STRINGSTRING
C16orf70 C16orf70 ATG12 ATG12 ULK3 ULK3 BCAS3 BCAS3 ULK2 ULK2 RB1CC1 RB1CC1 LOC102450218 LOC102450218 ATG16L2 ATG16L2 ATG7 ATG7 ATG2B ATG2B WDR45B WDR45B PIK3C3 PIK3C3 SNX30 SNX30 ATG14 ATG14 WIPI2 WIPI2 WIPI1 WIPI1 SQSTM1 SQSTM1 ATG2A ATG2A ULK1 ULK1 VMP1 VMP1 SNX7 SNX7 ATG13 ATG13 ZFYVE1 ZFYVE1 NBR1 NBR1 TRAPPC8 TRAPPC8 ILRUN ILRUN BECN1 BECN1 ATG5 ATG5 ATG101 ATG101 ATG16L1 ATG16L1 STBD1 STBD1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
C16orf70Chromosome 16 open reading frame 70. (423 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (143 aa)
ULK3Unc-51 like kinase 3. (439 aa)
BCAS3BCAS3 microtubule associated cell migration factor. (810 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1015 aa)
RB1CC1RB1 inducible coiled-coil 1. (1591 aa)
LOC102450218Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (273 aa)
ATG16L2Autophagy related 16 like 2. (449 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (661 aa)
ATG2BAutophagy related 2B. (2079 aa)
WDR45BWD repeat domain 45B. (335 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (864 aa)
SNX30Sorting nexin family member 30. (468 aa)
ATG14Autophagy related 14. (393 aa)
WIPI2WD repeat domain, phosphoinositide interacting 2. (414 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (422 aa)
SQSTM1Sequestosome 1. (437 aa)
ATG2AAutophagy related 2A. (2002 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1030 aa)
VMP1Vacuole membrane protein 1. (406 aa)
SNX7Sorting nexin 7. (442 aa)
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (555 aa)
ZFYVE1Zinc finger FYVE-type containing 1. (781 aa)
NBR1NBR1 autophagy cargo receptor. (995 aa)
TRAPPC8Trafficking protein particle complex 8. (1419 aa)
ILRUNInflammation and lipid regulator with UBA-like and NBR1-like domains. (217 aa)
BECN1Uncharacterized protein. (407 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (276 aa)
ATG101Autophagy related 101. (230 aa)
ATG16L1Autophagy related 16 like 1. (607 aa)
STBD1Starch binding domain 1. (200 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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