(13 nodes) C-X-C chemokine receptor activity, and Chemokine activity network (Pelodiscus sinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CXCR5	C-X-C motif chemokine receptor 5. (231 aa)
	LOC102452532	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (356 aa)
	CCR4	C-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (358 aa)
	CCR7	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (377 aa)
	LOC102463217	C-C motif chemokine. (91 aa)
	LOC102463449	C-C motif chemokine. (93 aa)
	CCL5	C-C motif chemokine ligand 5. (90 aa)
	CXCR6	C-X-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (312 aa)
	K7FNS9_PELSI	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (362 aa)
	CXCR4	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (427 aa)
	CXCL12	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (89 aa)
	CXCR3	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (374 aa)
	ACKR3	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (364 aa)

Your Current Organism:

Pelodiscus sinensis

NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACKR3	CXCL12	ENSPSIP00000020039	ENSPSIP00000016913	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	0.996
ACKR3	CXCR4	ENSPSIP00000020039	ENSPSIP00000009723	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	0.900
ACKR3	CXCR5	ENSPSIP00000020039	ENSPSIP00000000459	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine receptor 5.	0.504
ACKR3	CXCR6	ENSPSIP00000020039	ENSPSIP00000009622	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family.	0.419
ACKR3	LOC102452532	ENSPSIP00000020039	ENSPSIP00000001003	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.464
CCL5	CCR4	ENSPSIP00000005808	ENSPSIP00000001247	C-C motif chemokine ligand 5.	C-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	0.989
CCL5	CCR7	ENSPSIP00000005808	ENSPSIP00000002562	C-C motif chemokine ligand 5.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.814
CCL5	CXCL12	ENSPSIP00000005808	ENSPSIP00000016913	C-C motif chemokine ligand 5.	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	0.976
CCL5	CXCR3	ENSPSIP00000005808	ENSPSIP00000019806	C-C motif chemokine ligand 5.	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.715
CCL5	CXCR4	ENSPSIP00000005808	ENSPSIP00000009723	C-C motif chemokine ligand 5.	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	0.805
CCL5	CXCR5	ENSPSIP00000005808	ENSPSIP00000000459	C-C motif chemokine ligand 5.	C-X-C motif chemokine receptor 5.	0.740
CCL5	CXCR6	ENSPSIP00000005808	ENSPSIP00000009622	C-C motif chemokine ligand 5.	C-X-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family.	0.705
CCL5	K7FNS9_PELSI	ENSPSIP00000005808	ENSPSIP00000009689	C-C motif chemokine ligand 5.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.985
CCL5	LOC102452532	ENSPSIP00000005808	ENSPSIP00000001003	C-C motif chemokine ligand 5.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.743
CCL5	LOC102463449	ENSPSIP00000005808	ENSPSIP00000005787	C-C motif chemokine ligand 5.	C-C motif chemokine.	0.589
CCR4	CCL5	ENSPSIP00000001247	ENSPSIP00000005808	C-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine ligand 5.	0.989
CCR4	CCR7	ENSPSIP00000001247	ENSPSIP00000002562	C-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.720
CCR4	CXCL12	ENSPSIP00000001247	ENSPSIP00000016913	C-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	0.711
CCR4	CXCR3	ENSPSIP00000001247	ENSPSIP00000019806	C-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.523
CCR4	CXCR4	ENSPSIP00000001247	ENSPSIP00000009723	C-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	0.706