STRINGSTRING
PPP1R3C PPP1R3C PPARA PPARA DDIT4 DDIT4 ZBTB7A ZBTB7A RUBCNL RUBCNL STAT3 STAT3 CDK1 CDK1 PASK PASK MLXIPL MLXIPL FLCN FLCN LOC102448206 LOC102448206 ARL2 ARL2 PRXL2C PRXL2C PIK3CA PIK3CA MTOR MTOR IDE IDE PRKAA1 PRKAA1 JMJD8 JMJD8 TP53 TP53 PPP1R3A PPP1R3A PNPT1 PNPT1 OPN3 OPN3 IGF2 IGF2 IFNAR1 IFNAR1 PPARGC1A PPARGC1A INPP5K INPP5K TIGAR TIGAR ETFBKMT ETFBKMT EIF6 EIF6 K7FWM9_PELSI K7FWM9_PELSI FAM214A FAM214A AK4 AK4 PPP1R3D PPP1R3D LOC102445473 LOC102445473 LOC102451702 LOC102451702 K7F011_PELSI K7F011_PELSI K7F0C8_PELSI K7F0C8_PELSI K7F0I9_PELSI K7F0I9_PELSI K7F0L6_PELSI K7F0L6_PELSI PPP1R3B PPP1R3B K7F1W5_PELSI K7F1W5_PELSI K7F1Z8_PELSI K7F1Z8_PELSI ZBTB20 ZBTB20 OGT OGT NOA1 NOA1 PRDM16 PRDM16 TACO1 TACO1 K7FA62_PELSI K7FA62_PELSI K7FAK1_PELSI K7FAK1_PELSI EP300 EP300 MECOM-2 MECOM-2 PDE12 PDE12 NDUFA4 NDUFA4 PINK1 PINK1 TRAP1 TRAP1 PSEN1 PSEN1 COX7A2 COX7A2 HTR2A HTR2A DNAJC15 DNAJC15 P2RX7 P2RX7 SIRT6 SIRT6 COX7A2L COX7A2L COA8 COA8 K7FJ02_PELSI K7FJ02_PELSI K7FIQ5_PELSI K7FIQ5_PELSI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP1R3CProtein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (330 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
DDIT4DNA damage inducible transcript 4. (223 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (552 aa)
RUBCNLRubicon like autophagy enhancer. (774 aa)
STAT3Signal transducer and activator of transcription. (707 aa)
CDK1Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (303 aa)
PASKPAS domain containing serine/threonine kinase. (1317 aa)
MLXIPLMLX interacting protein like. (890 aa)
FLCNUDENN FLCN/SMCR8-type domain-containing protein. (579 aa)
LOC102448206Dimer_Tnp_hAT domain-containing protein. (688 aa)
ARL2Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (205 aa)
PRXL2CPeroxiredoxin like 2C. (195 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
MTORSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2522 aa)
IDEInsulin degrading enzyme; Belongs to the peptidase M16 family. (1008 aa)
PRKAA1Non-specific serine/threonine protein kinase. (560 aa)
JMJD8Jumonji domain containing 8. (265 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (390 aa)
PPP1R3AProtein phosphatase 1 regulatory subunit 3A. (1308 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1. (767 aa)
OPN3Opsin 3; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. (273 aa)
IGF2Insulin like growth factor 2. (186 aa)
IFNAR1Interferon alpha and beta receptor subunit 1. (547 aa)
PPARGC1APPARG coactivator 1 alpha. (795 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (440 aa)
TIGARUncharacterized protein. (274 aa)
ETFBKMTUncharacterized protein. (264 aa)
EIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (212 aa)
K7FWM9_PELSIDimer_Tnp_hAT domain-containing protein. (542 aa)
FAM214AFamily with sequence similarity 214 member A. (1041 aa)
AK4Adenylate kinase 4. (136 aa)
PPP1R3DProtein phosphatase 1 regulatory subunit 3D. (285 aa)
LOC102445473Uncharacterized protein. (558 aa)
LOC102451702Protein phosphatase 1 regulatory subunit. (303 aa)
K7F011_PELSIUncharacterized protein. (35 aa)
K7F0C8_PELSIDUF4371 domain-containing protein. (613 aa)
K7F0I9_PELSIUncharacterized protein. (573 aa)
K7F0L6_PELSIDUF4371 domain-containing protein. (617 aa)
PPP1R3BProtein phosphatase 1 regulatory subunit. (284 aa)
K7F1W5_PELSIDUF4371 domain-containing protein. (591 aa)
K7F1Z8_PELSIDUF4371 domain-containing protein. (532 aa)
ZBTB20Zinc finger and BTB domain containing 20. (390 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (964 aa)
NOA1Nitric oxide associated 1. (497 aa)
PRDM16PR/SET domain 16. (1155 aa)
TACO1Translational activator of cytochrome c oxidase I. (214 aa)
K7FA62_PELSIUncharacterized protein. (123 aa)
K7FAK1_PELSIParathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. (93 aa)
EP300E1A binding protein p300. (2399 aa)
MECOM-2Uncharacterized protein. (126 aa)
PDE12Phosphodiesterase 12. (615 aa)
NDUFA4NDUFA4 mitochondrial complex associated. (82 aa)
PINK1PTEN induced kinase 1. (364 aa)
TRAP1TNF receptor associated protein 1. (707 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
COX7A2Cytochrome c oxidase subunit 7A2. (59 aa)
HTR2A5-hydroxytryptamine receptor 2A. (468 aa)
DNAJC15DnaJ heat shock protein family (Hsp40) member C15. (110 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (566 aa)
SIRT6Sirtuin 6. (341 aa)
COX7A2LCytochrome c oxidase subunit 7A2 like. (116 aa)
COA8Cytochrome c oxidase assembly factor 8. (91 aa)
K7FJ02_PELSIPhosphatidylinositol 3-kinase catalytic subunit type 3. (787 aa)
K7FIQ5_PELSIPI3K-ABD domain-containing protein; Belongs to the PI3/PI4-kinase family. (211 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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