STRINGSTRING
FOXK2 FOXK2 FBXO7 FBXO7 TIGAR TIGAR TPCN1 TPCN1 SNX30 SNX30 SCFD1 SCFD1 TFEB TFEB KIAA0408 KIAA0408 K7FVY0_PELSI K7FVY0_PELSI ULK2 ULK2 BOK BOK SNX7 SNX7 FOXO3 FOXO3 GPR137B GPR137B GFAP GFAP MFSD8 MFSD8 ACER2 ACER2 ROCK1 ROCK1 SESN1 SESN1 MTMR4 MTMR4 PAFAH1B2 PAFAH1B2 BAG3 BAG3 WDR41 WDR41 K7GBN9_PELSI K7GBN9_PELSI DRAM1 DRAM1 K7G6G8_PELSI K7G6G8_PELSI SUPT5H SUPT5H LZTS1 LZTS1 DEPDC5 DEPDC5 HTT HTT XBP1 XBP1 RB1CC1 RB1CC1 C9orf72 C9orf72 FLCN FLCN FEZ2 FEZ2 BCL2L11 BCL2L11 K7FN03_PELSI K7FN03_PELSI K7FNI3_PELSI K7FNI3_PELSI FYCO1 FYCO1 ULK1 ULK1 GSK3B GSK3B LEPR LEPR RAB3GAP2 RAB3GAP2 MTMR9 MTMR9 CISD2 CISD2 MTOR MTOR SESN3 SESN3 ERCC4 ERCC4 SPTLC1 SPTLC1 NPRL2 NPRL2 K7FGV8_PELSI K7FGV8_PELSI K7FGU8_PELSI K7FGU8_PELSI K7FGU4_PELSI K7FGU4_PELSI AMBRA1 AMBRA1 ZC3H12A ZC3H12A SCOC SCOC PARL PARL FEZ1 FEZ1 TP53INP1 TP53INP1 ATG2A ATG2A KDR KDR BMF BMF RIPK2 RIPK2 WIPI1 WIPI1 FBXW9 FBXW9 RRAGD RRAGD LRSAM1 LRSAM1 CTSA CTSA ADRA1A ADRA1A STAT3 STAT3 BNIP3 BNIP3 PLEKHF1 PLEKHF1 USP10 USP10 ATF6 ATF6 TRIM14 TRIM14 IFNG IFNG TP53INP2 TP53INP2 K7GG98_PELSI K7GG98_PELSI SMCR8 SMCR8 ATG12 ATG12 FBXW7 FBXW7 LOC102453058 LOC102453058 RPTOR RPTOR TRIB3 TRIB3 UBQLN4 UBQLN4 SLC7A5 SLC7A5 TSC2 TSC2 WDR24 WDR24 TP53 TP53 HSPB8 HSPB8 POLDIP2 POLDIP2 LRRK2 LRRK2 ATG14 ATG14 PIP4K2B PIP4K2B SESN2 SESN2 TSC1 TSC1 USP13 USP13 STING1 STING1 TSPO2 TSPO2 TSPO TSPO LOC102459066 LOC102459066 PRKAA1 PRKAA1 FOXK1 FOXK1 DCAF12 DCAF12 RRAGB RRAGB K7G131_PELSI K7G131_PELSI PIK3C3 PIK3C3 TPCN2 TPCN2 NPRL3 NPRL3 NOD1 NOD1 UVRAG UVRAG PHF23 PHF23 ATP13A2 ATP13A2 DRAM2 DRAM2 CISD1 CISD1 TMEM39A TMEM39A VPS13D VPS13D RMC1 RMC1 ATM ATM SIRT1 SIRT1 PIP4K2A PIP4K2A WDR6 WDR6 MTCL1 MTCL1 DDIT3 DDIT3 K7FDM1_PELSI K7FDM1_PELSI PRKN PRKN RAB3GAP1 RAB3GAP1 KLHL22 KLHL22 PINK1 PINK1 VDAC1 VDAC1 TMEM39B TMEM39B K7FAV3_PELSI K7FAV3_PELSI WAC WAC SMG1 SMG1 SEC22B SEC22B EPM2A EPM2A SH3BP4 SH3BP4 K7F8W3_PELSI K7F8W3_PELSI RRAGC RRAGC TRIM8 TRIM8 PRKAA2 PRKAA2 K7F713_PELSI K7F713_PELSI SNX4 SNX4 IL10 IL10 DCN DCN BCL2 BCL2 MTMR3 MTMR3 RNF41 RNF41 TMEM59 TMEM59 LDLRAD1 LDLRAD1 CPTP CPTP STK11 STK11 ATG5 ATG5 ATG101 ATG101 PIK3R4 PIK3R4 CLEC16A CLEC16A UFL1 UFL1 SIRT2 SIRT2 HTR2B HTR2B RUBCN RUBCN K7F2N5_PELSI K7F2N5_PELSI DAP DAP IL10RA IL10RA RNF152 RNF152 K7F0T6_PELSI K7F0T6_PELSI TRIM32 TRIM32 TBC1D25 TBC1D25 FOXO1 FOXO1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FOXK2Forkhead box K2. (533 aa)
FBXO7F-box protein 7. (459 aa)
TIGARUncharacterized protein. (274 aa)
TPCN1Two pore segment channel 1. (764 aa)
SNX30Sorting nexin family member 30. (468 aa)
SCFD1Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family. (617 aa)
TFEBTranscription factor EB. (480 aa)
KIAA0408KIAA0408. (690 aa)
K7FVY0_PELSIUncharacterized protein. (603 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1015 aa)
BOKBCL2 family apoptosis regulator BOK. (216 aa)
SNX7Sorting nexin 7. (442 aa)
FOXO3Fork-head domain-containing protein. (587 aa)
GPR137BG protein-coupled receptor 137B. (385 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (413 aa)
MFSD8Major facilitator superfamily domain containing 8. (481 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1358 aa)
SESN1Sestrin 1. (553 aa)
MTMR4Myotubularin related protein 4. (1148 aa)
PAFAH1B2Platelet activating factor acetylhydrolase 1b catalytic subunit 2. (229 aa)
BAG3BCL2 associated athanogene 3. (558 aa)
WDR41WD repeat domain 41. (438 aa)
K7GBN9_PELSIUncharacterized protein. (418 aa)
DRAM1DNA damage regulated autophagy modulator 1. (237 aa)
K7G6G8_PELSIUncharacterized protein. (175 aa)
SUPT5HTranscription elongation factor SPT5. (1089 aa)
LZTS1Leucine zipper tumor suppressor 1. (617 aa)
DEPDC5DEP domain-containing protein. (1592 aa)
HTTHuntingtin. (3096 aa)
XBP1Uncharacterized protein. (292 aa)
RB1CC1RB1 inducible coiled-coil 1. (1591 aa)
C9orf72C9orf72-SMCR8 complex subunit. (481 aa)
FLCNUDENN FLCN/SMCR8-type domain-containing protein. (579 aa)
FEZ2Fasciculation and elongation protein zeta 2. (292 aa)
BCL2L11BCL2 like 11. (225 aa)
K7FN03_PELSIProtein kinase domain-containing protein. (449 aa)
K7FNI3_PELSIUncharacterized protein. (524 aa)
FYCO1RUN domain-containing protein. (956 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1030 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (419 aa)
LEPRLeptin receptor. (1150 aa)
RAB3GAP2RAB3 GTPase activating non-catalytic protein subunit 2. (1397 aa)
MTMR9Myotubularin related protein 9. (550 aa)
CISD2CDGSH iron sulfur domain 2. (136 aa)
MTORSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2522 aa)
SESN3Sestrin 3. (496 aa)
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (738 aa)
SPTLC1Serine palmitoyltransferase long chain base subunit 1. (475 aa)
NPRL2NPR2 like, GATOR1 complex subunit. (385 aa)
K7FGV8_PELSIProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (336 aa)
K7FGU8_PELSIPIPK domain-containing protein. (360 aa)
K7FGU4_PELSIUncharacterized protein. (196 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1301 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (573 aa)
SCOCShort coiled-coil protein. (97 aa)
PARLRhomboid domain-containing protein. (189 aa)
FEZ1Fasciculation and elongation protein zeta 1. (392 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (236 aa)
ATG2AAutophagy related 2A. (2002 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1328 aa)
BMFBcl2 modifying factor. (193 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (562 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (422 aa)
FBXW9F-box and WD repeat domain containing 9. (462 aa)
RRAGDRas related GTP binding D. (393 aa)
LRSAM1Leucine rich repeat and sterile alpha motif containing 1. (732 aa)
CTSACarboxypeptidase; Belongs to the peptidase S10 family. (383 aa)
ADRA1AAdrenoceptor alpha 1A. (467 aa)
STAT3Signal transducer and activator of transcription. (707 aa)
BNIP3BCL2 interacting protein 3. (205 aa)
PLEKHF1Pleckstrin homology and FYVE domain containing 1. (275 aa)
USP10Ubiquitin specific peptidase 10; Belongs to the peptidase C19 family. (531 aa)
ATF6Activating transcription factor 6. (593 aa)
TRIM14Tripartite motif containing 14. (377 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (168 aa)
TP53INP2Tumor protein p53 inducible nuclear protein 2. (218 aa)
K7GG98_PELSIUncharacterized protein. (438 aa)
SMCR8SMCR8-C9orf72 complex subunit. (932 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (143 aa)
FBXW7F-box and WD repeat domain containing 7. (610 aa)
LOC102453058Uncharacterized protein. (771 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1245 aa)
TRIB3Uncharacterized protein. (135 aa)
UBQLN4Ubiquilin 4. (566 aa)
SLC7A5Solute carrier family 7 member 5. (428 aa)
TSC2TSC complex subunit 2. (1816 aa)
WDR24WD repeat domain 24. (789 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (390 aa)
HSPB8Heat shock protein family B (small) member 8; Belongs to the small heat shock protein (HSP20) family. (203 aa)
POLDIP2DNA polymerase delta interacting protein 2. (338 aa)
LRRK2Leucine rich repeat kinase 2. (2537 aa)
ATG14Autophagy related 14. (393 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (364 aa)
SESN2Uncharacterized protein. (443 aa)
TSC1TSC complex subunit 1. (1168 aa)
USP13Ubiquitin carboxyl-terminal hydrolase. (862 aa)
STING1Transmembrane protein 173. (379 aa)
TSPO2Translocator protein 2. (164 aa)
TSPOTranslocator protein. (164 aa)
LOC102459066Uncharacterized protein. (196 aa)
PRKAA1Non-specific serine/threonine protein kinase. (560 aa)
FOXK1Forkhead box K1. (541 aa)
DCAF12DDB1 and CUL4 associated factor 12. (450 aa)
RRAGBRas related GTP binding B. (313 aa)
K7G131_PELSIMyotubularin phosphatase domain-containing protein. (524 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (864 aa)
TPCN2Uncharacterized protein. (684 aa)
NPRL3NPR3 like, GATOR1 complex subunit. (491 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (950 aa)
UVRAGUV radiation resistance associated. (659 aa)
PHF23PHD finger protein 23. (347 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (751 aa)
DRAM2DNA damage regulated autophagy modulator 2. (257 aa)
CISD1CDGSH iron sulfur domain 1. (108 aa)
TMEM39ATransmembrane protein 39A. (488 aa)
VPS13DVacuolar protein sorting 13 homolog D. (4398 aa)
RMC1Regulator of MON1-CCZ1. (656 aa)
ATMNon-specific serine/threonine protein kinase. (3061 aa)
SIRT1Deacetylase sirtuin-type domain-containing protein. (607 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (358 aa)
WDR6WD_REPEATS_REGION domain-containing protein. (564 aa)
MTCL1Microtubule crosslinking factor 1. (1512 aa)
DDIT3DNA damage inducible transcript 3. (159 aa)
K7FDM1_PELSIUncharacterized protein. (254 aa)
PRKNRBR-type E3 ubiquitin transferase. (119 aa)
RAB3GAP1RAB3 GTPase activating protein catalytic subunit 1. (967 aa)
KLHL22BTB domain-containing protein. (638 aa)
PINK1PTEN induced kinase 1. (364 aa)
VDAC1Voltage dependent anion channel 1. (283 aa)
TMEM39BTransmembrane protein 39B. (493 aa)
K7FAV3_PELSIUncharacterized protein. (249 aa)
WACWW domain containing adaptor with coiled-coil. (643 aa)
SMG1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3388 aa)
SEC22BSEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family. (128 aa)
EPM2AEPM2A glucan phosphatase, laforin. (233 aa)
SH3BP4SH3 domain binding protein 4. (964 aa)
K7F8W3_PELSISMG1_N domain-containing protein. (180 aa)
RRAGCRas related GTP binding C. (338 aa)
TRIM8Tripartite motif containing 8. (555 aa)
PRKAA2Non-specific serine/threonine protein kinase. (520 aa)
K7F713_PELSIIF rod domain-containing protein; Belongs to the intermediate filament family. (164 aa)
SNX4Sorting nexin 4. (441 aa)
IL10Interleukin 10. (161 aa)
DCNDecorin; May affect the rate of fibrils formation. (356 aa)
BCL2BCL2 apoptosis regulator. (232 aa)
MTMR3Myotubularin related protein 3. (1188 aa)
RNF41Ring finger protein 41. (316 aa)
TMEM59Transmembrane protein 59. (309 aa)
LDLRAD1Low density lipoprotein receptor class A domain containing 1. (173 aa)
CPTPCeramide-1-phosphate transfer protein. (214 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (373 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (276 aa)
ATG101Autophagy related 101. (230 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1359 aa)
CLEC16AFPL domain-containing protein. (593 aa)
UFL1UFM1 specific ligase 1. (769 aa)
SIRT2NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (372 aa)
HTR2B5-hydroxytryptamine receptor 2B. (433 aa)
RUBCNRUN domain-containing protein. (620 aa)
K7F2N5_PELSIDUF4206 domain-containing protein. (233 aa)
DAPUncharacterized protein. (87 aa)
IL10RAInterfer-bind domain-containing protein. (647 aa)
RNF152Ring finger protein 152. (203 aa)
K7F0T6_PELSIUncharacterized protein. (375 aa)
TRIM32Tripartite motif containing 32. (647 aa)
TBC1D25TBC1 domain family member 25. (388 aa)
FOXO1FOXO-TAD domain-containing protein. (401 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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