STRINGSTRING
RAMP3 RAMP3 NTF3 NTF3 LOC102450014 LOC102450014 NGF NGF SFRP2 SFRP2 BDNF BDNF MAPKAP1 MAPKAP1 VEGFA VEGFA PIK3CA PIK3CA ERCC6 ERCC6 K7GC99_PELSI K7GC99_PELSI SH2D3A SH2D3A CAPRIN2 CAPRIN2 LOC102461384 LOC102461384 IFNG IFNG LATS1 LATS1 K7GI78_PELSI K7GI78_PELSI RPTOR RPTOR BCL2 BCL2 LIF LIF PDCD10 PDCD10 NTRK2 NTRK2 TNF TNF MTCP1 MTCP1 PINK1 PINK1 SMYD3 SMYD3 K7FD05_PELSI K7FD05_PELSI FNIP1 FNIP1 RET RET FNIP2 FNIP2 MAD2L2 MAD2L2 RAPGEF3 RAPGEF3 CAV3 CAV3 K7FIQ5_PELSI K7FIQ5_PELSI K7FJ02_PELSI K7FJ02_PELSI BCAR3 BCAR3 K7FN03_PELSI K7FN03_PELSI GAS6 GAS6 OPRD1 OPRD1 CREBL2 CREBL2 ATP2B4 ATP2B4 RIPK2 RIPK2 PTGS2 PTGS2 IL6 IL6 BRAF BRAF CSF3 CSF3 BAG4 BAG4 SH2D3C SH2D3C
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAMP3Receptor activity modifying protein 3. (203 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (267 aa)
LOC102450014Uncharacterized protein. (182 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (242 aa)
SFRP2Secreted frizzled related protein 2. (150 aa)
BDNFBrain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (246 aa)
MAPKAP1MAPK associated protein 1. (522 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (217 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1273 aa)
K7GC99_PELSIUncharacterized protein. (90 aa)
SH2D3ASH2 domain containing 3A. (578 aa)
CAPRIN2Caprin family member 2. (1229 aa)
LOC102461384Uncharacterized protein; Belongs to the vasopressin/oxytocin family. (165 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (168 aa)
LATS1Large tumor suppressor kinase 1. (970 aa)
K7GI78_PELSIHORMA domain-containing protein. (154 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1245 aa)
BCL2BCL2 apoptosis regulator. (232 aa)
LIFLIF interleukin 6 family cytokine. (141 aa)
PDCD10Programmed cell death 10. (212 aa)
NTRK2Tyrosine-protein kinase receptor. (814 aa)
TNFTumor necrosis factor. (229 aa)
MTCP1Uncharacterized protein. (72 aa)
PINK1PTEN induced kinase 1. (364 aa)
SMYD3SET domain-containing protein. (265 aa)
K7FD05_PELSIUncharacterized protein. (120 aa)
FNIP1Folliculin interacting protein 1. (1221 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1103 aa)
FNIP2Folliculin interacting protein 2. (1107 aa)
MAD2L2HORMA domain-containing protein. (211 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (843 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
K7FIQ5_PELSIPI3K-ABD domain-containing protein; Belongs to the PI3/PI4-kinase family. (211 aa)
K7FJ02_PELSIPhosphatidylinositol 3-kinase catalytic subunit type 3. (787 aa)
BCAR3BCAR3 adaptor protein, NSP family member. (823 aa)
K7FN03_PELSIProtein kinase domain-containing protein. (449 aa)
GAS6Growth arrest specific 6. (403 aa)
OPRD1Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (290 aa)
CREBL2cAMP responsive element binding protein like 2. (226 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1215 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (562 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (658 aa)
IL6Interleukin 6. (211 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (760 aa)
CSF3Colony stimulating factor 3. (200 aa)
BAG4BCL2 associated athanogene 4. (331 aa)
SH2D3CSH2 domain containing 3C. (699 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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