STRINGSTRING
EXOSC9 EXOSC9 TGFBR1 TGFBR1 TRPV2 TRPV2 SUPV3L1 SUPV3L1 RPTOR RPTOR IST1 IST1 AKAP6 AKAP6 FN1 FN1 MFSD2A MFSD2A ADNP ADNP FXN FXN INO80 INO80 SEMA4D SEMA4D ZNF639 ZNF639 ADAM17 ADAM17 BMPR2 BMPR2 LOC102457242 LOC102457242 USP47 USP47 K7G3B3_PELSI K7G3B3_PELSI K7G2N3_PELSI K7G2N3_PELSI LGI1 LGI1 CDKL5 CDKL5 RUFY3 RUFY3 DERL3 DERL3 SYT4 SYT4 GOLGA4 GOLGA4 NOL12 NOL12 MAP2K5 MAP2K5 ANAPC2 ANAPC2 ISLR ISLR ISLR2 ISLR2 SMURF1 SMURF1 ADAM10 ADAM10 EFNA5 EFNA5 FGFR1OP FGFR1OP CDKN2AIP CDKN2AIP DBNL DBNL WNT3A WNT3A PSMD10 PSMD10 K7FNR2_PELSI K7FNR2_PELSI DDX49 DDX49 MAPT MAPT TGFB2 TGFB2 LOC102462376 LOC102462376 PLAA PLAA LOC102451232 LOC102451232 SYT1 SYT1 CRABP2 CRABP2 ZFYVE27 ZFYVE27 MTOR MTOR CYFIP1 CYFIP1 SYT2 SYT2 BRAT1 BRAT1 HDGFL2 HDGFL2 EXOSC2 EXOSC2 SEMA7A SEMA7A ARMC12 ARMC12 SMAD7 SMAD7 ITSN2 ITSN2 K7FDM1_PELSI K7FDM1_PELSI PRKN PRKN KLHL22 KLHL22 DISC1 DISC1 MUL1 MUL1 MTPN MTPN RND2 RND2 ADNP2 ADNP2 F2 F2 EDN1 EDN1 WNT3 WNT3 SYT17 SYT17 SLC9A1 SLC9A1 BCL2 BCL2 HPN HPN TRIM32 TRIM32 NGF NGF SFRP2 SFRP2 BDNF BDNF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EXOSC9Exosome component 9. (385 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (733 aa)
SUPV3L1Suv3 like RNA helicase. (802 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1245 aa)
IST1IST1 factor associated with ESCRT-III. (378 aa)
AKAP6A-kinase anchoring protein 6. (2314 aa)
FN1Fibronectin 1. (2389 aa)
MFSD2AMajor facilitator superfamily domain containing 2A. (503 aa)
ADNPActivity dependent neuroprotector homeobox. (1124 aa)
FXNFrataxin. (159 aa)
INO80INO80 complex ATPase subunit. (1561 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (857 aa)
ZNF639Zinc finger protein 639. (482 aa)
ADAM17ADAM metallopeptidase domain 17. (836 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1042 aa)
LOC102457242COMM domain-containing protein. (182 aa)
USP47Uncharacterized protein. (816 aa)
K7G3B3_PELSIUncharacterized protein. (206 aa)
K7G2N3_PELSIC2 domain-containing protein. (121 aa)
LGI1Leucine rich glioma inactivated 1. (551 aa)
CDKL5Cyclin dependent kinase like 5. (644 aa)
RUFY3RUN and FYVE domain containing 3. (635 aa)
DERL3Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. (156 aa)
SYT4Synaptotagmin 4. (425 aa)
GOLGA4Golgin A4. (2233 aa)
NOL12Uncharacterized protein. (215 aa)
MAP2K5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (413 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (771 aa)
ISLRImmunoglobulin superfamily containing leucine rich repeat. (339 aa)
ISLR2Immunoglobulin superfamily containing leucine rich repeat 2. (551 aa)
SMURF1SMAD specific E3 ubiquitin protein ligase 1. (556 aa)
ADAM10ADAM metallopeptidase domain 10. (749 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (191 aa)
FGFR1OPFGFR1 oncogene partner. (360 aa)
CDKN2AIPCDKN2A interacting protein. (501 aa)
DBNLDrebrin like. (411 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (241 aa)
PSMD10Proteasome 26S subunit, non-ATPase 10. (190 aa)
K7FNR2_PELSIUncharacterized protein; Belongs to the semaphorin family. (557 aa)
DDX49DEAD-box helicase 49; Belongs to the DEAD box helicase family. (439 aa)
MAPTMicrotubule-associated protein. (736 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
LOC102462376Uncharacterized protein; Belongs to the semaphorin family. (720 aa)
PLAAPhospholipase A2 activating protein. (739 aa)
LOC102451232Glyco_transf_64 domain-containing protein. (203 aa)
SYT1Synaptotagmin 1. (424 aa)
CRABP2Cellular retinoic acid-binding protein 1; Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors. (138 aa)
ZFYVE27Zinc finger FYVE-type containing 27. (268 aa)
MTORSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2522 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
SYT2Uncharacterized protein. (436 aa)
BRAT1BRCA1 associated ATM activator 1. (838 aa)
HDGFL2HDGF like 2. (526 aa)
EXOSC2Exosome component 2. (294 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (618 aa)
ARMC12Armadillo repeat containing 12. (342 aa)
SMAD7Mothers against decapentaplegic homolog. (387 aa)
ITSN2Intersectin 2. (1694 aa)
K7FDM1_PELSIUncharacterized protein. (254 aa)
PRKNRBR-type E3 ubiquitin transferase. (119 aa)
KLHL22BTB domain-containing protein. (638 aa)
DISC1DISC1 scaffold protein. (635 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
MTPNMyotrophin. (118 aa)
RND2Rho family GTPase 2. (211 aa)
ADNP2ADNP homeobox 2. (1048 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (611 aa)
EDN1Endothelin 1. (204 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (356 aa)
SYT17Synaptotagmin 17. (375 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (773 aa)
BCL2BCL2 apoptosis regulator. (232 aa)
HPNHepsin; Belongs to the peptidase S1 family. (417 aa)
TRIM32Tripartite motif containing 32. (647 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (242 aa)
SFRP2Secreted frizzled related protein 2. (150 aa)
BDNFBrain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (246 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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