STRINGSTRING
GPR89B GPR89B LOC102460285 LOC102460285 IL12B IL12B GLI3 GLI3 PKNOX1 PKNOX1 BATF BATF IL15 IL15 SP3 SP3 TNFSF8 TNFSF8 RC3H1 RC3H1 STAT3 STAT3 CD8A CD8A PAX1 PAX1 CD4 CD4 DLL4 DLL4 CD74 CD74 GATA3 GATA3 HLX HLX TP53 TP53 PTGER4 PTGER4 BCL11B BCL11B SYK SYK CD3E CD3E TESPA1 TESPA1 BRAF BRAF IL18R1 IL18R1 RABL3 RABL3 ABL2 ABL2 RORA RORA K7FWT7_PELSI K7FWT7_PELSI TOX TOX THEMIS THEMIS IL4R IL4R IRF1 IRF1 TSC1 TSC1 IL6 IL6 RIPK2 RIPK2 IKZF3 IKZF3 IL7R IL7R FOXN1 FOXN1 LEPR LEPR RORC RORC CD83 CD83 K7FN03_PELSI K7FN03_PELSI KIT KIT SOX13 SOX13 ANXA1 ANXA1 PTPRC PTPRC CARD11 CARD11 MTOR MTOR ABL1 ABL1 RSAD2 RSAD2 TMEM98 TMEM98 K7FD12_PELSI K7FD12_PELSI RC3H2 RC3H2 EOMES EOMES TCF7 TCF7 ZAP70 ZAP70 FADD FADD JAG2 JAG2 SASH3 SASH3 PTPN2 PTPN2 TRAF3IP2 TRAF3IP2 IL7 IL7 ZBTB1 ZBTB1 LEF1 LEF1 BCL2 BCL2 NCAPH2 NCAPH2 WNT1 WNT1 JMJD6 JMJD6 STK11 STK11 ATG5 ATG5 CCR7 CCR7 CTNNB1 CTNNB1 RAG2 RAG2 RAG1 RAG1 RHOH RHOH LIG4 LIG4 K7EZ53_PELSI K7EZ53_PELSI K7EZ43_PELSI K7EZ43_PELSI GPR183 GPR183 GPR18 GPR18
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GPR89BUncharacterized protein. (456 aa)
LOC102460285C-type lectin domain family 4 member G. (297 aa)
IL12BInterleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (321 aa)
GLI3GLI family zinc finger 3. (1575 aa)
PKNOX1PBX/knotted 1 homeobox 1. (478 aa)
BATFBasic leucine zipper ATF-like transcription factor. (115 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (172 aa)
SP3Sp3 transcription factor. (705 aa)
TNFSF8TNF superfamily member 8; Belongs to the tumor necrosis factor family. (219 aa)
RC3H1Ring finger and CCCH-type domains 1. (1127 aa)
STAT3Signal transducer and activator of transcription. (707 aa)
CD8ACD8a molecule. (266 aa)
PAX1Uncharacterized protein. (185 aa)
CD4Ig-like domain-containing protein. (458 aa)
DLL4Delta like canonical Notch ligand 4. (684 aa)
CD74CD74 molecule. (293 aa)
GATA3GATA binding protein 3. (425 aa)
HLXH2.0 like homeobox. (354 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (390 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (472 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (883 aa)
SYKTyrosine-protein kinase. (445 aa)
CD3EUncharacterized protein. (152 aa)
TESPA1Thymocyte expressed, positive selection associated 1. (329 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (760 aa)
IL18R1Interleukin 18 receptor 1. (569 aa)
RABL3RAB, member of RAS oncogene family like 3. (236 aa)
ABL2Tyrosine-protein kinase. (1103 aa)
RORARAR related orphan receptor A. (459 aa)
K7FWT7_PELSIProtein kinase domain-containing protein. (174 aa)
TOXThymocyte selection associated high mobility group box. (527 aa)
THEMISThymocyte selection associated. (585 aa)
IL4RFibronectin type-III domain-containing protein. (763 aa)
IRF1Interferon regulatory factor. (316 aa)
TSC1TSC complex subunit 1. (1168 aa)
IL6Interleukin 6. (211 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (562 aa)
IKZF3IKAROS family zinc finger 3. (456 aa)
IL7RInterleukin 7 receptor. (419 aa)
FOXN1Forkhead box N1. (662 aa)
LEPRLeptin receptor. (1150 aa)
RORCRAR related orphan receptor C. (555 aa)
CD83CD83 molecule. (164 aa)
K7FN03_PELSIProtein kinase domain-containing protein. (449 aa)
KITKIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (947 aa)
SOX13SRY-box transcription factor 13. (614 aa)
ANXA1Annexin. (342 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (736 aa)
CARD11Caspase recruitment domain family member 11. (1164 aa)
MTORSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2522 aa)
ABL1Tyrosine-protein kinase. (1127 aa)
RSAD2Radical S-adenosyl methionine domain containing 2. (347 aa)
TMEM98Transmembrane protein 98. (177 aa)
K7FD12_PELSIUncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (546 aa)
RC3H2Ring finger and CCCH-type domains 2. (1191 aa)
EOMESEomesodermin. (571 aa)
TCF7Transcription factor 7. (342 aa)
ZAP70Tyrosine-protein kinase. (614 aa)
FADDFas associated via death domain. (191 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1262 aa)
SASH3SAM domain-containing protein. (126 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (394 aa)
TRAF3IP2SEFIR domain-containing protein. (556 aa)
IL7Uncharacterized protein. (144 aa)
ZBTB1Zinc finger and BTB domain containing 1. (640 aa)
LEF1Lymphoid enhancer binding protein 1 (LEF-1) homologue. (398 aa)
BCL2BCL2 apoptosis regulator. (232 aa)
NCAPH2Non-SMC condensin II complex subunit H2. (570 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (374 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (373 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (276 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (377 aa)
CTNNB1Uncharacterized protein. (778 aa)
RAG2Recombination activating 2. (533 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1039 aa)
RHOHRas homolog family member H. (191 aa)
LIG4DNA ligase. (912 aa)
K7EZ53_PELSIG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (333 aa)
K7EZ43_PELSIG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (315 aa)
GPR183G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (356 aa)
GPR18G protein-coupled receptor 18; Belongs to the G-protein coupled receptor 1 family. (331 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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