7 items (Pelodiscus sinensis) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	ATG7	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (661 aa)
	MAP1LC3B	Uncharacterized protein. (112 aa)
	BECN1	Uncharacterized protein. (407 aa)
	GABARAPL2	GABA type A receptor associated protein like 2. (106 aa)
	MAP1LC3A	Microtubule associated protein 1 light chain 3 alpha. (121 aa)
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (276 aa)
	MAP1LC3C	Microtubule associated protein 1 light chain 3 gamma. (143 aa)

Your Current Organism:

Pelodiscus sinensis

NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG5	ATG7	ENSPSIP00000002735	ENSPSIP00000013932	Autophagy protein 5; Involved in autophagic vesicle formation.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.994
ATG5	BECN1	ENSPSIP00000002735	ENSPSIP00000004890	Autophagy protein 5; Involved in autophagic vesicle formation.	Uncharacterized protein.	0.892
ATG5	GABARAPL2	ENSPSIP00000002735	ENSPSIP00000011948	Autophagy protein 5; Involved in autophagic vesicle formation.	GABA type A receptor associated protein like 2.	0.895
ATG5	MAP1LC3A	ENSPSIP00000002735	ENSPSIP00000012366	Autophagy protein 5; Involved in autophagic vesicle formation.	Microtubule associated protein 1 light chain 3 alpha.	0.808
ATG5	MAP1LC3B	ENSPSIP00000002735	ENSPSIP00000019097	Autophagy protein 5; Involved in autophagic vesicle formation.	Uncharacterized protein.	0.808
ATG5	MAP1LC3C	ENSPSIP00000002735	ENSPSIP00000014156	Autophagy protein 5; Involved in autophagic vesicle formation.	Microtubule associated protein 1 light chain 3 gamma.	0.736
ATG7	ATG5	ENSPSIP00000013932	ENSPSIP00000002735	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Autophagy protein 5; Involved in autophagic vesicle formation.	0.994
ATG7	BECN1	ENSPSIP00000013932	ENSPSIP00000004890	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Uncharacterized protein.	0.825
ATG7	GABARAPL2	ENSPSIP00000013932	ENSPSIP00000011948	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	GABA type A receptor associated protein like 2.	0.976
ATG7	MAP1LC3A	ENSPSIP00000013932	ENSPSIP00000012366	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Microtubule associated protein 1 light chain 3 alpha.	0.908
ATG7	MAP1LC3B	ENSPSIP00000013932	ENSPSIP00000019097	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Uncharacterized protein.	0.908
ATG7	MAP1LC3C	ENSPSIP00000013932	ENSPSIP00000014156	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	Microtubule associated protein 1 light chain 3 gamma.	0.889
BECN1	ATG5	ENSPSIP00000004890	ENSPSIP00000002735	Uncharacterized protein.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.892
BECN1	ATG7	ENSPSIP00000004890	ENSPSIP00000013932	Uncharacterized protein.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.825
BECN1	GABARAPL2	ENSPSIP00000004890	ENSPSIP00000011948	Uncharacterized protein.	GABA type A receptor associated protein like 2.	0.810
BECN1	MAP1LC3A	ENSPSIP00000004890	ENSPSIP00000012366	Uncharacterized protein.	Microtubule associated protein 1 light chain 3 alpha.	0.810
BECN1	MAP1LC3B	ENSPSIP00000004890	ENSPSIP00000019097	Uncharacterized protein.	Uncharacterized protein.	0.702
BECN1	MAP1LC3C	ENSPSIP00000004890	ENSPSIP00000014156	Uncharacterized protein.	Microtubule associated protein 1 light chain 3 gamma.	0.804
GABARAPL2	ATG5	ENSPSIP00000011948	ENSPSIP00000002735	GABA type A receptor associated protein like 2.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.895
GABARAPL2	ATG7	ENSPSIP00000011948	ENSPSIP00000013932	GABA type A receptor associated protein like 2.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.976