STRINGSTRING
FUNDC1 FUNDC1 PIN1 PIN1 FABP1 FABP1 TP53 TP53 MYOCD MYOCD P2RX3 P2RX3 LOC102446096 LOC102446096 K7G255_PELSI K7G255_PELSI EPAS1 EPAS1 TERT TERT NOL3 NOL3 SCAP SCAP TH TH LOC102453596 LOC102453596 MGARP MGARP TIGAR TIGAR OPRD1 OPRD1 VEGFC VEGFC TXN2 TXN2 VEGFB VEGFB SCFD1 SCFD1 HMOX2 HMOX2 PINK1 PINK1 EGLN1 EGLN1 STOX1 STOX1 EP300 EP300 DPP4 DPP4 PAM PAM NDRG1 NDRG1 LOC102458614 LOC102458614 KCNK2 KCNK2 NGB NGB EDN1 EDN1 SLC9A1 SLC9A1 TM9SF4 TM9SF4 BCL2 BCL2 HYOU1 HYOU1 NFE2L2 NFE2L2 REST REST CYGB CYGB SIRT2 SIRT2 MECP2 MECP2 LONP1 LONP1 ANG ANG K7FQ62_PELSI K7FQ62_PELSI CPEB2 CPEB2 GATA6 GATA6 NPEPPS NPEPPS SUV39H1 SUV39H1 ARNT ARNT TGFB2 TGFB2 MYC MYC WDR83 WDR83 USF1 USF1 HIF1AN HIF1AN VHL VHL FNDC1 FNDC1 MTOR MTOR CAV3 CAV3 PDK3 PDK3 K7FP83_PELSI K7FP83_PELSI NARF NARF HMOX1 HMOX1 PTGS2 PTGS2 K7FRV9_PELSI K7FRV9_PELSI HSP90B1 HSP90B1 ALKBH5 ALKBH5 AK4 AK4 P2RX2 P2RX2 EDNRA EDNRA SIRT1 SIRT1 VEGFD VEGFD PLAU PLAU PPARD PPARD AQP5 AQP5 PLAT PLAT SMAD4 SMAD4 TGFB3 TGFB3 DDIT4 DDIT4 LOXL2 LOXL2 PGF PGF NF1 NF1 NKX3-1 NKX3-1 EGLN3 EGLN3 FAM162A FAM162A MDM4 MDM4 LIMD1 LIMD1 RBPJ RBPJ CPEB1 CPEB1 BACH1 BACH1 SUV39H2 SUV39H2 BNIP3 BNIP3 HIF3A HIF3A DDR2 DDR2 TBL2 TBL2 WTIP WTIP ARNT2 ARNT2 LOC102454210 LOC102454210 AQP1 AQP1 HIF1A HIF1A NDNF NDNF VEGFA VEGFA ADAM17 ADAM17 CIAO3 CIAO3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FUNDC1FUN14 domain containing 1. (100 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (141 aa)
FABP1Fatty acid binding protein 1. (128 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (390 aa)
MYOCDPhosphatase and actin regulator. (916 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (396 aa)
LOC102446096BH4_AAA_HYDROXYL_2 domain-containing protein. (453 aa)
K7G255_PELSIPH domain-containing protein. (371 aa)
EPAS1Endothelial PAS domain protein 1. (872 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1256 aa)
NOL3CARD domain-containing protein. (230 aa)
SCAPSREBF chaperone. (1284 aa)
THTyrosine hydroxylase. (499 aa)
LOC102453596GLOBIN domain-containing protein; Belongs to the globin family. (148 aa)
MGARPAIF-MLS domain-containing protein. (60 aa)
TIGARUncharacterized protein. (274 aa)
OPRD1Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (290 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (367 aa)
TXN2Thioredoxin 2. (199 aa)
VEGFBPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (191 aa)
SCFD1Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family. (617 aa)
HMOX2Heme oxygenase 2. (315 aa)
PINK1PTEN induced kinase 1. (364 aa)
EGLN1Fe2OG dioxygenase domain-containing protein. (206 aa)
STOX1Storkhead box 1. (875 aa)
EP300E1A binding protein p300. (2399 aa)
DPP4Uncharacterized protein; Belongs to the peptidase S9B family. (760 aa)
PAMPeptidylglycine alpha-amidating monooxygenase. (973 aa)
NDRG1N-myc downstream regulated 1. (402 aa)
LOC102458614Uncharacterized protein. (824 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (410 aa)
NGBNeuroglobin; Belongs to the globin family. (160 aa)
EDN1Endothelin 1. (204 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (773 aa)
TM9SF4Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (642 aa)
BCL2BCL2 apoptosis regulator. (232 aa)
HYOU1Uncharacterized protein. (1000 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (573 aa)
RESTRE1 silencing transcription factor. (889 aa)
CYGBCytoglobin; Belongs to the globin family. (192 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (372 aa)
MECP2Methyl-CpG binding protein 2. (201 aa)
LONP1Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. ECO:0000256|PROSITE-. (819 aa)
ANGAngiogenin; Belongs to the pancreatic ribonuclease family. (161 aa)
K7FQ62_PELSIUncharacterized protein. (809 aa)
CPEB2Cytoplasmic polyadenylation element binding protein 2. (525 aa)
GATA6GATA binding protein 6. (514 aa)
NPEPPSAminopeptidase. (850 aa)
SUV39H1Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (397 aa)
ARNTAryl hydrocarbon receptor nuclear translocator. (793 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
MYCMYC proto-oncogene, bHLH transcription factor. (324 aa)
WDR83WD repeat domain 83. (317 aa)
USF1Upstream transcription factor 1. (331 aa)
HIF1ANHypoxia inducible factor 1 subunit alpha inhibitor. (296 aa)
VHLUncharacterized protein. (169 aa)
FNDC1Fibronectin type III domain containing 1. (1969 aa)
MTORSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2522 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
PDK3Protein-serine/threonine kinase. (413 aa)
K7FP83_PELSIBRCT domain-containing protein. (519 aa)
NARFNuclear prelamin A recognition factor; Belongs to the NARF family. (459 aa)
HMOX1Heme oxygenase 1. (335 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (658 aa)
K7FRV9_PELSIUncharacterized protein. (502 aa)
HSP90B1Heat shock protein 90 beta family member 1. (792 aa)
ALKBH5AlkB homolog 5, RNA demethylase. (386 aa)
AK4Adenylate kinase 4. (136 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (365 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (421 aa)
SIRT1Deacetylase sirtuin-type domain-containing protein. (607 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (353 aa)
PLAUUncharacterized protein. (440 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
AQP5Aquaporin 5; Belongs to the MIP/aquaporin (TC 1.A.8) family. (265 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (554 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
TGFB3Transforming growth factor beta 3. (456 aa)
DDIT4DNA damage inducible transcript 4. (223 aa)
LOXL2Lysyl oxidase like 2. (769 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (171 aa)
NF1Neurofibromin 1. (2788 aa)
NKX3-1NK3 homeobox 1. (212 aa)
EGLN3Egl-9 family hypoxia inducible factor 3. (241 aa)
FAM162AFamily with sequence similarity 162 member A. (153 aa)
MDM4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (473 aa)
LIMD1LIM domains containing 1. (608 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (465 aa)
CPEB1Uncharacterized protein. (335 aa)
BACH1BZIP domain-containing protein. (607 aa)
SUV39H2Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (410 aa)
BNIP3BCL2 interacting protein 3. (205 aa)
HIF3AHypoxia inducible factor 3 subunit alpha. (660 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (887 aa)
TBL2Transducin beta like 2. (409 aa)
WTIPWT1 interacting protein. (193 aa)
ARNT2Aryl hydrocarbon receptor nuclear translocator 2. (725 aa)
LOC102454210Uncharacterized protein. (487 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (811 aa)
NDNFNeuron derived neurotrophic factor. (568 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (217 aa)
ADAM17ADAM metallopeptidase domain 17. (836 aa)
CIAO3Cytosolic iron-sulfur assembly component 3; Belongs to the NARF family. (473 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
Server load: low (40%) [HD]