STRINGSTRING
TTK TTK NLK NLK DCAF1 DCAF1 CDC42BPG CDC42BPG ACVR1B ACVR1B TGFBR1 TGFBR1 OXSR1 OXSR1 CDK10 CDK10 TGFBR2 TGFBR2 DYRK1B DYRK1B CSNK2A2 CSNK2A2 HIPK1 HIPK1 LOC102457599 LOC102457599 DYRK3 DYRK3 TNKS TNKS BCL2 BCL2 STK11 STK11 K7FRX4_PELSI K7FRX4_PELSI TTBK1 TTBK1 PRKDC PRKDC CSNK2A1 CSNK2A1 CDK1 CDK1 KIAA1549 KIAA1549 CDC42BPB CDC42BPB DYRK2 DYRK2 ACVR1 ACVR1 DYRK4 DYRK4 GSK3B GSK3B ULK1 ULK1 ROCK1 ROCK1 K7FKZ4_PELSI K7FKZ4_PELSI MTOR MTOR CHEK1 CHEK1 VRK1 VRK1 STK39 STK39 HIPK3 HIPK3 DYRK1A DYRK1A PDPK1 PDPK1 LRRK2 LRRK2 ROCK2 ROCK2 CSNK2B CSNK2B K7FGV8_PELSI K7FGV8_PELSI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TTKTTK protein kinase. (881 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (527 aa)
DCAF1DDB1 and CUL4 associated factor 1. (1505 aa)
CDC42BPGCDC42 binding protein kinase gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1593 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
OXSR1Protein kinase domain-containing protein. (502 aa)
CDK10Cyclin dependent kinase 10; Belongs to the protein kinase superfamily. (338 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (584 aa)
DYRK1BDual specificity tyrosine phosphorylation regulated kinase 1B. (416 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (340 aa)
HIPK1Homeodomain interacting protein kinase 1. (1210 aa)
LOC102457599TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
DYRK3Dual specificity tyrosine phosphorylation regulated kinase 3. (579 aa)
TNKSPoly [ADP-ribose] polymerase. (1133 aa)
BCL2BCL2 apoptosis regulator. (232 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (373 aa)
K7FRX4_PELSIProtein kinase domain-containing protein. (267 aa)
TTBK1Tau tubulin kinase 1. (1262 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4133 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (303 aa)
KIAA1549KIAA1549. (1683 aa)
CDC42BPBCDC42 binding protein kinase beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1711 aa)
DYRK2Dual specificity tyrosine phosphorylation regulated kinase 2. (598 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (511 aa)
DYRK4Dual specificity tyrosine phosphorylation regulated kinase 4. (357 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (419 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1030 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1358 aa)
K7FKZ4_PELSIProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (386 aa)
MTORSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2522 aa)
CHEK1Checkpoint kinase 1. (454 aa)
VRK1VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily. (412 aa)
STK39Serine/threonine kinase 39. (430 aa)
HIPK3Homeodomain interacting protein kinase 3. (1193 aa)
DYRK1ADual specificity tyrosine phosphorylation regulated kinase 1A. (754 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (559 aa)
LRRK2Leucine rich repeat kinase 2. (2537 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1360 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (216 aa)
K7FGV8_PELSIProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (336 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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