STRINGSTRING
TGFA TGFA IGF2 IGF2 ELP4 ELP4 CKS2 CKS2 CCNF CCNF CCNI2 CCNI2 LOC102449564 LOC102449564 ALS2 ALS2 CCNO CCNO CCND2 CCND2 PRKAG2 PRKAG2 NRG1 NRG1 PRKAR2B PRKAR2B STRADA STRADA CCNJL CCNJL CCNB2 CCNB2 CDKN1B CDKN1B PRKRIP1 PRKRIP1 CD40LG CD40LG ALK ALK CCNB1 CCNB1 FGFR1OP FGFR1OP RICTOR RICTOR SPRY2 SPRY2 CCND1 CCND1 MBIP MBIP ALK-2 ALK-2 HEXIM1 HEXIM1 HSPB1 HSPB1 CCNE2 CCNE2 PRKAR1A PRKAR1A CCND3 CCND3 FAM20A FAM20A P2RX7 P2RX7 GAS6 GAS6 DGKQ DGKQ EPGN EPGN CDKN1C CDKN1C EREG EREG K7FND2_PELSI K7FND2_PELSI AREG AREG BTC BTC MLST8 MLST8 STRADB STRADB TRIB1 TRIB1 GPRC5A GPRC5A CCNT2 CCNT2 CCNJ CCNJ BMPR1A BMPR1A K7FJ02_PELSI K7FJ02_PELSI LOC102445440 LOC102445440 K7FIQ5_PELSI K7FIQ5_PELSI K7FI94_PELSI K7FI94_PELSI IBTK IBTK SPRED1 SPRED1 DELE1 DELE1 DBF4 DBF4 CDKN2C CDKN2C CCNG1 CCNG1 MOB1A MOB1A PAK2 PAK2 BMPR1B BMPR1B CCNYL1 CCNYL1 MTCP1 MTCP1 CCNL1 CCNL1 PRKAR1B PRKAR1B MACROH2A1 MACROH2A1 CCNL2 CCNL2 PKIA PKIA INKA2 INKA2 DUS2 DUS2 TPX2 TPX2 MOB3C MOB3C STAP1 STAP1 STK11 STK11 CCNT1 CCNT1 CCNC CCNC CCNA1 CCNA1 ALKAL2 ALKAL2 ARMC9 ARMC9 CAB39L CAB39L DNAJC3 DNAJC3 DUSP19 DUSP19 K7F1M4_PELSI K7F1M4_PELSI SPRY3 SPRY3 NKPD1 NKPD1 ITPRIP ITPRIP K7EW96_PELSI K7EW96_PELSI RPLP1 RPLP1 GHRL GHRL ELP3 ELP3 NCAPG2 NCAPG2 TRIB3 TRIB3 RPTOR RPTOR KIDINS220 KIDINS220 MAP3K13 MAP3K13 CCNY CCNY GREM1 GREM1 K7GH67_PELSI K7GH67_PELSI CCNI CCNI SMCR8 SMCR8 PRKAR2A PRKAR2A CCNG2 CCNG2 CCNA2 CCNA2 CCNE1 CCNE1 K7GCT6_PELSI K7GCT6_PELSI CAB39 CAB39 CRYAB CRYAB CDKN2A CDKN2A MOB3A MOB3A TOM1L1 TOM1L1 ERCC6 ERCC6 MOB3B MOB3B LTK LTK MOB2 MOB2 ALKAL1 ALKAL1 HBEGF HBEGF TRIB2 TRIB2 SPDYA SPDYA NRG2 NRG2 GCN1 GCN1 CHP1 CHP1 PIK3CA PIK3CA SPRY4 SPRY4 MNAT1 MNAT1 MOB1B MOB1B GPRC5B GPRC5B ABI1 ABI1 BMPR2 BMPR2 WNT11 WNT11 CCNK CCNK SH3BP5 SH3BP5 ANKRD54 ANKRD54 YWHAB YWHAB PARP16 PARP16 PKIG PKIG CCNH CCNH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFATransforming growth factor alpha. (162 aa)
IGF2Insulin like growth factor 2. (186 aa)
ELP4Elongator acetyltransferase complex subunit 4. (407 aa)
CKS2Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (64 aa)
CCNFCyclin F; Belongs to the cyclin family. (775 aa)
CCNI2Cyclin I family member 2; Belongs to the cyclin family. (366 aa)
LOC102449564Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (388 aa)
ALS2Alsin Rho guanine nucleotide exchange factor ALS2. (1629 aa)
CCNOCyclin O; Belongs to the cyclin family. (258 aa)
CCND2Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (291 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (564 aa)
NRG1Neuregulin 1. (533 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (309 aa)
STRADASTE20 related adaptor alpha. (430 aa)
CCNJLCyclin J like; Belongs to the cyclin family. (473 aa)
CCNB2Cyclin B2; Belongs to the cyclin family. (400 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
PRKRIP1PRKR interacting protein 1. (144 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (273 aa)
ALKTyrosine-protein kinase receptor. (813 aa)
CCNB1Cyclin B1; Belongs to the cyclin family. (410 aa)
FGFR1OPFGFR1 oncogene partner. (360 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1715 aa)
SPRY2Sprouty RTK signaling antagonist 2. (313 aa)
CCND1Cyclin D1; Belongs to the cyclin family. (292 aa)
MBIPMAP3K12 binding inhibitory protein 1. (299 aa)
ALK-2Uncharacterized protein. (386 aa)
HEXIM1HEXIM P-TEFb complex subunit 1. (221 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (216 aa)
CCNE2Cyclin E2; Belongs to the cyclin family. (405 aa)
PRKAR1AProtein kinase cAMP-dependent type I regulatory subunit alpha. (382 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (297 aa)
FAM20AFAM20A golgi associated secretory pathway pseudokinase. (412 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (566 aa)
GAS6Growth arrest specific 6. (403 aa)
DGKQDiacylglycerol kinase. (853 aa)
EPGNEpithelial mitogen. (109 aa)
CDKN1CCyclin dependent kinase inhibitor 1C. (229 aa)
EREGEpiregulin. (154 aa)
K7FND2_PELSIUncharacterized protein. (178 aa)
AREGAmphiregulin. (212 aa)
BTCBetacellulin. (154 aa)
MLST8MTOR associated protein, LST8 homolog. (271 aa)
STRADBSTE20 related adaptor beta. (416 aa)
TRIB1Tribbles pseudokinase 1. (257 aa)
GPRC5AG_PROTEIN_RECEP_F3_4 domain-containing protein. (358 aa)
CCNT2Cyclin T2. (319 aa)
CCNJCyclin J; Belongs to the cyclin family. (383 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (525 aa)
K7FJ02_PELSIPhosphatidylinositol 3-kinase catalytic subunit type 3. (787 aa)
LOC102445440Uncharacterized protein. (454 aa)
K7FIQ5_PELSIPI3K-ABD domain-containing protein; Belongs to the PI3/PI4-kinase family. (211 aa)
K7FI94_PELSIANK_REP_REGION domain-containing protein. (145 aa)
IBTKInhibitor of Bruton tyrosine kinase. (1358 aa)
SPRED1Sprouty related EVH1 domain containing 1. (213 aa)
DELE1Uncharacterized protein. (525 aa)
DBF4DBF4 zinc finger. (675 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (169 aa)
CCNG1Cyclin G1; Belongs to the cyclin family. (295 aa)
MOB1AMOB kinase activator 1A. (171 aa)
PAK2Non-specific serine/threonine protein kinase. (520 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (534 aa)
CCNYL1Cyclin Y like 1; Belongs to the cyclin family. (350 aa)
MTCP1Uncharacterized protein. (72 aa)
CCNL1Cyclin L1; Belongs to the cyclin family. (443 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)
MACROH2A1Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
CCNL2Cyclin L2; Belongs to the cyclin family. (305 aa)
PKIAcAMP-dependent protein kinase inhibitor; Belongs to the PKI family. (76 aa)
INKA2Inka box actin regulator 2. (357 aa)
DUS2Dihydrouridine synthase 2. (508 aa)
TPX2TPX2 microtubule nucleation factor. (741 aa)
MOB3CMOB kinase activator 3C. (218 aa)
STAP1Signal transducing adaptor family member 1. (280 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (373 aa)
CCNT1Cyclin T1. (657 aa)
CCNCCyclin C; Belongs to the cyclin family. (283 aa)
CCNA1Cyclin A1; Belongs to the cyclin family. (416 aa)
ALKAL2ALK and LTK ligand 2. (152 aa)
ARMC9Armadillo repeat containing 9. (815 aa)
CAB39LCalcium binding protein 39 like. (334 aa)
DNAJC3DnaJ heat shock protein family (Hsp40) member C3. (461 aa)
DUSP19Dual specificity phosphatase 19; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (215 aa)
K7F1M4_PELSIUncharacterized protein. (56 aa)
SPRY3Sprouty RTK signaling antagonist 3. (290 aa)
NKPD1NTPase KAP family P-loop domain containing 1. (453 aa)
ITPRIPInositol 1,4,5-trisphosphate receptor interacting protein. (429 aa)
K7EW96_PELSIUncharacterized protein. (63 aa)
RPLP1Ribosomal protein lateral stalk subunit P1; Belongs to the eukaryotic ribosomal protein P1/P2 family. (112 aa)
GHRLGhrelin and obestatin prepropeptide. (118 aa)
ELP3Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (542 aa)
NCAPG2Non-SMC condensin II complex subunit G2. (1142 aa)
TRIB3Uncharacterized protein. (135 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1245 aa)
KIDINS220Kinase D interacting substrate 220. (1765 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase. (873 aa)
CCNYCyclin Y; Belongs to the cyclin family. (287 aa)
GREM1Gremlin. (182 aa)
K7GH67_PELSIINCENP_N domain-containing protein. (522 aa)
CCNICyclin I; Belongs to the cyclin family. (390 aa)
SMCR8SMCR8-C9orf72 complex subunit. (932 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (304 aa)
CCNG2Cyclin G2; Belongs to the cyclin family. (346 aa)
CCNA2Cyclin A2; Belongs to the cyclin family. (362 aa)
CCNE1Cyclin E1; Belongs to the cyclin family. (404 aa)
K7GCT6_PELSIINCENP_ARK-bind domain-containing protein. (850 aa)
CAB39Calcium binding protein 39. (341 aa)
CRYABCrystallin alpha B; Belongs to the small heat shock protein (HSP20) family. (195 aa)
CDKN2ACyclin dependent kinase inhibitor 2A. (139 aa)
MOB3AMOB kinase activator 3A. (202 aa)
TOM1L1Target of myb1 like 1 membrane trafficking protein; Belongs to the TOM1 family. (474 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1273 aa)
MOB3BMOB kinase activator 3B. (216 aa)
LTKTyrosine-protein kinase receptor. (1183 aa)
MOB2MOB kinase activator 2. (265 aa)
ALKAL1ALK and LTK ligand 1. (148 aa)
HBEGFHeparin binding EGF like growth factor. (139 aa)
TRIB2Tribbles pseudokinase 2. (343 aa)
SPDYASpeedy/RINGO cell cycle regulator family member A. (311 aa)
NRG2Neuregulin 2. (494 aa)
GCN1GCN1 activator of EIF2AK4. (2669 aa)
CHP1Calcineurin like EF-hand protein 1. (195 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
SPRY4Sprouty RTK signaling antagonist 4. (299 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
MOB1BMOB kinase activator 1B. (244 aa)
GPRC5BG protein-coupled receptor class C group 5 member B. (413 aa)
ABI1Abl interactor 1. (476 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1042 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
CCNKCyclin K; Belongs to the cyclin family. (573 aa)
SH3BP5SH3 domain binding protein 5. (382 aa)
ANKRD54Ankyrin repeat domain 54. (194 aa)
YWHABTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (244 aa)
PARP16Poly [ADP-ribose] polymerase. (329 aa)
PKIGcAMP-dependent protein kinase inhibitor gamma. (76 aa)
CCNHCyclin H; Belongs to the cyclin family. (363 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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