STRINGSTRING
STOX1 STOX1 K7GI78_PELSI K7GI78_PELSI LATS1 LATS1 INPP5F INPP5F IFNG IFNG LOC102461384 LOC102461384 BDNF BDNF SFRP2 SFRP2 LOC102450184 LOC102450184 NGF NGF LOC102450014 LOC102450014 NTF3 NTF3 RAMP3 RAMP3 BCL2 BCL2 LIF LIF PDCD10 PDCD10 NTRK2 NTRK2 EPM2A EPM2A TNF TNF MTCP1 MTCP1 PINK1 PINK1 SMYD3 SMYD3 K7FD05_PELSI K7FD05_PELSI FNIP1 FNIP1 RET RET CAPRIN2 CAPRIN2 SH2D3A SH2D3A K7GC99_PELSI K7GC99_PELSI DKK1 DKK1 MLXIPL MLXIPL ERCC6 ERCC6 NCK2 NCK2 PIK3CA PIK3CA VEGFA VEGFA PRKAA1 PRKAA1 MAPKAP1 MAPKAP1 BAK1 BAK1 NSD1 NSD1 SH2D3C SH2D3C BAG4 BAG4 PWP1 PWP1 BDKRB2 BDKRB2 INPP5K INPP5K CSF3 CSF3 BRAF BRAF RICTOR RICTOR IL6 IL6 PTGS2 PTGS2 RIPK2 RIPK2 ATP2B4 ATP2B4 PAQR3 PAQR3 CREBL2 CREBL2 OPRD1 OPRD1 GAS6 GAS6 INPP5J INPP5J K7FN03_PELSI K7FN03_PELSI BCAR3 BCAR3 DMTN DMTN K7FJ02_PELSI K7FJ02_PELSI K7FIQ5_PELSI K7FIQ5_PELSI CAV3 CAV3 RAPGEF3 RAPGEF3 SMAD7 SMAD7 MAD2L2 MAD2L2 FNIP2 FNIP2 LOC102450431 LOC102450431 RPTOR RPTOR DDIT4 DDIT4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STOX1Storkhead box 1. (875 aa)
K7GI78_PELSIHORMA domain-containing protein. (154 aa)
LATS1Large tumor suppressor kinase 1. (970 aa)
INPP5FInositol polyphosphate-5-phosphatase F. (1101 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (168 aa)
LOC102461384Uncharacterized protein; Belongs to the vasopressin/oxytocin family. (165 aa)
BDNFBrain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (246 aa)
SFRP2Secreted frizzled related protein 2. (150 aa)
LOC102450184Uncharacterized protein. (188 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (242 aa)
LOC102450014Uncharacterized protein. (182 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (267 aa)
RAMP3Receptor activity modifying protein 3. (203 aa)
BCL2BCL2 apoptosis regulator. (232 aa)
LIFLIF interleukin 6 family cytokine. (141 aa)
PDCD10Programmed cell death 10. (212 aa)
NTRK2Tyrosine-protein kinase receptor. (814 aa)
EPM2AEPM2A glucan phosphatase, laforin. (233 aa)
TNFTumor necrosis factor. (229 aa)
MTCP1Uncharacterized protein. (72 aa)
PINK1PTEN induced kinase 1. (364 aa)
SMYD3SET domain-containing protein. (265 aa)
K7FD05_PELSIUncharacterized protein. (120 aa)
FNIP1Folliculin interacting protein 1. (1221 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1103 aa)
CAPRIN2Caprin family member 2. (1229 aa)
SH2D3ASH2 domain containing 3A. (578 aa)
K7GC99_PELSIUncharacterized protein. (90 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (283 aa)
MLXIPLMLX interacting protein like. (890 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1273 aa)
NCK2Cytoplasmic protein. (380 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (217 aa)
PRKAA1Non-specific serine/threonine protein kinase. (560 aa)
MAPKAP1MAPK associated protein 1. (522 aa)
BAK1BCL2 antagonist/killer 1. (213 aa)
NSD1Nuclear receptor binding SET domain protein 1. (1899 aa)
SH2D3CSH2 domain containing 3C. (699 aa)
BAG4BCL2 associated athanogene 4. (331 aa)
PWP1PWP1 homolog, endonuclein. (464 aa)
BDKRB2Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (357 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (440 aa)
CSF3Colony stimulating factor 3. (200 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (760 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1715 aa)
IL6Interleukin 6. (211 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (658 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (562 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1215 aa)
PAQR3Progestin and adipoQ receptor family member 3. (311 aa)
CREBL2cAMP responsive element binding protein like 2. (226 aa)
OPRD1Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (290 aa)
GAS6Growth arrest specific 6. (403 aa)
INPP5JIPPc domain-containing protein. (238 aa)
K7FN03_PELSIProtein kinase domain-containing protein. (449 aa)
BCAR3BCAR3 adaptor protein, NSP family member. (823 aa)
DMTNDematin actin binding protein. (401 aa)
K7FJ02_PELSIPhosphatidylinositol 3-kinase catalytic subunit type 3. (787 aa)
K7FIQ5_PELSIPI3K-ABD domain-containing protein; Belongs to the PI3/PI4-kinase family. (211 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (843 aa)
SMAD7Mothers against decapentaplegic homolog. (387 aa)
MAD2L2HORMA domain-containing protein. (211 aa)
FNIP2Folliculin interacting protein 2. (1107 aa)
LOC102450431Uncharacterized protein. (196 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1245 aa)
DDIT4DNA damage inducible transcript 4. (223 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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