STRINGSTRING
CDKN2C CDKN2C SFRP2 SFRP2 LOC102453784 LOC102453784 PRDM11-2 PRDM11-2 BMP10 BMP10 PI16 PI16 SPART SPART PTPRJ PTPRJ STK11 STK11 RERG RERG BCL2 BCL2 ST7L ST7L DCBLD2 DCBLD2 NDUFS3 NDUFS3 IP6K2 IP6K2 TOMM70 TOMM70 GJA1 GJA1 WNT3 WNT3 SH3BP4 SH3BP4 PHB PHB SEMA5B SEMA5B SERPINE2 SERPINE2 OSTN OSTN CDA CDA MUL1 MUL1 CTDP1 CTDP1 SMARCA4 SMARCA4 SMARCA2 SMARCA2 SIRT1 SIRT1 SEMA7A SEMA7A SEMA5A SEMA5A SEMA6B SEMA6B LOC102462376 LOC102462376 TGFB2 TGFB2 K7FNR2_PELSI K7FNR2_PELSI CCN3 CCN3 ULK1 ULK1 CGRRF1 CGRRF1 RB1 RB1 K7FQ62_PELSI K7FQ62_PELSI WNT3A WNT3A PSRC1 PSRC1 FHL1 FHL1 DRAXIN DRAXIN SEMA4F SEMA4F CDKN2AIP CDKN2AIP SESN2 SESN2 MAP2 MAP2 SEMA3G SEMA3G LOC102449564 LOC102449564 FGF13 FGF13 IFRD1 IFRD1 G6PD G6PD DCUN1D3 DCUN1D3 VGLL4 VGLL4 TNR TNR MINAR1 MINAR1 PRDM11 PRDM11 GDF9 GDF9 DAB2 DAB2 TP53 TP53 BCL11A BCL11A WNT11 WNT11 BMPR2 BMPR2 WT1 WT1 MAG MAG DCSTAMP DCSTAMP SEMA4A SEMA4A SLIT2 SLIT2 SEMA4D SEMA4D NME6 NME6 SMAD4 SMAD4 CRLF3 CRLF3 SERTAD1 SERTAD1 FLCN FLCN PPT1 PPT1 NDUFA13 NDUFA13 ULK2 ULK2 ST7 ST7 CAPRIN2 CAPRIN2 GDF2 GDF2 DIP2B DIP2B MSX1 MSX1 SLIT3 SLIT3 SEMA6C SEMA6C RYK RYK SEMA3D SEMA3D TCHP TCHP SEMA3A SEMA3A SEMA3E SEMA3E GREM1 GREM1 K7GHY0_PELSI K7GHY0_PELSI SEMA6D SEMA6D ACVRL1 ACVRL1 INHBA INHBA SEMA6A SEMA6A SERTAD2 SERTAD2 ACVR1B ACVR1B SEMA3C SEMA3C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDKN2CCyclin dependent kinase inhibitor 2C. (169 aa)
SFRP2Secreted frizzled related protein 2. (150 aa)
LOC102453784SERTA domain-containing protein. (282 aa)
PRDM11-2Uncharacterized protein. (710 aa)
BMP10Bone morphogenetic protein 10. (426 aa)
PI16SCP domain-containing protein; Belongs to the CRISP family. (466 aa)
SPARTSpartin. (630 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1341 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (373 aa)
RERGRAS like estrogen regulated growth inhibitor. (199 aa)
BCL2BCL2 apoptosis regulator. (232 aa)
ST7LSuppression of tumorigenicity 7 like. (391 aa)
DCBLD2Discoidin, CUB and LCCL domain containing 2. (691 aa)
NDUFS3NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. (262 aa)
IP6K2Kinase; Belongs to the inositol phosphokinase (IPK) family. (424 aa)
TOMM70Translocase of outer mitochondrial membrane 70. (501 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (381 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (356 aa)
SH3BP4SH3 domain binding protein 4. (964 aa)
PHBProhibitin. (272 aa)
SEMA5BSemaphorin 5B. (1092 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (396 aa)
OSTNOsteocrin. (134 aa)
CDACytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (163 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (759 aa)
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1613 aa)
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1573 aa)
SIRT1Deacetylase sirtuin-type domain-containing protein. (607 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (618 aa)
SEMA5ASemaphorin 5A. (1144 aa)
SEMA6BSemaphorin 6B; Belongs to the semaphorin family. (383 aa)
LOC102462376Uncharacterized protein; Belongs to the semaphorin family. (720 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (413 aa)
K7FNR2_PELSIUncharacterized protein; Belongs to the semaphorin family. (557 aa)
CCN3Cellular communication network factor 3. (351 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1030 aa)
CGRRF1Cell growth regulator with ring finger domain 1. (303 aa)
RB1RB transcriptional corepressor 1. (917 aa)
K7FQ62_PELSIUncharacterized protein. (809 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (241 aa)
PSRC1Proline and serine rich coiled-coil 1. (253 aa)
FHL1Four and a half LIM domains 1. (297 aa)
DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord; Belongs to the draxin family. (343 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (718 aa)
CDKN2AIPCDKN2A interacting protein. (501 aa)
SESN2Uncharacterized protein. (443 aa)
MAP2Microtubule-associated protein. (1868 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (753 aa)
LOC102449564Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (388 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (193 aa)
IFRD1Interferon related developmental regulator 1. (460 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (513 aa)
DCUN1D3DCN1-like protein. (304 aa)
VGLL4Vestigial like family member 4. (295 aa)
TNRTenascin R. (1562 aa)
MINAR1Membrane integral NOTCH2 associated receptor 1. (912 aa)
PRDM11SET domain-containing protein. (471 aa)
GDF9Growth differentiation factor 9. (444 aa)
DAB2DAB adaptor protein 2. (712 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (390 aa)
BCL11ABAF chromatin remodeling complex subunit BCL11A. (796 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1042 aa)
WT1WT1 transcription factor. (415 aa)
MAGMyelin associated glycoprotein. (617 aa)
DCSTAMPDendrocyte expressed seven transmembrane protein. (470 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (769 aa)
SLIT2Slit guidance ligand 2. (1381 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (857 aa)
NME6NME/NM23 nucleoside diphosphate kinase 6; Belongs to the NDK family. (175 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
CRLF3Cytokine receptor like factor 3. (440 aa)
SERTAD1SERTA domain-containing protein. (225 aa)
FLCNUDENN FLCN/SMCR8-type domain-containing protein. (579 aa)
PPT1Palmitoyl-protein thioesterase 1. (267 aa)
NDUFA13NADH:ubiquinone oxidoreductase subunit A13. (113 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1015 aa)
ST7Suppression of tumorigenicity 7. (554 aa)
CAPRIN2Caprin family member 2. (1229 aa)
GDF2Growth differentiation factor 2. (425 aa)
DIP2BDisco interacting protein 2 homolog B. (1555 aa)
MSX1Msh homeobox 1. (299 aa)
SLIT3Slit guidance ligand 3. (1396 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (1016 aa)
RYKReceptor like tyrosine kinase. (541 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (774 aa)
TCHPUncharacterized protein. (499 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (809 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (757 aa)
GREM1Gremlin. (182 aa)
K7GHY0_PELSILRRNT domain-containing protein. (72 aa)
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1078 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (479 aa)
INHBAInhibin subunit beta A. (423 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1027 aa)
SERTAD2SERTA domain containing 2. (318 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (750 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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