10 items (Pelodiscus sinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GCLC	Glutamate-cysteine ligase catalytic subunit. (537 aa)
	APPL2	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (643 aa)
	SIRT2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (372 aa)
	IL10	Interleukin 10. (161 aa)
	CREB1	cAMP responsive element binding protein 1. (327 aa)
	MED1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1574 aa)
	APPL1	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (708 aa)
	LGMN	Legumain. (411 aa)
	GCLM	Glutamate-cysteine ligase modifier subunit. (273 aa)
	NRP1	Neuropilin; Belongs to the neuropilin family. (916 aa)

Your Current Organism:

Pelodiscus sinensis

NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APPL1	APPL2	ENSPSIP00000007726	ENSPSIP00000018146	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	0.995
APPL2	APPL1	ENSPSIP00000018146	ENSPSIP00000007726	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	0.995
CREB1	IL10	ENSPSIP00000005798	ENSPSIP00000003748	cAMP responsive element binding protein 1.	Interleukin 10.	0.481
GCLC	GCLM	ENSPSIP00000013994	ENSPSIP00000009058	Glutamate-cysteine ligase catalytic subunit.	Glutamate-cysteine ligase modifier subunit.	0.999
GCLM	GCLC	ENSPSIP00000009058	ENSPSIP00000013994	Glutamate-cysteine ligase modifier subunit.	Glutamate-cysteine ligase catalytic subunit.	0.999
IL10	CREB1	ENSPSIP00000003748	ENSPSIP00000005798	Interleukin 10.	cAMP responsive element binding protein 1.	0.481