(27 nodes) Cytosolic small ribosomal subunit network (Pelodiscus sinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102446692	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family. (245 aa)
	RPS27	40S ribosomal protein S27. (82 aa)
	RPS16	Uncharacterized protein; Belongs to the universal ribosomal protein uS9 family. (166 aa)
	LOC102459951	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (143 aa)
	LOC102451666	Ribosomal protein S23. (202 aa)
	MRPS11	Mitochondrial ribosomal protein S11; Belongs to the universal ribosomal protein uS11 family. (204 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (140 aa)
	RPS13	Ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family. (149 aa)
	DHX29	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1363 aa)
	RPS3	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa)
	RPS3A	40S ribosomal protein S3a; Belongs to the eukaryotic ribosomal protein eS1 family. (264 aa)
	RPS8	40S ribosomal protein S8; Belongs to the eukaryotic ribosomal protein eS8 family. (208 aa)
	RPS2	Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family. (297 aa)
	RPS9	Ribosomal protein S9. (185 aa)
	RPS14	Ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family. (151 aa)
	EIF2A	Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (586 aa)
	K7FB63_PELSI	Uncharacterized protein. (178 aa)
	RPS10	S10_plectin domain-containing protein. (153 aa)
	RPS21	40S ribosomal protein S21; Belongs to the eukaryotic ribosomal protein eS21 family. (83 aa)
	RPSA	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family. (329 aa)
	EIF2D	Eukaryotic translation initiation factor 2D. (600 aa)
	RPS25	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family. (130 aa)
	RPS12	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (132 aa)
	RPS26	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family. (115 aa)
	RPS7	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family. (194 aa)
	RPS15	Ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family. (168 aa)
	RPS29	Uncharacterized protein. (49 aa)

Your Current Organism:

Pelodiscus sinensis

NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DHX29	EIF2D	ENSPSIP00000013001	ENSPSIP00000003739	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Eukaryotic translation initiation factor 2D.	0.519
DHX29	LOC102451666	ENSPSIP00000013001	ENSPSIP00000017996	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Ribosomal protein S23.	0.506
DHX29	RPS10	ENSPSIP00000013001	ENSPSIP00000005162	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	S10_plectin domain-containing protein.	0.417
DHX29	RPS12	ENSPSIP00000013001	ENSPSIP00000003630	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	40S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family.	0.459
DHX29	RPS13	ENSPSIP00000013001	ENSPSIP00000013251	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family.	0.524
DHX29	RPS14	ENSPSIP00000013001	ENSPSIP00000006431	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.	0.594
DHX29	RPS15	ENSPSIP00000013001	ENSPSIP00000002828	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family.	0.428
DHX29	RPS2	ENSPSIP00000013001	ENSPSIP00000007325	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.	0.588
DHX29	RPS25	ENSPSIP00000013001	ENSPSIP00000003713	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family.	0.458
DHX29	RPS26	ENSPSIP00000013001	ENSPSIP00000003221	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.	0.433
DHX29	RPS27	ENSPSIP00000013001	ENSPSIP00000019138	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	40S ribosomal protein S27.	0.577
DHX29	RPS3	ENSPSIP00000013001	ENSPSIP00000009770	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family.	0.440
DHX29	RPS3A	ENSPSIP00000013001	ENSPSIP00000007916	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	40S ribosomal protein S3a; Belongs to the eukaryotic ribosomal protein eS1 family.	0.580
DHX29	RPS7	ENSPSIP00000013001	ENSPSIP00000003114	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	40S ribosomal protein S7; Belongs to the eukaryotic ribosomal protein eS7 family.	0.661
DHX29	RPS9	ENSPSIP00000013001	ENSPSIP00000006445	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	Ribosomal protein S9.	0.681
DHX29	RPSA	ENSPSIP00000013001	ENSPSIP00000004444	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family.	0.495
EIF2D	DHX29	ENSPSIP00000003739	ENSPSIP00000013001	Eukaryotic translation initiation factor 2D.	ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily.	0.519
EIF2D	K7FB63_PELSI	ENSPSIP00000003739	ENSPSIP00000005273	Eukaryotic translation initiation factor 2D.	Uncharacterized protein.	0.521
EIF2D	LOC102446692	ENSPSIP00000003739	ENSPSIP00000004417	Eukaryotic translation initiation factor 2D.	40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family.	0.696
EIF2D	LOC102451666	ENSPSIP00000003739	ENSPSIP00000017996	Eukaryotic translation initiation factor 2D.	Ribosomal protein S23.	0.655