(43 nodes) Inclusion body network (Pelodiscus sinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HOXD3	Homeobox D3. (414 aa)
	K7F543_PELSI	Uncharacterized protein. (506 aa)
	URB2	URB2 ribosome biogenesis homolog. (1551 aa)
	BAG5	BCL2 associated athanogene 5. (450 aa)
	HERPUD1	Homocysteine inducible ER protein with ubiquitin like domain 1. (295 aa)
	HSPB7	Heat shock protein family B (small) member 7; Belongs to the small heat shock protein (HSP20) family. (162 aa)
	K7FZR1_PELSI	BTB domain-containing protein. (295 aa)
	SLF1	SMC5-SMC6 complex localization factor 1. (1062 aa)
	TRIM37	Tripartite motif containing 37. (966 aa)
	TPR	Translocated promoter region, nuclear basket protein. (1848 aa)
	XRN2	5'-3' exoribonuclease; Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II. (768 aa)
	AGL	Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase. (1531 aa)
	HTT	Huntingtin. (3096 aa)
	WDFY3	WD repeat and FYVE domain containing 3. (3495 aa)
	ARIH1	RBR-type E3 ubiquitin transferase. (434 aa)
	NUP98	Nucleoporin 98. (1801 aa)
	RNF32	Ring finger protein 32. (371 aa)
	NUP153	Nucleoporin 153. (1427 aa)
	FBXO7	F-box protein 7. (459 aa)
	K7FXL0_PELSI	Uncharacterized protein. (191 aa)
	SFMBT2	SLED domain-containing protein. (613 aa)
	ATF4	Activating transcription factor 4. (356 aa)
	LRRK2	Leucine rich repeat kinase 2. (2537 aa)
	SNCB	Synuclein beta. (70 aa)
	SQSTM1	Sequestosome 1. (437 aa)
	TRIM66	Uncharacterized protein. (536 aa)
	K7FNC1_PELSI	BBC domain-containing protein. (501 aa)
	NBN	Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (778 aa)
	RANBP2	RAN binding protein 2. (3029 aa)
	K7FIX1_PELSI	GSAP-16 domain-containing protein. (151 aa)
	ATXN1	Ataxin 1. (679 aa)
	RAD18	RAD18 E3 ubiquitin protein ligase. (500 aa)
	PSEN1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
	ATXN1L	Ataxin 1 like. (677 aa)
	EDEM1	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (433 aa)
	K7FDM1_PELSI	Uncharacterized protein. (254 aa)
	PRKN	RBR-type E3 ubiquitin transferase. (119 aa)
	KLHL14	BTB domain-containing protein. (615 aa)
	ZBTB14	Zinc finger and BTB domain containing 14. (448 aa)
	RANGAP1	Ran GTPase activating protein 1. (579 aa)
	MECOM-2	Uncharacterized protein. (126 aa)
	HOXC9	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (256 aa)
	PRDM16	PR/SET domain 16. (1155 aa)

Your Current Organism:

Pelodiscus sinensis

NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATF4	HERPUD1	ENSPSIP00000012303	ENSPSIP00000013035	Activating transcription factor 4.	Homocysteine inducible ER protein with ubiquitin like domain 1.	0.517
ATXN1	ATXN1L	ENSPSIP00000007784	ENSPSIP00000006920	Ataxin 1.	Ataxin 1 like.	0.900
ATXN1	HTT	ENSPSIP00000007784	ENSPSIP00000016925	Ataxin 1.	Huntingtin.	0.563
ATXN1L	ATXN1	ENSPSIP00000006920	ENSPSIP00000007784	Ataxin 1 like.	Ataxin 1.	0.900
ATXN1L	HTT	ENSPSIP00000006920	ENSPSIP00000016925	Ataxin 1 like.	Huntingtin.	0.426
EDEM1	HERPUD1	ENSPSIP00000006439	ENSPSIP00000013035	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	Homocysteine inducible ER protein with ubiquitin like domain 1.	0.426
FBXO7	K7FDM1_PELSI	ENSPSIP00000012892	ENSPSIP00000006131	F-box protein 7.	Uncharacterized protein.	0.505
FBXO7	PRKN	ENSPSIP00000012892	ENSPSIP00000006123	F-box protein 7.	RBR-type E3 ubiquitin transferase.	0.505
HERPUD1	ATF4	ENSPSIP00000013035	ENSPSIP00000012303	Homocysteine inducible ER protein with ubiquitin like domain 1.	Activating transcription factor 4.	0.517
HERPUD1	EDEM1	ENSPSIP00000013035	ENSPSIP00000006439	Homocysteine inducible ER protein with ubiquitin like domain 1.	alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.	0.426
HTT	ATXN1	ENSPSIP00000016925	ENSPSIP00000007784	Huntingtin.	Ataxin 1.	0.563
HTT	ATXN1L	ENSPSIP00000016925	ENSPSIP00000006920	Huntingtin.	Ataxin 1 like.	0.426
HTT	K7FDM1_PELSI	ENSPSIP00000016925	ENSPSIP00000006131	Huntingtin.	Uncharacterized protein.	0.539
HTT	K7FIX1_PELSI	ENSPSIP00000016925	ENSPSIP00000007981	Huntingtin.	GSAP-16 domain-containing protein.	0.500
HTT	PRKN	ENSPSIP00000016925	ENSPSIP00000006123	Huntingtin.	RBR-type E3 ubiquitin transferase.	0.539
HTT	PSEN1	ENSPSIP00000016925	ENSPSIP00000007093	Huntingtin.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.405
HTT	SQSTM1	ENSPSIP00000016925	ENSPSIP00000010714	Huntingtin.	Sequestosome 1.	0.726
K7FDM1_PELSI	FBXO7	ENSPSIP00000006131	ENSPSIP00000012892	Uncharacterized protein.	F-box protein 7.	0.505
K7FDM1_PELSI	HTT	ENSPSIP00000006131	ENSPSIP00000016925	Uncharacterized protein.	Huntingtin.	0.539
K7FDM1_PELSI	K7FIX1_PELSI	ENSPSIP00000006131	ENSPSIP00000007981	Uncharacterized protein.	GSAP-16 domain-containing protein.	0.733