturated fatty acids network (Fonsecaea erecta)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AYL99_05429	Putative MFS-type transporter. (504 aa)
	AYL99_00667	Uncharacterized protein. (245 aa)
	AYL99_01088	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (459 aa)
	AYL99_01511	Cytochrome b5 heme-binding domain-containing protein. (569 aa)
	AYL99_01660	MFS domain-containing protein. (522 aa)
	AYL99_01756	MFS domain-containing protein. (513 aa)
	AYL99_01679	Elongation of fatty acids protein. (346 aa)
	AYL99_01298	MFS domain-containing protein. (533 aa)
	AYL99_01305	MFS domain-containing protein. (598 aa)
	AYL99_00996	F-box domain-containing protein. (1204 aa)
	AYL99_00952	MFS domain-containing protein. (618 aa)
	AYL99_00205	AB hydrolase-1 domain-containing protein. (401 aa)
	AYL99_00570	Uncharacterized protein. (90 aa)
	AYL99_02982	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (412 aa)
	AYL99_03250	BZIP domain-containing protein. (318 aa)
	AYL99_00284	SCP2 domain-containing protein. (131 aa)
	AYL99_00279	MFS domain-containing protein. (616 aa)
	AYL99_00089	BZIP domain-containing protein. (239 aa)
	AYL99_03028	MFS domain-containing protein. (498 aa)
	AYL99_02532	MFS domain-containing protein. (510 aa)
	AYL99_02780	Uncharacterized protein. (563 aa)
	AYL99_03209	BZIP domain-containing protein. (237 aa)
	AYL99_03211	BZIP domain-containing protein. (234 aa)
	AYL99_03171	MFS domain-containing protein. (576 aa)
	AYL99_02818	Uncharacterized protein. (511 aa)
	AYL99_02523	MFS domain-containing protein. (552 aa)
	AYL99_02779	Uncharacterized protein. (874 aa)
	AYL99_02493	MFS domain-containing protein. (537 aa)
	AYL99_02707	MFS domain-containing protein. (595 aa)
	AYL99_02657	MFS domain-containing protein. (488 aa)
	AYL99_02060	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (234 aa)
	AYL99_02529	Uncharacterized protein. (290 aa)
	AYL99_02201	BZIP domain-containing protein. (241 aa)
	AYL99_04308	Uncharacterized protein. (414 aa)
	AYL99_04128	MFS domain-containing protein. (543 aa)
	AYL99_04539	Uncharacterized protein. (274 aa)
	AYL99_01877	Uncharacterized protein. (232 aa)
	AYL99_04399	Hydrolase_4 domain-containing protein. (292 aa)
	AYL99_04719	MFS domain-containing protein. (534 aa)
	AYL99_04129	Zn(2)-C6 fungal-type domain-containing protein. (698 aa)
	AYL99_03836	Zn(2)-C6 fungal-type domain-containing protein. (729 aa)
	AYL99_04074	MFS domain-containing protein. (486 aa)
	AYL99_03696	MFS domain-containing protein. (492 aa)
	AYL99_03266	MFS domain-containing protein. (618 aa)
	AYL99_03855	MFS domain-containing protein. (606 aa)
	AYL99_03942	MFS domain-containing protein. (554 aa)
	AYL99_03575	MFS domain-containing protein. (627 aa)
	AYL99_05925	MFS domain-containing protein. (557 aa)
	AYL99_03565	Uncharacterized protein. (457 aa)
	AYL99_05717	BZIP domain-containing protein. (213 aa)
	AYL99_03545	MFS domain-containing protein. (498 aa)
	AYL99_06000	Hemerythrin domain-containing protein. (187 aa)
	AYL99_03631	BZIP domain-containing protein. (243 aa)
	AYL99_03388	MFS domain-containing protein. (542 aa)
	AYL99_06044	MFS domain-containing protein. (632 aa)
	AYL99_06038	Zn(2)-C6 fungal-type domain-containing protein. (254 aa)
	AYL99_05998	Uncharacterized protein. (337 aa)
	AYL99_05563	MFS domain-containing protein. (502 aa)
	AYL99_05368	Uncharacterized protein. (379 aa)
	AYL99_04797	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. (338 aa)
	AYL99_01023	BZIP domain-containing protein. (244 aa)
	AYL99_04833	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (480 aa)
	AYL99_06621	MFS domain-containing protein. (520 aa)
	AYL99_04784	Acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (409 aa)
	AYL99_06848	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (457 aa)
	AYL99_06556	Uncharacterized protein. (553 aa)
	AYL99_06495	MFS domain-containing protein. (497 aa)
	AYL99_06311	MFS domain-containing protein. (641 aa)
	AYL99_06116	MFS domain-containing protein. (505 aa)
	AYL99_07263	S5A_REDUCTASE domain-containing protein. (333 aa)
	AYL99_07694	Uncharacterized protein. (292 aa)
	AYL99_07341	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (707 aa)
	AYL99_07548	Uncharacterized protein. (306 aa)
	AYL99_07458	MFS domain-containing protein. (557 aa)
	AYL99_08251	MFS domain-containing protein. (785 aa)
	AYL99_07169	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (421 aa)
	AYL99_07100	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (634 aa)
	AYL99_08645	FA_desaturase domain-containing protein. (480 aa)
	AYL99_08189	MFS transporter, DHA1 family, multidrug resistance protein. (481 aa)
	AYL99_08435	MFS domain-containing protein. (547 aa)
	AYL99_08397	Uncharacterized protein. (233 aa)
	AYL99_09075	Uncharacterized protein. (299 aa)
	AYL99_08002	BZIP domain-containing protein. (234 aa)
	AYL99_09163	AB hydrolase-1 domain-containing protein. (305 aa)
	AYL99_09484	MFS domain-containing protein. (502 aa)
	AYL99_08920	Uncharacterized protein. (707 aa)
	AYL99_10027	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
	AYL99_09577	Beta-xylanase. (415 aa)
	AYL99_09558	MFS domain-containing protein. (552 aa)
	AYL99_09341	Elongation of fatty acids protein. (853 aa)
	AYL99_09246	Uncharacterized protein. (302 aa)
	AYL99_10278	MFS domain-containing protein. (571 aa)
	AYL99_09939	Uncharacterized protein. (296 aa)
	AYL99_10893	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (624 aa)
	AYL99_10873	AB hydrolase-1 domain-containing protein. (394 aa)
	AYL99_10294	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (416 aa)
	AYL99_10907	MFS domain-containing protein. (530 aa)
	AYL99_10897	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (689 aa)
	AYL99_10822	Zn(2)-C6 fungal-type domain-containing protein. (696 aa)
	AYL99_10874	Uncharacterized protein. (1360 aa)
	AYL99_10849	Uncharacterized protein. (304 aa)
	AYL99_10732	Uncharacterized protein. (537 aa)
	AYL99_10648	MFS domain-containing protein. (565 aa)
	AYL99_11202	BZIP domain-containing protein. (640 aa)
	AYL99_11057	Uncharacterized protein. (936 aa)
	AYL99_10937	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (680 aa)
	AYL99_11539	Zn(2)-C6 fungal-type domain-containing protein. (832 aa)
	AYL99_11380	AB hydrolase-1 domain-containing protein. (687 aa)
	AYL99_11369	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (460 aa)
	AYL99_11623	Uncharacterized protein. (110 aa)
	AYL99_00197	MFS domain-containing protein. (655 aa)
	AYL99_00503	MFS domain-containing protein. (508 aa)
	AYL99_00638	MFS domain-containing protein. (565 aa)
	AYL99_01210	Uncharacterized protein. (236 aa)
	AYL99_01104	Uncharacterized protein. (314 aa)
	AYL99_00417	MFS domain-containing protein. (630 aa)
	AYL99_01382	MFS domain-containing protein. (616 aa)
	AYL99_01486	Uncharacterized protein. (377 aa)

Your Current Organism:

Fonsecaea erecta

NCBI taxonomy Id: 1367422
Other names: F. erecta, Fonsecaea erecta V. A. Vicente, Najafzadeh, Sun & de Hoog 2013, Fonsecaea sp. RG-2013a

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AYL99_00089	AYL99_00667	A0A178ZWP6	A0A179A0D9	BZIP domain-containing protein.	Uncharacterized protein.	0.601
AYL99_00089	AYL99_01104	A0A178ZWP6	A0A178ZZH9	BZIP domain-containing protein.	Uncharacterized protein.	0.569
AYL99_00089	AYL99_01511	A0A178ZWP6	A0A179A0I5	BZIP domain-containing protein.	Cytochrome b5 heme-binding domain-containing protein.	0.474
AYL99_00089	AYL99_01679	A0A178ZWP6	A0A179A135	BZIP domain-containing protein.	Elongation of fatty acids protein.	0.555
AYL99_00089	AYL99_01877	A0A178ZWP6	A0A178ZS54	BZIP domain-containing protein.	Uncharacterized protein.	0.601
AYL99_00089	AYL99_04539	A0A178ZWP6	A0A178ZSG6	BZIP domain-containing protein.	Uncharacterized protein.	0.601
AYL99_00089	AYL99_04797	A0A178ZWP6	A0A178ZL87	BZIP domain-containing protein.	Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.	0.722
AYL99_00089	AYL99_04833	A0A178ZWP6	A0A178ZK22	BZIP domain-containing protein.	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	0.764
AYL99_00089	AYL99_07263	A0A178ZWP6	A0A178ZG55	BZIP domain-containing protein.	S5A_REDUCTASE domain-containing protein.	0.855
AYL99_00089	AYL99_08397	A0A178ZWP6	A0A178ZD13	BZIP domain-containing protein.	Uncharacterized protein.	0.601
AYL99_00089	AYL99_09341	A0A178ZWP6	A0A178Z911	BZIP domain-containing protein.	Elongation of fatty acids protein.	0.455
AYL99_00197	AYL99_04833	A0A178ZYX7	A0A178ZK22	MFS domain-containing protein.	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	0.548
AYL99_00205	AYL99_01088	A0A178ZYC5	A0A179A0I0	AB hydrolase-1 domain-containing protein.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.771
AYL99_00205	AYL99_03565	A0A178ZYC5	A0A178ZNY4	AB hydrolase-1 domain-containing protein.	Uncharacterized protein.	0.504
AYL99_00205	AYL99_06848	A0A178ZYC5	A0A178ZIE6	AB hydrolase-1 domain-containing protein.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.771
AYL99_00205	AYL99_11369	A0A178ZYC5	A0A178Z3B2	AB hydrolase-1 domain-containing protein.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.771
AYL99_00279	AYL99_04833	A0A178ZX89	A0A178ZK22	MFS domain-containing protein.	Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.	0.548
AYL99_00284	AYL99_01088	A0A178ZX91	A0A179A0I0	SCP2 domain-containing protein.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.597
AYL99_00284	AYL99_02982	A0A178ZX91	A0A178ZXN1	SCP2 domain-containing protein.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.664
AYL99_00284	AYL99_04784	A0A178ZX91	A0A178ZJD3	SCP2 domain-containing protein.	Acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.664