STRINGSTRING
FBN1 FBN1 ZDHHC16 ZDHHC16 MAP2K4 MAP2K4 PDGFRB PDGFRB STK4 STK4 PDLIM3 PDLIM3 GATA3 GATA3 WNT11 WNT11 BMPR2 BMPR2 WT1 WT1 NODAL NODAL SMYD1 SMYD1 CCN1 CCN1 MKS1 MKS1 DLL4 DLL4 SLIT2 SLIT2 MNAT1 MNAT1 MYL10 MYL10 GREB1 GREB1 IFT20 IFT20 PTCD2 PTCD2 DYNC2H1 DYNC2H1 MATR3 MATR3 TNNC1 TNNC1 LOC102449308 LOC102449308 LOC102449702 LOC102449702 SMAD4 SMAD4 TRIP11 TRIP11 PRICKLE1 PRICKLE1 BCOR BCOR NKX2-5 NKX2-5 MEF2A MEF2A CACYBP CACYBP AKAP13 AKAP13 RB1CC1 RB1CC1 GCC1 GCC1 LRRC10B LRRC10B MTERF4 MTERF4 SMYD4 SMYD4 VWA5B2 VWA5B2 ALCAM ALCAM TBX19 TBX19 GJC1 GJC1 DRC1 DRC1 ECE2 ECE2 ADRA1A ADRA1A ID3 ID3 FRS2 FRS2 DIPK2A DIPK2A TBX20 TBX20 TAB2 TAB2 FN1 FN1 IFT52 IFT52 IFT57 IFT57 MIXL1 MIXL1 SNAI2 SNAI2 CPLANE1 CPLANE1 SMAD1 SMAD1 AP1B1 AP1B1 WNT2 WNT2 MSX1 MSX1 LOC102461145 LOC102461145 CASP7 CASP7 SGCB SGCB NEB NEB NPY5R NPY5R TSC2 TSC2 MYOCD MYOCD TP53 TP53 ATG5 ATG5 PRDM1 PRDM1 BVES BVES CCDC40 CCDC40 KCNJ8 KCNJ8 CTNNB1 CTNNB1 SETDB2 SETDB2 LRRC10 LRRC10 FOXC2 FOXC2 FLRT3 FLRT3 LOC102446096 LOC102446096 ARL13B ARL13B TGFBR1 TGFBR1 SEMA3C SEMA3C K7GJ94_PELSI K7GJ94_PELSI K7GJ89_PELSI K7GJ89_PELSI TBX6 TBX6 GLI3 GLI3 ACVRL1 ACVRL1 K7GIA0_PELSI K7GIA0_PELSI ALPK3 ALPK3 K7GHY0_PELSI K7GHY0_PELSI NOX4 NOX4 TBX2 TBX2 GREM1 GREM1 NF1 NF1 GALNT11 GALNT11 NKX3-1 NKX3-1 SETD2 SETD2 CXADR CXADR NRAP NRAP ANKS6 ANKS6 MDM4 MDM4 SLIT3 SLIT3 CLUAP1 CLUAP1 NCOA6 NCOA6 BMP4 BMP4 BMP5 BMP5 SOS1 SOS1 HAND2 HAND2 SFRP2 SFRP2 ANKRD1 ANKRD1 K7G1E4_PELSI K7G1E4_PELSI TMED2 TMED2 NIPBL NIPBL MEF2C MEF2C BMP7 BMP7 LOC102460008 LOC102460008 NPRL3 NPRL3 TEK TEK TH TH LOC102449564 LOC102449564 PDGFB PDGFB LOC106732081 LOC106732081 MAP2K5 MAP2K5 PLN PLN K7FYF9_PELSI K7FYF9_PELSI SYPL2 SYPL2 HSPB7 HSPB7 K7FXZ1_PELSI K7FXZ1_PELSI CER1 CER1 LOC102456320 LOC102456320 STRA6 STRA6 TAB1 TAB1 GJA5 GJA5 VEGFB VEGFB NOTCH1 NOTCH1 AHI1 AHI1 SMAD3 SMAD3 DNAI1 DNAI1 LOX LOX PPP3R1 PPP3R1 PNO1 PNO1 TIE1 TIE1 STIL STIL ENG ENG MEF2D MEF2D MICAL2 MICAL2 TSC1 TSC1 TTC25 TTC25 RBM20 RBM20 K7FSR3_PELSI K7FSR3_PELSI BICC1 BICC1 DLL1 DLL1 ALPK2 ALPK2 IFT74 IFT74 KDR KDR SOX18 SOX18 ACVR1 ACVR1 FOXL1 FOXL1 TNFRSF1B TNFRSF1B ACADM ACADM K7FR22_PELSI K7FR22_PELSI SOX17 SOX17 FGF19 FGF19 PSKH1 PSKH1 RB1 RB1 CCDC151 CCDC151 GSK3B GSK3B SALL4 SALL4 GATA6 GATA6 TMEM65 TMEM65 MIB1 MIB1 ASB2 ASB2 KCNQ1 KCNQ1 GREB1L GREB1L SIRT6 SIRT6 JAG1 JAG1 PTCH1 PTCH1 TGFB2 TGFB2 SMG9 SMG9 CALCRL CALCRL FGF8 FGF8 PLXND1 PLXND1 CSRP3 CSRP3 K7FLF5_PELSI K7FLF5_PELSI ECE1 ECE1 SGCG SGCG ILK ILK AP2B1 AP2B1 POPDC2 POPDC2 WDR11 WDR11 RPGRIP1L RPGRIP1L IFT140 IFT140 TFDP2 TFDP2 K7FJB8_PELSI K7FJB8_PELSI TNNI1 TNNI1 JARID2 JARID2 MTOR MTOR PKD1 PKD1 PDLIM5 PDLIM5 WNT16 WNT16 MED1 MED1 IRX3 IRX3 SMO SMO ARID2 ARID2 SMAD2 SMAD2 NSD2 NSD2 BBS7 BBS7 K7FGV8_PELSI K7FGV8_PELSI BORCS8 BORCS8 SPRED1 SPRED1 PSEN1 PSEN1 EDNRA EDNRA K7FFP6_PELSI K7FFP6_PELSI ATM ATM SMAD7 SMAD7 MAML1 MAML1 PDLIM4 PDLIM4 PKP2 PKP2 DHRS3 DHRS3 CCM2 CCM2 DCTN5 DCTN5 HECTD1 HECTD1 TBXT TBXT BMP2 BMP2 NRP2 NRP2 ZBTB14 ZBTB14 PDLIM1 PDLIM1 EOMES EOMES FREM2 FREM2 TGFBR2 TGFBR2 IFT172 IFT172 SAV1 SAV1 CPE CPE PKD2 PKD2 HTR2B HTR2B TMEM100 TMEM100 CITED2 CITED2 JUN JUN NPY2R NPY2R APLNR APLNR K7F2Q9_PELSI K7F2Q9_PELSI NEK8 NEK8 EP300 EP300 ARMC4 ARMC4 PAM PAM LOC102446095 LOC102446095 K7FA56_PELSI K7FA56_PELSI K7F9Y9_PELSI K7F9Y9_PELSI KCNK2 KCNK2 ZFPM2 ZFPM2 EDN1 EDN1 CCDC103 CCDC103 GATA5 GATA5 RAMP2 RAMP2 CBY1 CBY1 GJA1 GJA1 TBC1D32 TBC1D32 CNTRL CNTRL POFUT1 POFUT1 SGCD SGCD SLC9A1 SLC9A1 TRAF3IP2 TRAF3IP2 SUFU SUFU TENM4 TENM4 WNT2B WNT2B SNAI1 SNAI1 CCM2L CCM2L LOC102457599 LOC102457599 MYL2 MYL2 DNAAF1 DNAAF1 GATA4 GATA4 HOPX HOPX K7F5B5_PELSI K7F5B5_PELSI RPS6KA2 RPS6KA2 LUZP1 LUZP1 REST REST HSPB11 HSPB11 JMJD6 JMJD6 FLRT2 FLRT2 HOXA13 HOXA13
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FBN1Fibrillin 1. (2872 aa)
ZDHHC16Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (144 aa)
MAP2K4Mitogen-activated protein kinase kinase 4. (328 aa)
PDGFRBPlatelet derived growth factor receptor beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1068 aa)
STK4Serine/threonine kinase 4. (486 aa)
PDLIM3PDZ and LIM domain 3. (366 aa)
GATA3GATA binding protein 3. (425 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1042 aa)
WT1WT1 transcription factor. (415 aa)
NODALTGF_BETA_2 domain-containing protein. (418 aa)
SMYD1SET and MYND domain containing 1. (491 aa)
CCN1Cellular communication network factor 1. (375 aa)
MKS1MKS transition zone complex subunit 1. (402 aa)
DLL4Delta like canonical Notch ligand 4. (684 aa)
SLIT2Slit guidance ligand 2. (1381 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
MYL10Uncharacterized protein. (166 aa)
GREB1Uncharacterized protein. (1604 aa)
IFT20Intraflagellar transport 20. (132 aa)
PTCD2Pentatricopeptide repeat domain 2. (323 aa)
DYNC2H1Dynein cytoplasmic 2 heavy chain 1. (4313 aa)
MATR3Uncharacterized protein. (905 aa)
TNNC1Troponin C1, slow skeletal and cardiac type. (161 aa)
LOC102449308EGF-like domain-containing protein. (187 aa)
LOC102449702EGF-like domain-containing protein. (203 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
TRIP11GRIP domain-containing protein. (666 aa)
PRICKLE1Prickle planar cell polarity protein 1. (830 aa)
BCORBCL6 corepressor. (1762 aa)
NKX2-5NK2 homeobox 5. (272 aa)
MEF2AMyocyte enhancer factor 2A. (481 aa)
CACYBPCalcyclin binding protein. (217 aa)
AKAP13A-kinase anchoring protein 13. (2319 aa)
RB1CC1RB1 inducible coiled-coil 1. (1591 aa)
GCC1GRIP and coiled-coil domain containing 1. (748 aa)
LRRC10BLeucine rich repeat containing 10B. (233 aa)
MTERF4Mitochondrial transcription termination factor 4. (382 aa)
SMYD4SET and MYND domain containing 4. (730 aa)
VWA5B2Von Willebrand factor A domain containing 5B2. (1274 aa)
ALCAMActivated leukocyte cell adhesion molecule. (541 aa)
TBX19T-box transcription factor 19. (429 aa)
GJC1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (393 aa)
DRC1Dynein regulatory complex subunit 1. (415 aa)
ECE2Uncharacterized protein. (770 aa)
ADRA1AAdrenoceptor alpha 1A. (467 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (125 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
DIPK2ADivergent protein kinase domain 2A. (297 aa)
TBX20T-box transcription factor 20. (441 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (692 aa)
FN1Fibronectin 1. (2389 aa)
IFT52Intraflagellar transport 52. (437 aa)
IFT57Intraflagellar transport 57. (360 aa)
MIXL1Homeobox domain-containing protein. (174 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
CPLANE1Uncharacterized protein. (2039 aa)
SMAD1Mothers against decapentaplegic homolog. (427 aa)
AP1B1AP complex subunit beta. (955 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
MSX1Msh homeobox 1. (299 aa)
LOC102461145Uncharacterized protein; Belongs to the vasopressin/oxytocin family. (124 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (312 aa)
SGCBSarcoglycan beta. (306 aa)
NEBNebulin. (6636 aa)
NPY5RNeuropeptide Y receptor Y5. (444 aa)
TSC2TSC complex subunit 2. (1816 aa)
MYOCDPhosphatase and actin regulator. (916 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (390 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (276 aa)
PRDM1PR/SET domain 1. (787 aa)
BVESBlood vessel epicardial substance. (616 aa)
CCDC40Coiled-coil domain containing 40. (861 aa)
KCNJ8Potassium voltage-gated channel subfamily J member 8. (421 aa)
CTNNB1Uncharacterized protein. (778 aa)
SETDB2SET domain bifurcated histone lysine methyltransferase 2. (766 aa)
LRRC10Uncharacterized protein. (270 aa)
FOXC2Forkhead box C2. (458 aa)
FLRT3Fibronectin leucine rich transmembrane protein 3. (649 aa)
LOC102446096BH4_AAA_HYDROXYL_2 domain-containing protein. (453 aa)
ARL13BADP ribosylation factor like GTPase 13B. (409 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (750 aa)
K7GJ94_PELSIPDZ domain-containing protein. (344 aa)
K7GJ89_PELSIUncharacterized protein. (487 aa)
TBX6T-box transcription factor 6. (286 aa)
GLI3GLI family zinc finger 3. (1575 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (479 aa)
K7GIA0_PELSIUncharacterized protein. (212 aa)
ALPK3Alpha kinase 3. (1553 aa)
K7GHY0_PELSILRRNT domain-containing protein. (72 aa)
NOX4NADPH oxidase 4. (459 aa)
TBX2T-box transcription factor 2. (381 aa)
GREM1Gremlin. (182 aa)
NF1Neurofibromin 1. (2788 aa)
GALNT11Polypeptide N-acetylgalactosaminyltransferase. (608 aa)
NKX3-1NK3 homeobox 1. (212 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2555 aa)
CXADRUncharacterized protein. (368 aa)
NRAPNebulin related anchoring protein. (1737 aa)
ANKS6Ankyrin repeat and sterile alpha motif domain containing 6. (874 aa)
MDM4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (473 aa)
SLIT3Slit guidance ligand 3. (1396 aa)
CLUAP1Clusterin associated protein 1. (432 aa)
NCOA6Nuclear receptor coactivator 6. (1042 aa)
BMP4Bone morphogenetic protein 4. (353 aa)
BMP5Bone morphogenetic protein 5. (439 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1304 aa)
HAND2Heart and neural crest derivatives expressed 2. (205 aa)
SFRP2Secreted frizzled related protein 2. (150 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
K7G1E4_PELSIGOLD domain-containing protein. (206 aa)
TMED2GOLD domain-containing protein. (156 aa)
NIPBLNipped-B protein. (2788 aa)
MEF2CMyocyte enhancer factor 2C. (478 aa)
BMP7Bone morphogenetic protein 7. (436 aa)
LOC102460008G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (346 aa)
NPRL3NPR3 like, GATOR1 complex subunit. (491 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
THTyrosine hydroxylase. (499 aa)
LOC102449564Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (388 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (245 aa)
LOC106732081Protein kinase domain-containing protein. (174 aa)
MAP2K5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (413 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
K7FYF9_PELSIIon_trans domain-containing protein; Belongs to the potassium channel family. (300 aa)
SYPL2Synaptophysin like 2. (215 aa)
HSPB7Heat shock protein family B (small) member 7; Belongs to the small heat shock protein (HSP20) family. (162 aa)
K7FXZ1_PELSIKCNQ_channel domain-containing protein. (99 aa)
CER1Cerberus 1, DAN family BMP antagonist. (275 aa)
LOC102456320Uncharacterized protein. (217 aa)
STRA6Stimulated by retinoic acid 6. (666 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (563 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (369 aa)
VEGFBPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (191 aa)
NOTCH1Notch receptor 1. (2494 aa)
AHI1Abelson helper integration site 1. (1251 aa)
SMAD3Mothers against decapentaplegic homolog. (358 aa)
DNAI1Dynein axonemal intermediate chain 1. (672 aa)
LOXLysyl oxidase. (226 aa)
PPP3R1Uncharacterized protein. (161 aa)
PNO1Partner of NOB1 homolog. (206 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (740 aa)
STILSTIL centriolar assembly protein. (1327 aa)
ENGEndoglin. (652 aa)
MEF2DMyocyte enhancer factor 2D. (533 aa)
MICAL2Microtubule associated monooxygenase, calponin and LIM domain containing 2. (1061 aa)
TSC1TSC complex subunit 1. (1168 aa)
TTC25Tetratricopeptide repeat domain 25. (467 aa)
RBM20RNA binding motif protein 20. (1194 aa)
K7FSR3_PELSIAlpha-type protein kinase domain-containing protein. (232 aa)
BICC1BicC family RNA binding protein 1. (896 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (726 aa)
ALPK2Ig-like domain-containing protein. (1478 aa)
IFT74Intraflagellar transport 74. (668 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1328 aa)
SOX18SRY-box transcription factor 18. (343 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (511 aa)
FOXL1Forkhead box L1. (347 aa)
TNFRSF1BTNF receptor superfamily member 1B. (476 aa)
ACADMAcyl-CoA dehydrogenase medium chain. (381 aa)
K7FR22_PELSIUncharacterized protein. (245 aa)
SOX17SRY-box transcription factor 17. (344 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa)
PSKH1Protein serine kinase H1; Belongs to the protein kinase superfamily. (418 aa)
RB1RB transcriptional corepressor 1. (917 aa)
CCDC151Coiled-coil domain containing 151. (413 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (419 aa)
SALL4Spalt like transcription factor 4. (1109 aa)
GATA6GATA binding protein 6. (514 aa)
TMEM65Transmembrane protein 65. (103 aa)
MIB1Mindbomb E3 ubiquitin protein ligase 1. (1006 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (652 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (374 aa)
GREB1LGREB1 like retinoic acid receptor coactivator. (1919 aa)
SIRT6Sirtuin 6. (341 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1184 aa)
PTCH1Patched 1. (1442 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
SMG9SMG9 nonsense mediated mRNA decay factor. (490 aa)
CALCRLCalcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (468 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
PLXND1Plexin D1. (1550 aa)
CSRP3Cysteine and glycine rich protein 3. (193 aa)
K7FLF5_PELSIUncharacterized protein. (348 aa)
ECE1Endothelin converting enzyme 1. (846 aa)
SGCGSarcoglycan gamma. (291 aa)
ILKIntegrin linked kinase. (311 aa)
AP2B1AP complex subunit beta. (937 aa)
POPDC2Popeye domain containing 2. (355 aa)
WDR11WD repeat domain 11. (1196 aa)
RPGRIP1LRPGRIP1 like. (1017 aa)
IFT140Intraflagellar transport 140. (1462 aa)
TFDP2Transcription factor. (446 aa)
K7FJB8_PELSIGOLD domain-containing protein. (96 aa)
TNNI1Troponin I1, slow skeletal type. (188 aa)
JARID2Jumonji and AT-rich interaction domain containing 2. (1232 aa)
MTORSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2522 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4156 aa)
PDLIM5PDZ and LIM domain 5. (603 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1574 aa)
IRX3Iroquois homeobox 3. (334 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (677 aa)
ARID2AT-rich interaction domain 2. (1824 aa)
SMAD2Mothers against decapentaplegic homolog. (496 aa)
NSD2Nuclear receptor binding SET domain protein 2. (1365 aa)
BBS7Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (716 aa)
K7FGV8_PELSIProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (336 aa)
BORCS8Uncharacterized protein. (108 aa)
SPRED1Sprouty related EVH1 domain containing 1. (213 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (421 aa)
K7FFP6_PELSITBX domain-containing protein. (563 aa)
ATMNon-specific serine/threonine protein kinase. (3061 aa)
SMAD7Mothers against decapentaplegic homolog. (387 aa)
MAML1Mastermind like transcriptional coactivator 1. (763 aa)
PDLIM4PDZ and LIM domain 4. (299 aa)
PKP2Plakophilin 2. (878 aa)
DHRS3Dehydrogenase/reductase 3. (302 aa)
CCM2CCM2 scaffold protein. (452 aa)
DCTN5Dynactin subunit 5. (145 aa)
HECTD1HECT domain E3 ubiquitin protein ligase 1. (2523 aa)
TBXTT-box transcription factor T. (435 aa)
BMP2Bone morphogenetic protein 2. (389 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (910 aa)
ZBTB14Zinc finger and BTB domain containing 14. (448 aa)
PDLIM1PDZ and LIM domain 1. (301 aa)
EOMESEomesodermin. (571 aa)
FREM2FRAS1 related extracellular matrix 2. (3151 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (584 aa)
IFT172Intraflagellar transport 172. (508 aa)
SAV1Salvador family WW domain containing protein 1. (313 aa)
CPECarboxypeptidase E. (475 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (809 aa)
HTR2B5-hydroxytryptamine receptor 2B. (433 aa)
TMEM100Transmembrane protein 100. (134 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (231 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (314 aa)
NPY2RNeuropeptide Y receptor Y2; Belongs to the G-protein coupled receptor 1 family. (373 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (374 aa)
K7F2Q9_PELSIEGF_CA domain-containing protein. (370 aa)
NEK8NIMA related kinase 8. (514 aa)
EP300E1A binding protein p300. (2399 aa)
ARMC4Armadillo repeat containing 4. (1055 aa)
PAMPeptidylglycine alpha-amidating monooxygenase. (973 aa)
LOC102446095Homeobox domain-containing protein. (224 aa)
K7FA56_PELSIUncharacterized protein. (4129 aa)
K7F9Y9_PELSIUncharacterized protein. (284 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (410 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1004 aa)
EDN1Endothelin 1. (204 aa)
CCDC103Coiled-coil domain containing 103. (241 aa)
GATA5GATA binding protein 5. (398 aa)
RAMP2Receptor activity modifying protein 2. (180 aa)
CBY1Chibby family member 1, beta catenin antagonist. (156 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (381 aa)
TBC1D32TBC1 domain family member 32. (1075 aa)
CNTRLCentriolin. (2366 aa)
POFUT1Protein O-fucosyltransferase 1. (329 aa)
SGCDSarcoglycan delta. (288 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (773 aa)
TRAF3IP2SEFIR domain-containing protein. (556 aa)
SUFUSUFU negative regulator of hedgehog signaling. (426 aa)
TENM4Teneurin transmembrane protein 4. (2608 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (334 aa)
SNAI1Snail family transcriptional repressor 1. (258 aa)
CCM2LCCM2 like scaffold protein. (553 aa)
LOC102457599TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
MYL2Myosin light chain 2. (196 aa)
DNAAF1Dynein assembly factor 1, axonemal. (708 aa)
GATA4GATA binding protein 4. (247 aa)
HOPXHOP homeobox. (73 aa)
K7F5B5_PELSIUncharacterized protein. (407 aa)
RPS6KA2Ribosomal protein S6 kinase. (734 aa)
LUZP1Leucine zipper protein 1. (1120 aa)
RESTRE1 silencing transcription factor. (889 aa)
HSPB11Heat shock protein family B (small) member 11. (153 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (374 aa)
FLRT2Fibronectin leucine rich transmembrane protein 2. (661 aa)
HOXA13Homeobox domain-containing protein. (305 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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