(13 nodes) Heparin metabolic process network (Pelodiscus sinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HPSE	Heparanase. (482 aa)
	SLC10A7	Sodium/bile acid cotransporter; Does not show transport activity towards bile acids or steroid sulfates; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. (323 aa)
	EDNRA	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (421 aa)
	NDST1	N-deacetylase and N-sulfotransferase 1. (867 aa)
	EDNRB	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (310 aa)
	NDST4	N-deacetylase and N-sulfotransferase 4. (873 aa)
	NDST3	N-deacetylase and N-sulfotransferase 3. (873 aa)
	LOC102449550	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (450 aa)
	EXT2	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (719 aa)
	IDUA	Iduronidase alpha-L-. (635 aa)
	K7G968_PELSI	Uncharacterized protein. (781 aa)
	GLCE	Glucuronic acid epimerase. (617 aa)
	HS2ST1	Uncharacterized protein. (356 aa)

Your Current Organism:

Pelodiscus sinensis

NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDNRA	EDNRB	ENSPSIP00000006983	ENSPSIP00000007173	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family.	0.965
EDNRA	LOC102449550	ENSPSIP00000006983	ENSPSIP00000013346	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.966
EDNRB	EDNRA	ENSPSIP00000007173	ENSPSIP00000006983	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.965
EDNRB	LOC102449550	ENSPSIP00000007173	ENSPSIP00000013346	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.900
EXT2	HS2ST1	ENSPSIP00000013946	ENSPSIP00000017816	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.	Uncharacterized protein.	0.563
EXT2	K7G968_PELSI	ENSPSIP00000013946	ENSPSIP00000016829	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.	Uncharacterized protein.	0.450
GLCE	HS2ST1	ENSPSIP00000017210	ENSPSIP00000017816	Glucuronic acid epimerase.	Uncharacterized protein.	0.688
GLCE	K7G968_PELSI	ENSPSIP00000017210	ENSPSIP00000016829	Glucuronic acid epimerase.	Uncharacterized protein.	0.522
GLCE	NDST3	ENSPSIP00000017210	ENSPSIP00000011901	Glucuronic acid epimerase.	N-deacetylase and N-sulfotransferase 3.	0.936
GLCE	NDST4	ENSPSIP00000017210	ENSPSIP00000011455	Glucuronic acid epimerase.	N-deacetylase and N-sulfotransferase 4.	0.936
HS2ST1	EXT2	ENSPSIP00000017816	ENSPSIP00000013946	Uncharacterized protein.	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.	0.563
HS2ST1	GLCE	ENSPSIP00000017816	ENSPSIP00000017210	Uncharacterized protein.	Glucuronic acid epimerase.	0.688
HS2ST1	K7G968_PELSI	ENSPSIP00000017816	ENSPSIP00000016829	Uncharacterized protein.	Uncharacterized protein.	0.432
K7G968_PELSI	EXT2	ENSPSIP00000016829	ENSPSIP00000013946	Uncharacterized protein.	Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family.	0.450
K7G968_PELSI	GLCE	ENSPSIP00000016829	ENSPSIP00000017210	Uncharacterized protein.	Glucuronic acid epimerase.	0.522
K7G968_PELSI	HS2ST1	ENSPSIP00000016829	ENSPSIP00000017816	Uncharacterized protein.	Uncharacterized protein.	0.432
LOC102449550	EDNRA	ENSPSIP00000013346	ENSPSIP00000006983	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family.	0.966
LOC102449550	EDNRB	ENSPSIP00000013346	ENSPSIP00000007173	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family.	0.900
NDST3	GLCE	ENSPSIP00000011901	ENSPSIP00000017210	N-deacetylase and N-sulfotransferase 3.	Glucuronic acid epimerase.	0.936
NDST3	NDST4	ENSPSIP00000011901	ENSPSIP00000011455	N-deacetylase and N-sulfotransferase 3.	N-deacetylase and N-sulfotransferase 4.	0.900