STRINGSTRING
LOC102449068 LOC102449068 K7FFJ3_PELSI K7FFJ3_PELSI OXSM OXSM K7FGN5_PELSI K7FGN5_PELSI LOC102449310 LOC102449310 FADS2 FADS2 K7FJI5_PELSI K7FJI5_PELSI K7FJP2_PELSI K7FJP2_PELSI ELOVL1 ELOVL1 ACSBG1 ACSBG1 ALOXE3 ALOXE3 ABCD3 ABCD3 LIAS LIAS LOC102459125 LOC102459125 ABHD3 ABHD3 PLA2G4A PLA2G4A HPGDS HPGDS PTGS2 PTGS2 LPL LPL ASAH2 ASAH2 FASN FASN ELOVL4 ELOVL4 DECR2 DECR2 HSDL1 HSDL1 DEGS1 DEGS1 ACLY ACLY MECR MECR ACACA ACACA PRKAG2 PRKAG2 HSD17B12 HSD17B12 K7FY56_PELSI K7FY56_PELSI DAGLB DAGLB QKI QKI K7G0M4_PELSI K7G0M4_PELSI K7G0U7_PELSI K7G0U7_PELSI HACD3 HACD3 LOC102445968 LOC102445968 ELOVL5 ELOVL5 MGLL MGLL PRKAB2 PRKAB2 THNSL2 THNSL2 ACSM5 ACSM5 SCD SCD ACSF3 ACSF3 MCAT MCAT ALOX5 ALOX5 K7G437_PELSI K7G437_PELSI PRKAA1 PRKAA1 CD74 CD74 ABHD2 ABHD2 NDUFAB1 NDUFAB1 ELOVL7 ELOVL7 LIPC LIPC PLA2G10 PLA2G10 PECR PECR TBXAS1 TBXAS1 K7G9Q4_PELSI K7G9Q4_PELSI GSTP1 GSTP1 MLYCD MLYCD SCD5 SCD5 ELOVL3 ELOVL3 HACD1 HACD1 PRKAB1 PRKAB1 CBR4 CBR4 LIPI LIPI PTGES2 PTGES2 TECR TECR SUGCT SUGCT PNPLA8 PNPLA8 LIPH LIPH HACD4 HACD4 ARMC7 ARMC7 K7FEB4_PELSI K7FEB4_PELSI PALB2 PALB2 LOC102450917 LOC102450917 ACOT7 ACOT7 PTGES PTGES K7FC61_PELSI K7FC61_PELSI HACD2 HACD2 HTD2 HTD2 ACACB ACACB K7FB16_PELSI K7FB16_PELSI PTGS1 PTGS1 ELOVL2 ELOVL2 EDN1 EDN1 TMEM196 TMEM196 PRXL2B PRXL2B PLP1 PLP1 LOC102456931 LOC102456931 PRKAA2 PRKAA2 PTGES3 PTGES3 TECRL TECRL ELOVL6 ELOVL6 LOC102450450 LOC102450450 ACSBG2 ACSBG2 THNSL1 THNSL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102449068Phospholipase A2. (660 aa)
K7FFJ3_PELSIUncharacterized protein. (182 aa)
OXSM3-oxoacyl-[acyl-carrier-protein] synthase; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (459 aa)
K7FGN5_PELSIUncharacterized protein. (189 aa)
LOC102449310Phospholipase A2. (850 aa)
FADS2Cytochrome b5 heme-binding domain-containing protein. (444 aa)
K7FJI5_PELSIElongation of very long chain fatty acids protein. (100 aa)
K7FJP2_PELSIElongation of very long chain fatty acids protein. (280 aa)
ELOVL1Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (287 aa)
ACSBG1Acyl-CoA synthetase bubblegum family member 1. (681 aa)
ALOXE3Arachidonate lipoxygenase 3. (671 aa)
ABCD3ATP binding cassette subfamily D member 3. (648 aa)
LIASLipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (358 aa)
LOC102459125S5A_REDUCTASE domain-containing protein. (308 aa)
ABHD3Abhydrolase domain containing 3. (411 aa)
PLA2G4APhospholipase A2. (749 aa)
HPGDSHematopoietic prostaglandin D synthase; Belongs to the GST superfamily. (199 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (658 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (469 aa)
ASAH2Neutral ceramidase. (730 aa)
FASNFatty acid synthase. (2015 aa)
ELOVL4Elongation of very long chain fatty acids protein. (272 aa)
DECR22,4-dienoyl-CoA reductase 2. (266 aa)
HSDL1Hydroxysteroid dehydrogenase like 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (332 aa)
DEGS1Delta 4-desaturase, sphingolipid 1. (323 aa)
ACLYATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1091 aa)
MECRMitochondrial trans-2-enoyl-CoA reductase. (299 aa)
ACACAAcetyl-CoA carboxylase alpha. (2347 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (564 aa)
HSD17B12Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (238 aa)
K7FY56_PELSIUncharacterized protein. (164 aa)
DAGLBDiacylglycerol lipase beta. (713 aa)
QKIQKI, KH domain containing RNA binding. (340 aa)
K7G0M4_PELSIUncharacterized protein. (580 aa)
K7G0U7_PELSIAMP-binding domain-containing protein. (440 aa)
HACD3Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (347 aa)
LOC102445968Uncharacterized protein. (583 aa)
ELOVL5Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (297 aa)
MGLLMonoglyceride lipase. (311 aa)
PRKAB2Protein kinase AMP-activated non-catalytic subunit beta 2. (274 aa)
THNSL2Threonine synthase like 2. (477 aa)
ACSM5Acyl-CoA synthetase medium chain family member 5. (580 aa)
SCDStearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (326 aa)
ACSF3Acyl-CoA synthetase family member 3. (533 aa)
MCATMalonyl-CoA-acyl carrier protein transacylase. (211 aa)
ALOX5Arachidonate 5-lipoxygenase. (623 aa)
K7G437_PELSICytochrome b5 heme-binding domain-containing protein. (423 aa)
PRKAA1Non-specific serine/threonine protein kinase. (560 aa)
CD74CD74 molecule. (293 aa)
ABHD2Abhydrolase domain containing 2. (427 aa)
NDUFAB1Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (148 aa)
ELOVL7Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (283 aa)
LIPCLipase C, hepatic type. (498 aa)
PLA2G10Phospholipase A(2). (143 aa)
PECRPeroxisomal trans-2-enoyl-CoA reductase. (158 aa)
TBXAS1Uncharacterized protein; Belongs to the cytochrome P450 family. (297 aa)
K7G9Q4_PELSIUncharacterized protein. (174 aa)
GSTP1Glutathione S-transferase pi 1; Belongs to the GST superfamily. (212 aa)
MLYCDMalonyl-CoA decarboxylase. (316 aa)
SCD5Stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (278 aa)
ELOVL3Elongation of very long chain fatty acids protein. (176 aa)
HACD1Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (204 aa)
PRKAB1Protein kinase AMP-activated non-catalytic subunit beta 1. (263 aa)
CBR4Carbonyl reductase 4; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (228 aa)
LIPILipase domain-containing protein. (457 aa)
PTGES2Prostaglandin E synthase 2; Belongs to the GST superfamily. (382 aa)
TECRTrans-2,3-enoyl-CoA reductase. (329 aa)
SUGCTSuccinyl-CoA:glutarate-CoA transferase. (400 aa)
PNPLA8Patatin like phospholipase domain containing 8. (804 aa)
LIPHLipase H. (450 aa)
HACD4Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (219 aa)
ARMC7Uncharacterized protein. (190 aa)
K7FEB4_PELSIFA_desaturase domain-containing protein. (322 aa)
PALB2Partner and localizer of BRCA2. (1111 aa)
LOC102450917Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (190 aa)
ACOT7Acyl-CoA thioesterase 7. (363 aa)
PTGESProstaglandin E synthase. (152 aa)
K7FC61_PELSIBRCT_assoc domain-containing protein. (1048 aa)
HACD2Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (143 aa)
HTD2Hydroxyacyl-thioester dehydratase type 2. (169 aa)
ACACBAcetyl-CoA carboxylase beta. (2445 aa)
K7FB16_PELSIUncharacterized protein. (1346 aa)
PTGS1Prostaglandin-endoperoxide synthase 1. (576 aa)
ELOVL2Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] (280 aa)
EDN1Endothelin 1. (204 aa)
TMEM196Transmembrane protein 196. (178 aa)
PRXL2BUncharacterized protein. (201 aa)
PLP1Proteolipid protein 1. (242 aa)
LOC102456931Uncharacterized protein. (145 aa)
PRKAA2Non-specific serine/threonine protein kinase. (520 aa)
PTGES3Prostaglandin E synthase 3. (154 aa)
TECRLTrans-2,3-enoyl-CoA reductase like. (372 aa)
ELOVL6Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (266 aa)
LOC102450450Phospholipase A(2). (156 aa)
ACSBG2Acyl-CoA synthetase bubblegum family member 2. (715 aa)
THNSL1Threonine synthase like 1. (737 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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