(5 nodes) Mixed, incl. CBF1-interacting co-repressor CIR, N-terminal domain, and Polo kinase kinase network (Pelodiscus sinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NRDE2	NRDE-2, necessary for RNA interference, domain containing. (1170 aa)
	CCDC174	Coiled-coil domain containing 174. (327 aa)
	STK10	Serine/threonine kinase 10. (733 aa)
	CIR1	Corepressor interacting with RBPJ, 1. (435 aa)
	FRG1	Uncharacterized protein. (261 aa)

Your Current Organism:

Pelodiscus sinensis

NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC174	NRDE2	ENSPSIP00000009903	ENSPSIP00000006020	Coiled-coil domain containing 174.	NRDE-2, necessary for RNA interference, domain containing.	0.689
CIR1	FRG1	ENSPSIP00000019823	ENSPSIP00000020291	Corepressor interacting with RBPJ, 1.	Uncharacterized protein.	0.601
CIR1	NRDE2	ENSPSIP00000019823	ENSPSIP00000006020	Corepressor interacting with RBPJ, 1.	NRDE-2, necessary for RNA interference, domain containing.	0.565
FRG1	CIR1	ENSPSIP00000020291	ENSPSIP00000019823	Uncharacterized protein.	Corepressor interacting with RBPJ, 1.	0.601
NRDE2	CCDC174	ENSPSIP00000006020	ENSPSIP00000009903	NRDE-2, necessary for RNA interference, domain containing.	Coiled-coil domain containing 174.	0.689
NRDE2	CIR1	ENSPSIP00000006020	ENSPSIP00000019823	NRDE-2, necessary for RNA interference, domain containing.	Corepressor interacting with RBPJ, 1.	0.565