STRINGSTRING
CFAP126 CFAP126 PROM2 PROM2 FZD6 FZD6 ITPK1 ITPK1 ATP4B ATP4B ACY3 ACY3 SHROOM3 SHROOM3 ADCY8 ADCY8 ATP1B3 ATP1B3 ANXA1 ANXA1 PARD6A PARD6A PRKCZ PRKCZ SLC1A1 SLC1A1 ABCG8 ABCG8 K7G1R8_PELSI K7G1R8_PELSI PDZD3 PDZD3 PRKCI PRKCI SLC7A5 SLC7A5 MPDZ MPDZ ATP12A ATP12A K7FN99_PELSI K7FN99_PELSI SLC22A18 SLC22A18 JAG1 JAG1 KCNQ1 KCNQ1 SHROOM2 SHROOM2 ATP4A ATP4A SLC6A6 SLC6A6 K7FPY4_PELSI K7FPY4_PELSI GPR143 GPR143 ATP6V1B2 ATP6V1B2 SLC9A4 SLC9A4 SLC4A11 SLC4A11 K7FIC0_PELSI K7FIC0_PELSI ZMYND10 ZMYND10 SLC3A1 SLC3A1 P2RX2 P2RX2 PSEN1 PSEN1 CLDN1 CLDN1 PATJ PATJ CRB2 CRB2 SLC7A9 SLC7A9 UPK1A UPK1A FAT1 FAT1 K7FFD5_PELSI K7FFD5_PELSI K7FFA6_PELSI K7FFA6_PELSI USH2A USH2A RAPGEF2 RAPGEF2 AQP5 AQP5 SLC39A14 SLC39A14 SLC4A7 SLC4A7 SHANK2 SHANK2 PDPN PDPN K7FCA8_PELSI K7FCA8_PELSI STK26 STK26 PARD6G PARD6G SLC5A2 SLC5A2 RIPOR2 RIPOR2 PARD3B PARD3B K7FB03_PELSI K7FB03_PELSI DPP4 DPP4 CIB1 CIB1 LOC102458614 LOC102458614 KCNK2 KCNK2 SLC4A10 SLC4A10 SLC9A3R1 SLC9A3R1 GJA1 GJA1 AJAP1 AJAP1 SLC5A12 SLC5A12 SLC9A1 SLC9A1 SLC16A8 SLC16A8 CD34 CD34 EMP2 EMP2 CTSB CTSB MIP MIP PTPRO PTPRO SLC26A9 SLC26A9 SLC3A2 SLC3A2 SCNN1D SCNN1D UPK1B UPK1B LOC102452629 LOC102452629 K7F3C6_PELSI K7F3C6_PELSI CLDND1 CLDND1 K7F2T9_PELSI K7F2T9_PELSI FXYD1 FXYD1 SLC23A2 SLC23A2 KCNE1 KCNE1 LOC106731356 LOC106731356 K7EZI8_PELSI K7EZI8_PELSI K7EZ34_PELSI K7EZ34_PELSI F2RL2 F2RL2 PKHD1 PKHD1 KCNE4 KCNE4 SCNN1B SCNN1B KIAA1614 KIAA1614 KCNK1 KCNK1 DLL1 DLL1 K7FSL9_PELSI K7FSL9_PELSI SCNN1G SCNN1G DSTYK DSTYK OSMR OSMR SLC22A5 SLC22A5 MAL2 MAL2 ABCG5 ABCG5 K7FTR4_PELSI K7FTR4_PELSI SLC39A8 SLC39A8 SLC6A19 SLC6A19 SLC29A4 SLC29A4 AKR1A1 AKR1A1 K7FUW8_PELSI K7FUW8_PELSI NOTCH1 NOTCH1 K7FWF2_PELSI K7FWF2_PELSI SLC16A3 SLC16A3 SLC2A13 SLC2A13 THY1 THY1 SORBS2 SORBS2 K7FXZ1_PELSI K7FXZ1_PELSI AQP6 AQP6 LOC102445630 LOC102445630 K7FYF9_PELSI K7FYF9_PELSI AKAP7 AKAP7 SLC6A18 SLC6A18 SLC12A3 SLC12A3 PODXL PODXL EXOC1 EXOC1 C1QTNF5 C1QTNF5 PARD3 PARD3 TEK TEK K7G2I6_PELSI K7G2I6_PELSI PROM1 PROM1 RHCG RHCG ABCC5 ABCC5 ATP1B2 ATP1B2 CUBN CUBN PDGFRB PDGFRB K7G565_PELSI K7G565_PELSI DRAM2 DRAM2 ADAM17 ADAM17 SLC22A4 SLC22A4 K7G6E9_PELSI K7G6E9_PELSI SLC26A6 SLC26A6 SLC26A4 SLC26A4 SLC7A1 SLC7A1 ECRG4 ECRG4 MSN MSN AQP1 AQP1 SLC12A2 SLC12A2 AMN AMN LOC102462623 LOC102462623 K7G8M9_PELSI K7G8M9_PELSI LMO7 LMO7 CYBRD1 CYBRD1 MPP5 MPP5 SLC23A1 SLC23A1 DDR2 DDR2 DUOX2 DUOX2 SLC12A1 SLC12A1 EPCAM EPCAM PLPP1 PLPP1 K7GCA4_PELSI K7GCA4_PELSI HIP1R HIP1R PLB1 PLB1 PARD6B PARD6B FN1 FN1 SLC34A2 SLC34A2 CIB3 CIB3 K7GDT8_PELSI K7GDT8_PELSI SLC26A3 SLC26A3 ATP6V1G1 ATP6V1G1 MREG MREG SCNN1A SCNN1A CFTR CFTR K7GFC6_PELSI K7GFC6_PELSI ATP6V1A ATP6V1A SLC9A3R2 SLC9A3R2 STXBP3 STXBP3 PSEN2 PSEN2 UPK3A UPK3A SLC46A1 SLC46A1 SLC6A20 SLC6A20 ADCY10 ADCY10 CPO CPO EZR EZR CD36 CD36 FZD3 FZD3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CFAP126Cilia and flagella associated protein 126. (120 aa)
PROM2Prominin 2. (836 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (715 aa)
ITPK1Inositol-tetrakisphosphate 1-kinase. (406 aa)
ATP4BSodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (200 aa)
ACY3Aminoacylase 3. (313 aa)
SHROOM3Shroom family member 3. (2029 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1070 aa)
ATP1B3ATPase Na+/K+ transporting subunit beta 3. (166 aa)
ANXA1Annexin. (342 aa)
PARD6APar-6 family cell polarity regulator alpha. (241 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (592 aa)
SLC1A1Amino acid transporter. (504 aa)
ABCG8ATP binding cassette subfamily G member 8. (677 aa)
K7G1R8_PELSIUncharacterized protein. (808 aa)
PDZD3PDZ domain containing 3. (370 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (607 aa)
SLC7A5Solute carrier family 7 member 5. (428 aa)
MPDZMultiple PDZ domain crumbs cell polarity complex component. (1712 aa)
ATP12ASodium/potassium-transporting ATPase subunit alpha. (1036 aa)
K7FN99_PELSIUncharacterized protein. (116 aa)
SLC22A18MFS domain-containing protein. (311 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1184 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (374 aa)
SHROOM2Shroom family member 2. (1412 aa)
ATP4ASodium/potassium-transporting ATPase subunit alpha. (1033 aa)
SLC6A6Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (620 aa)
K7FPY4_PELSIUncharacterized protein. (156 aa)
GPR143Uncharacterized protein. (294 aa)
ATP6V1B2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (502 aa)
SLC9A4NEXCaM_BD domain-containing protein. (167 aa)
SLC4A11Solute carrier family 4 member 11. (847 aa)
K7FIC0_PELSIIntegrin beta; Belongs to the integrin beta chain family. (739 aa)
ZMYND10Zinc finger MYND-type containing 10. (394 aa)
SLC3A1Solute carrier family 3 member 1. (673 aa)
P2RX2P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (365 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (201 aa)
PATJUncharacterized protein. (960 aa)
CRB2Uncharacterized protein. (1404 aa)
SLC7A9Solute carrier family 7 member 9. (488 aa)
UPK1AUroplakin 1A; Belongs to the tetraspanin (TM4SF) family. (258 aa)
FAT1FAT atypical cadherin 1. (4655 aa)
K7FFD5_PELSIUncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
K7FFA6_PELSIUncharacterized protein. (568 aa)
USH2AUsherin. (4999 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1644 aa)
AQP5Aquaporin 5; Belongs to the MIP/aquaporin (TC 1.A.8) family. (265 aa)
SLC39A14Solute carrier family 39 member 14. (482 aa)
SLC4A7Anion exchange protein. (1210 aa)
SHANK2SAM domain-containing protein. (1171 aa)
PDPNUncharacterized protein. (145 aa)
K7FCA8_PELSIAKAP7_NLS domain-containing protein. (230 aa)
STK26Serine/threonine kinase 26. (416 aa)
PARD6GPar-6 family cell polarity regulator gamma. (384 aa)
SLC5A2Solute carrier family 5 member 2; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (596 aa)
RIPOR2PL48 domain-containing protein. (886 aa)
PARD3BPar-3 family cell polarity regulator beta. (1062 aa)
K7FB03_PELSIUncharacterized protein. (184 aa)
DPP4Uncharacterized protein; Belongs to the peptidase S9B family. (760 aa)
CIB1Calcium and integrin binding 1. (190 aa)
LOC102458614Uncharacterized protein. (824 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (410 aa)
SLC4A10Anion exchange protein. (1130 aa)
SLC9A3R1SLC9A3 regulator 1. (313 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (381 aa)
AJAP1Adherens junctions associated protein 1. (407 aa)
SLC5A12Solute carrier family 5 member 12; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (627 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (773 aa)
SLC16A8Solute carrier family 16 member 8. (542 aa)
CD34CD34 molecule. (197 aa)
EMP2Epithelial membrane protein 2. (166 aa)
CTSBCathepsin B; Belongs to the peptidase C1 family. (330 aa)
MIPMajor intrinsic protein of lens fiber; Belongs to the MIP/aquaporin (TC 1.A.8) family. (266 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1221 aa)
SLC26A9Solute carrier family 26 member 9; DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (807 aa)
SLC3A2Solute carrier family 3 member 2. (541 aa)
SCNN1DUncharacterized protein; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (400 aa)
UPK1BTetraspanin. (260 aa)
LOC102452629Aminopeptidase. (948 aa)
K7F3C6_PELSIPeptidase_M1 domain-containing protein. (530 aa)
CLDND1Claudin domain containing 1. (256 aa)
K7F2T9_PELSIABC transporter domain-containing protein. (663 aa)
FXYD1FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (92 aa)
SLC23A2Solute carrier family 23 member 2. (658 aa)
KCNE1Uncharacterized protein. (126 aa)
LOC106731356Uncharacterized protein. (620 aa)
K7EZI8_PELSIUncharacterized protein. (57 aa)
K7EZ34_PELSIATP-synt_ab domain-containing protein. (38 aa)
F2RL2Coagulation factor II thrombin receptor like 2. (353 aa)
PKHD1Uncharacterized protein. (49 aa)
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (163 aa)
SCNN1BAmiloride-sensitive sodium channel subunit beta; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. (607 aa)
KIAA1614KIAA1614. (886 aa)
KCNK1Potassium channel subfamily K member. (336 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (726 aa)
K7FSL9_PELSILink domain-containing protein. (389 aa)
SCNN1GAmiloride-sensitive sodium channel subunit gamma; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. (669 aa)
DSTYKDual serine/threonine and tyrosine protein kinase. (852 aa)
OSMROncostatin M receptor. (983 aa)
SLC22A5Solute carrier family 22 member 5. (436 aa)
MAL2Mal, T cell differentiation protein 2 (gene/pseudogene). (139 aa)
ABCG5ATP binding cassette subfamily G member 5. (606 aa)
K7FTR4_PELSIVacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (463 aa)
SLC39A8Solute carrier family 39 member 8. (467 aa)
SLC6A19Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (636 aa)
SLC29A4Solute carrier family 29 member 4. (509 aa)
AKR1A1Aldo-keto reductase family 1 member A1. (327 aa)
K7FUW8_PELSIUncharacterized protein. (92 aa)
NOTCH1Notch receptor 1. (2494 aa)
K7FWF2_PELSIUncharacterized protein. (267 aa)
SLC16A3Solute carrier family 16 member 3. (534 aa)
SLC2A13Solute carrier family 2 member 13; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (646 aa)
THY1Thy-1 cell surface antigen. (182 aa)
SORBS2Sorbin and SH3 domain containing 2. (1222 aa)
K7FXZ1_PELSIKCNQ_channel domain-containing protein. (99 aa)
AQP6Aquaporin 6; Belongs to the MIP/aquaporin (TC 1.A.8) family. (264 aa)
LOC102445630Uncharacterized protein. (493 aa)
K7FYF9_PELSIIon_trans domain-containing protein; Belongs to the potassium channel family. (300 aa)
AKAP7A-kinase anchoring protein 7. (319 aa)
SLC6A18Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (617 aa)
SLC12A3SLC12 domain-containing protein. (122 aa)
PODXLPodocalyxin like. (535 aa)
EXOC1Exocyst complex component 1. (522 aa)
C1QTNF5C1q and TNF related 5. (241 aa)
PARD3Par-3 family cell polarity regulator. (1264 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
K7G2I6_PELSIUncharacterized protein. (1570 aa)
PROM1Prominin 1. (859 aa)
RHCGRh family C glycoprotein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily. (469 aa)
ABCC5ATP binding cassette subfamily C member 5. (1435 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (329 aa)
CUBNCubilin. (3680 aa)
PDGFRBPlatelet derived growth factor receptor beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1068 aa)
K7G565_PELSIABC2_membrane domain-containing protein. (376 aa)
DRAM2DNA damage regulated autophagy modulator 2. (257 aa)
ADAM17ADAM metallopeptidase domain 17. (836 aa)
SLC22A4Solute carrier family 22 member 4. (297 aa)
K7G6E9_PELSIABC transporter domain-containing protein. (661 aa)
SLC26A6Solute carrier family 26 member 6. (725 aa)
SLC26A4Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (777 aa)
SLC7A1Solute carrier family 7 member 1. (628 aa)
ECRG4ECRG4 augurin precursor. (147 aa)
MSNMoesin. (580 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
SLC12A2Solute carrier family 12 member 2. (1054 aa)
AMNAmnion associated transmembrane protein. (481 aa)
LOC102462623ABC transporter domain-containing protein. (621 aa)
K7G8M9_PELSICH_2 domain-containing protein. (204 aa)
LMO7LIM domain 7. (1535 aa)
CYBRD1Cytochrome b reductase 1. (284 aa)
MPP5Membrane palmitoylated protein 5; Belongs to the MAGUK family. (676 aa)
SLC23A1Solute carrier family 23 member 1. (586 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (887 aa)
DUOX2Dual oxidase 2. (1543 aa)
SLC12A1Solute carrier family 12 member 1. (1096 aa)
EPCAMEpithelial cell adhesion molecule. (303 aa)
PLPP1Phospholipid phosphatase 1. (222 aa)
K7GCA4_PELSIPDZ domain-containing protein. (101 aa)
HIP1RHuntingtin interacting protein 1 related. (1043 aa)
PLB1Phospholipase B1. (1473 aa)
PARD6BPar-6 family cell polarity regulator beta. (373 aa)
FN1Fibronectin 1. (2389 aa)
SLC34A2Solute carrier family 34 member 2. (676 aa)
CIB3Calcium and integrin binding family member 3. (181 aa)
K7GDT8_PELSIATP-synt_ab domain-containing protein. (322 aa)
SLC26A3Chloride anion exchanger; Chloride/bicarbonate exchanger. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (755 aa)
ATP6V1G1V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (135 aa)
MREGMelanoregulin. (152 aa)
SCNN1AAmiloride-sensitive sodium channel subunit alpha; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. (642 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1015 aa)
K7GFC6_PELSIPDZ domain-containing protein. (81 aa)
ATP6V1AATPase H+ transporting V1 subunit A. (617 aa)
SLC9A3R2Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (356 aa)
STXBP3Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (639 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (387 aa)
UPK3AUroplakin 3A. (277 aa)
SLC46A1Solute carrier family 46 member 1. (388 aa)
SLC6A20Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (591 aa)
ADCY10Adenylate cyclase 10. (1612 aa)
CPOCarboxypeptidase O. (417 aa)
EZREzrin. (600 aa)
CD36CD36 molecule; Belongs to the CD36 family. (479 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (403 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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