(11 nodes) Thymic T cell selection network (Pelodiscus sinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (276 aa)
	CCR7	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (377 aa)
	GLI3	GLI family zinc finger 3. (1575 aa)
	CD74	CD74 molecule. (293 aa)
	GATA3	GATA binding protein 3. (425 aa)
	CD3E	Uncharacterized protein. (152 aa)
	PTPRC	Protein tyrosine phosphatase receptor type C. (736 aa)
	CARD11	Caspase recruitment domain family member 11. (1164 aa)
	STK11	Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (373 aa)
	ZAP70	Tyrosine-protein kinase. (614 aa)
	JAG2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1262 aa)

Your Current Organism:

Pelodiscus sinensis

NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CARD11	ZAP70	ENSPSIP00000008043	ENSPSIP00000005265	Caspase recruitment domain family member 11.	Tyrosine-protein kinase.	0.490
CCR7	CD3E	ENSPSIP00000002562	ENSPSIP00000013345	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.450
CCR7	PTPRC	ENSPSIP00000002562	ENSPSIP00000008230	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	Protein tyrosine phosphatase receptor type C.	0.514
CD3E	CCR7	ENSPSIP00000013345	ENSPSIP00000002562	Uncharacterized protein.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.450
CD3E	PTPRC	ENSPSIP00000013345	ENSPSIP00000008230	Uncharacterized protein.	Protein tyrosine phosphatase receptor type C.	0.760
CD3E	ZAP70	ENSPSIP00000013345	ENSPSIP00000005265	Uncharacterized protein.	Tyrosine-protein kinase.	0.975
PTPRC	CCR7	ENSPSIP00000008230	ENSPSIP00000002562	Protein tyrosine phosphatase receptor type C.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.514
PTPRC	CD3E	ENSPSIP00000008230	ENSPSIP00000013345	Protein tyrosine phosphatase receptor type C.	Uncharacterized protein.	0.760
PTPRC	ZAP70	ENSPSIP00000008230	ENSPSIP00000005265	Protein tyrosine phosphatase receptor type C.	Tyrosine-protein kinase.	0.491
ZAP70	CARD11	ENSPSIP00000005265	ENSPSIP00000008043	Tyrosine-protein kinase.	Caspase recruitment domain family member 11.	0.490
ZAP70	CD3E	ENSPSIP00000005265	ENSPSIP00000013345	Tyrosine-protein kinase.	Uncharacterized protein.	0.975
ZAP70	PTPRC	ENSPSIP00000005265	ENSPSIP00000008230	Tyrosine-protein kinase.	Protein tyrosine phosphatase receptor type C.	0.491