(41 nodes) CORVET complex, and Rab regulation of trafficking network (Pelodiscus sinensis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RAB9A	RAB9A, member RAS oncogene family. (201 aa)
	RAB9B	RAB9B, member RAS oncogene family. (201 aa)
	RABEP2	Rabaptin, RAB GTPase binding effector protein 2. (428 aa)
	RAB5B	RAB5B, member RAS oncogene family. (217 aa)
	VPS11	Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (877 aa)
	GAPVD1	GTPase activating protein and VPS9 domains 1. (1461 aa)
	RMC1	Regulator of MON1-CCZ1. (656 aa)
	RABGEF1	Uncharacterized protein. (578 aa)
	GGA2	Golgi associated, gamma adaptin ear containing, ARF binding protein 2. (580 aa)
	RAB5A	RAB5A, member RAS oncogene family. (215 aa)
	RABEP1	Rabaptin, RAB GTPase binding effector protein 1. (860 aa)
	VPS45	Vacuolar protein sorting 45 homolog; Belongs to the STXBP/unc-18/SEC1 family. (570 aa)
	RBSN	Rabenosyn, RAB effector. (788 aa)
	VPS39	VPS39 subunit of HOPS complex. (865 aa)
	RAB19	RAB19, member RAS oncogene family. (215 aa)
	K7FQH3_PELSI	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (815 aa)
	MON1B	MON1 homolog B, secretory trafficking associated. (436 aa)
	GGA1	Golgi associated, gamma adaptin ear containing, ARF binding protein 1. (660 aa)
	GCC2	GRIP and coiled-coil domain containing 2. (1667 aa)
	VAMP7	Vesicle associated membrane protein 7; Belongs to the synaptobrevin family. (220 aa)
	ANKRD27	Ankyrin repeat domain 27. (1065 aa)
	LOC102444442	Uncharacterized protein. (252 aa)
	VPS33A	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (569 aa)
	K7G3G9_PELSI	Uncharacterized protein. (468 aa)
	USP6NL	USP6 N-terminal like. (842 aa)
	CCZ1	Uncharacterized protein. (482 aa)
	VPS18	VPS18 core subunit of CORVET and HOPS complexes. (974 aa)
	LOC102457209	Rab-GAP TBC domain-containing protein. (401 aa)
	ZFAND5	Zinc finger AN1-type containing 5. (211 aa)
	RAB5C	Uncharacterized protein. (216 aa)
	RABGAP1L	RAB GTPase activating protein 1 like. (1058 aa)
	RAB20	RAB20, member RAS oncogene family. (234 aa)
	TGFBRAP1	Transforming growth factor beta receptor associated protein 1. (875 aa)
	TSNARE1	t-SNARE domain containing 1. (218 aa)
	PLEKHM2	Pleckstrin homology and RUN domain containing M2. (901 aa)
	TBC1D2B	TBC1 domain family member 2B. (841 aa)
	K7GFP1_PELSI	Uncharacterized protein. (296 aa)
	RAB17	RAB17, member RAS oncogene family. (237 aa)
	VPS8	RING-type domain-containing protein. (861 aa)
	VPS41	Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (854 aa)
	EEA1	Early endosome antigen 1. (1409 aa)

Your Current Organism:

Pelodiscus sinensis

NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD27	GGA1	ENSPSIP00000013838	ENSPSIP00000010903	Ankyrin repeat domain 27.	Golgi associated, gamma adaptin ear containing, ARF binding protein 1.	0.485
ANKRD27	GGA2	ENSPSIP00000013838	ENSPSIP00000007523	Ankyrin repeat domain 27.	Golgi associated, gamma adaptin ear containing, ARF binding protein 2.	0.485
ANKRD27	RAB17	ENSPSIP00000013838	ENSPSIP00000019191	Ankyrin repeat domain 27.	RAB17, member RAS oncogene family.	0.597
ANKRD27	RAB20	ENSPSIP00000013838	ENSPSIP00000017255	Ankyrin repeat domain 27.	RAB20, member RAS oncogene family.	0.597
ANKRD27	RAB5A	ENSPSIP00000013838	ENSPSIP00000007889	Ankyrin repeat domain 27.	RAB5A, member RAS oncogene family.	0.597
ANKRD27	RAB5B	ENSPSIP00000013838	ENSPSIP00000003195	Ankyrin repeat domain 27.	RAB5B, member RAS oncogene family.	0.597
ANKRD27	RAB5C	ENSPSIP00000013838	ENSPSIP00000016824	Ankyrin repeat domain 27.	Uncharacterized protein.	0.597
ANKRD27	RABEP1	ENSPSIP00000013838	ENSPSIP00000008066	Ankyrin repeat domain 27.	Rabaptin, RAB GTPase binding effector protein 1.	0.780
ANKRD27	RABEP2	ENSPSIP00000013838	ENSPSIP00000002923	Ankyrin repeat domain 27.	Rabaptin, RAB GTPase binding effector protein 2.	0.780
ANKRD27	VAMP7	ENSPSIP00000013838	ENSPSIP00000013123	Ankyrin repeat domain 27.	Vesicle associated membrane protein 7; Belongs to the synaptobrevin family.	0.921
CCZ1	EEA1	ENSPSIP00000015925	ENSPSIP00000020546	Uncharacterized protein.	Early endosome antigen 1.	0.501
CCZ1	K7FQH3_PELSI	ENSPSIP00000015925	ENSPSIP00000010283	Uncharacterized protein.	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	0.970
CCZ1	K7G3G9_PELSI	ENSPSIP00000015925	ENSPSIP00000014830	Uncharacterized protein.	Uncharacterized protein.	0.965
CCZ1	K7GFP1_PELSI	ENSPSIP00000015925	ENSPSIP00000019102	Uncharacterized protein.	Uncharacterized protein.	0.532
CCZ1	LOC102444442	ENSPSIP00000015925	ENSPSIP00000014009	Uncharacterized protein.	Uncharacterized protein.	0.915
CCZ1	MON1B	ENSPSIP00000015925	ENSPSIP00000010454	Uncharacterized protein.	MON1 homolog B, secretory trafficking associated.	0.999
CCZ1	RAB17	ENSPSIP00000015925	ENSPSIP00000019191	Uncharacterized protein.	RAB17, member RAS oncogene family.	0.421
CCZ1	RAB5A	ENSPSIP00000015925	ENSPSIP00000007889	Uncharacterized protein.	RAB5A, member RAS oncogene family.	0.421
CCZ1	RAB5B	ENSPSIP00000015925	ENSPSIP00000003195	Uncharacterized protein.	RAB5B, member RAS oncogene family.	0.421
CCZ1	RAB5C	ENSPSIP00000015925	ENSPSIP00000016824	Uncharacterized protein.	Uncharacterized protein.	0.421