STRINGSTRING
CDC6 CDC6 DHX9 DHX9 FBRS FBRS LOC102458614 LOC102458614 ESR1 ESR1 FOSL2 FOSL2 WNT2B WNT2B LIF LIF CD248 CD248 WNT1 WNT1 LIG4 LIG4 JUN JUN WNT2 WNT2 CDK4 CDK4 FN1 FN1 DDR2 DDR2 CTC1 CTC1 AQP1 AQP1 CD74 CD74 PDGFB PDGFB K7FY56_PELSI K7FY56_PELSI FNDC3B FNDC3B K7FIC0_PELSI K7FIC0_PELSI MYC MYC EREG EREG SIRT6 SIRT6 CDK6 CDK6 PDGFC PDGFC WAPL WAPL K7FQ62_PELSI K7FQ62_PELSI GAS6 GAS6 NDUFS4 NDUFS4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (548 aa)
DHX9DExH-box helicase 9. (1267 aa)
FBRSFibrosin. (530 aa)
LOC102458614Uncharacterized protein. (824 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (588 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (323 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (334 aa)
LIFLIF interleukin 6 family cytokine. (141 aa)
CD248CD248 molecule. (634 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (372 aa)
LIG4DNA ligase. (912 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (314 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
CDK4Cyclin dependent kinase 4. (216 aa)
FN1Fibronectin 1. (2389 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (887 aa)
CTC1Uncharacterized protein. (1296 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa)
CD74CD74 molecule. (293 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (245 aa)
K7FY56_PELSIUncharacterized protein. (164 aa)
FNDC3BFibronectin type III domain containing 3B. (1211 aa)
K7FIC0_PELSIIntegrin beta; Belongs to the integrin beta chain family. (739 aa)
MYCMYC proto-oncogene, bHLH transcription factor. (324 aa)
EREGEpiregulin. (154 aa)
SIRT6Sirtuin 6. (341 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
PDGFCPlatelet derived growth factor C. (345 aa)
WAPLWAPL cohesin release factor. (1199 aa)
K7FQ62_PELSIUncharacterized protein. (809 aa)
GAS6Growth arrest specific 6. (403 aa)
NDUFS4NADH:ubiquinone oxidoreductase subunit S4. (156 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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