STRINGSTRING
TNR TNR TLR2 TLR2 ORAI1 ORAI1 ARC ARC CBL CBL TLR6 TLR6 UNC5B UNC5B CLN6 CLN6 PTPRC PTPRC CAVIN2 CAVIN2 ARID3C ARID3C ASAH2 ASAH2 MAL2 MAL2 TEK TEK SLC2A4 SLC2A4 PODXL PODXL CLIP3 CLIP3 K7FYF9_PELSI K7FYF9_PELSI MILR1 MILR1 K7FXZ1_PELSI K7FXZ1_PELSI THY1 THY1 NPHS2 NPHS2 LRRK2 LRRK2 RIPK1 RIPK1 CAVIN4 CAVIN4 TRPC5 TRPC5 K7FUC9_PELSI K7FUC9_PELSI RFTN1 RFTN1 BAALC BAALC TNFRSF1B TNFRSF1B LCP2 LCP2 CARD11 CARD11 ADGRG1 ADGRG1 K7FHL0_PELSI K7FHL0_PELSI LOC102449905 LOC102449905 HTR2A HTR2A SMO SMO LOC102450134 LOC102450134 SKAP1 SKAP1 TGFBR2 TGFBR2 VDAC1 VDAC1 TNF TNF DPP4 DPP4 CAVIN1 CAVIN1 AKAP6 AKAP6 K7GDF5_PELSI K7GDF5_PELSI PLLP PLLP ADRA1A ADRA1A ADTRP ADTRP KIF18A KIF18A PIKFYVE PIKFYVE STOML3 STOML3 SLC9A1 SLC9A1 HCK HCK FYB2 FYB2 PLPP3 PLPP3 LOC102457599 LOC102457599 PLPP2 PLPP2 BSG BSG EMP2 EMP2 SCARB1 SCARB1 LOC102459935 LOC102459935 ADCY1 ADCY1 BVES BVES LAMTOR1 LAMTOR1 SMPD2 SMPD2 AQP1 AQP1 LOC102462623 LOC102462623 K7G565_PELSI K7G565_PELSI ADAM17 ADAM17 MAG MAG K7G6E9_PELSI K7G6E9_PELSI KDR KDR ATP2B4 ATP2B4 ADD2 ADD2 SLC1A2 SLC1A2 NFAM1 NFAM1 LYPD6 LYPD6 P2RX7 P2RX7 NEU3 NEU3 STIM1 STIM1 LAMTOR3 LAMTOR3 CD4 CD4 SYNJ2 SYNJ2 STOM STOM PPT1 PPT1 ADCYAP1R1 ADCYAP1R1 CAV2 CAV2 LYN LYN MALL MALL MLC1 MLC1 CBLB CBLB PLPP1 PLPP1 K7GCF0_PELSI K7GCF0_PELSI LAMTOR4 LAMTOR4 K7GCN5_PELSI K7GCN5_PELSI HPSE HPSE CXADR CXADR PSEN2 PSEN2 P2RX1 P2RX1 PECAM1 PECAM1 K7GII3_PELSI K7GII3_PELSI SULF1 SULF1 IL6ST IL6ST CAV3 CAV3 EZR EZR TGFBR1 TGFBR1 LAMTOR5 LAMTOR5 CD36 CD36 LCK LCK PAG1 PAG1 PARK7 PARK7 SLC2A1 SLC2A1 P2RX3 P2RX3 LRP6 LRP6 TPP1 TPP1 KCNQ1 KCNQ1 TFPI TFPI PTCH1 PTCH1 SLC6A4 SLC6A4 SERPINH1 SERPINH1 KCNE3 KCNE3 ADCY8 ADCY8 FLOT2 FLOT2 DLL1 DLL1 RGS19 RGS19 AQP5 AQP5 RET RET FAS FAS PDPN PDPN IKBKB IKBKB PSEN1 PSEN1 TRPC4 TRPC4 DAG1 DAG1 K7F2T9_PELSI K7F2T9_PELSI STOML2 STOML2 CTNNB1 CTNNB1 FXYD1 FXYD1 INPP5D INPP5D MYADM MYADM KCNE1 KCNE1 LOC102445500 LOC102445500 RTN4RL1 RTN4RL1 AKAP5 AKAP5 LOC102457570 LOC102457570
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TNRTenascin R. (1562 aa)
TLR2TIR domain-containing protein; Belongs to the Toll-like receptor family. (783 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (185 aa)
ARCActivity regulated cytoskeleton associated protein. (405 aa)
CBLCbl proto-oncogene. (542 aa)
TLR6Toll-like receptor. (653 aa)
UNC5BUnc-5 netrin receptor B. (944 aa)
CLN6CLN6 transmembrane ER protein. (252 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (736 aa)
CAVIN2Caveolae associated protein 2. (411 aa)
ARID3CAT-rich interaction domain 3C. (268 aa)
ASAH2Neutral ceramidase. (730 aa)
MAL2Mal, T cell differentiation protein 2 (gene/pseudogene). (139 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
PODXLPodocalyxin like. (535 aa)
CLIP3CAP-Gly domain containing linker protein 3. (532 aa)
K7FYF9_PELSIIon_trans domain-containing protein; Belongs to the potassium channel family. (300 aa)
MILR1Uncharacterized protein. (242 aa)
K7FXZ1_PELSIKCNQ_channel domain-containing protein. (99 aa)
THY1Thy-1 cell surface antigen. (182 aa)
NPHS2NPHS2 stomatin family member, podocin. (389 aa)
LRRK2Leucine rich repeat kinase 2. (2537 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (716 aa)
CAVIN4Caveolae associated protein 4. (354 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (989 aa)
K7FUC9_PELSIUncharacterized protein. (313 aa)
RFTN1Raftlin, lipid raft linker 1. (611 aa)
BAALCBAALC binder of MAP3K1 and KLF4. (93 aa)
TNFRSF1BTNF receptor superfamily member 1B. (476 aa)
LCP2Lymphocyte cytosolic protein 2. (534 aa)
CARD11Caspase recruitment domain family member 11. (1164 aa)
ADGRG1Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (687 aa)
K7FHL0_PELSIG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (270 aa)
LOC102449905Fibrinogen C-terminal domain-containing protein. (330 aa)
HTR2A5-hydroxytryptamine receptor 2A. (468 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (677 aa)
LOC102450134Fibrinogen C-terminal domain-containing protein. (330 aa)
SKAP1Src kinase associated phosphoprotein 1. (264 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (584 aa)
VDAC1Voltage dependent anion channel 1. (283 aa)
TNFTumor necrosis factor. (229 aa)
DPP4Uncharacterized protein; Belongs to the peptidase S9B family. (760 aa)
CAVIN1Caveolae associated protein 1. (358 aa)
AKAP6A-kinase anchoring protein 6. (2314 aa)
K7GDF5_PELSITransporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (547 aa)
PLLPPlasmolipin. (137 aa)
ADRA1AAdrenoceptor alpha 1A. (467 aa)
ADTRPAndrogen dependent TFPI regulating protein. (233 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (933 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (1498 aa)
STOML3Stomatin like 3. (208 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (773 aa)
HCKHCK proto-oncogene, Src family tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. (451 aa)
FYB2FYN binding protein 2. (723 aa)
PLPP3acidPPc domain-containing protein. (312 aa)
LOC102457599TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
PLPP2Phospholipid phosphatase 2. (221 aa)
BSGBasigin (Ok blood group). (374 aa)
EMP2Epithelial membrane protein 2. (166 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (454 aa)
LOC102459935Pro-kuma_activ domain-containing protein. (311 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1090 aa)
BVESBlood vessel epicardial substance. (616 aa)
LAMTOR1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (163 aa)
SMPD2Sphingomyelin phosphodiesterase 2. (374 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
LOC102462623ABC transporter domain-containing protein. (621 aa)
K7G565_PELSIABC2_membrane domain-containing protein. (376 aa)
ADAM17ADAM metallopeptidase domain 17. (836 aa)
MAGMyelin associated glycoprotein. (617 aa)
K7G6E9_PELSIABC transporter domain-containing protein. (661 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1328 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1215 aa)
ADD2Adducin 2. (735 aa)
SLC1A2Amino acid transporter. (569 aa)
NFAM1NFAT activating protein with ITAM motif 1. (292 aa)
LYPD6LY6/PLAUR domain containing 6. (169 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (566 aa)
NEU3Neuraminidase 3. (428 aa)
STIM1Stromal interaction molecule 1. (683 aa)
LAMTOR3Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3. (124 aa)
CD4Ig-like domain-containing protein. (458 aa)
SYNJ2Synaptojanin 2. (1469 aa)
STOMStomatin. (232 aa)
PPT1Palmitoyl-protein thioesterase 1. (267 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (473 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (158 aa)
LYNTyrosine-protein kinase. (517 aa)
MALLMal, T cell differentiation protein like. (158 aa)
MLC1Modulator of VRAC current 1. (379 aa)
CBLBCbl proto-oncogene B. (1031 aa)
PLPP1Phospholipid phosphatase 1. (222 aa)
K7GCF0_PELSIFlotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (423 aa)
LAMTOR4Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4. (98 aa)
K7GCN5_PELSIUncharacterized protein. (164 aa)
HPSEHeparanase. (482 aa)
CXADRUncharacterized protein. (368 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (387 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (402 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (689 aa)
K7GII3_PELSIUncharacterized protein. (768 aa)
SULF1Extracellular sulfatase. (869 aa)
IL6STInterleukin 6 signal transducer. (922 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (152 aa)
EZREzrin. (600 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
LAMTOR5Late endosomal/lysosomal adaptor, MAPK and MTOR activator 5. (79 aa)
CD36CD36 molecule; Belongs to the CD36 family. (479 aa)
LCKTyrosine-protein kinase. (516 aa)
PAG1Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (429 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
SLC2A1Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (480 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (396 aa)
LRP6LDL receptor related protein 6. (1461 aa)
TPP1Peptidase S53 domain-containing protein. (279 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (374 aa)
TFPITissue factor pathway inhibitor. (302 aa)
PTCH1Patched 1. (1442 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (669 aa)
SERPINH1Serpin family H member 1; Belongs to the serpin family. (405 aa)
KCNE3Potassium voltage-gated channel subfamily E regulatory subunit 3. (117 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1070 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (256 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (726 aa)
RGS19Regulator of G protein signaling 19. (221 aa)
AQP5Aquaporin 5; Belongs to the MIP/aquaporin (TC 1.A.8) family. (265 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1103 aa)
FASFas cell surface death receptor. (303 aa)
PDPNUncharacterized protein. (145 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (714 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa)
TRPC4Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (976 aa)
DAG1Dystroglycan 1. (896 aa)
K7F2T9_PELSIABC transporter domain-containing protein. (663 aa)
STOML2Stomatin like 2. (359 aa)
CTNNB1Uncharacterized protein. (778 aa)
FXYD1FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (92 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1213 aa)
MYADMMyeloid associated differentiation marker. (313 aa)
KCNE1Uncharacterized protein. (126 aa)
LOC102445500Uncharacterized protein. (283 aa)
RTN4RL1Reticulon 4 receptor like 1. (423 aa)
AKAP5A-kinase anchoring protein 5. (487 aa)
LOC102457570TIR domain-containing protein; Belongs to the Toll-like receptor family. (783 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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