STRINGSTRING
PRLH PRLH SEMA6C SEMA6C TNKS2 TNKS2 WNT2 WNT2 PLAC8 PLAC8 AKAP6 AKAP6 K7GEC4_PELSI K7GEC4_PELSI LOC112544914 LOC112544914 DIP2B DIP2B K7GDF5_PELSI K7GDF5_PELSI FN1 FN1 TBX20 TBX20 LOC102448275 LOC102448275 STAT3 STAT3 ADRB1 ADRB1 MYCBP2 MYCBP2 ULK2 ULK2 MFSD2A MFSD2A MYOZ1 MYOZ1 K7GA90_PELSI K7GA90_PELSI BCL2L11 BCL2L11 ADNP ADNP LOC102450523 LOC102450523 BMPR2 BMPR2 MAG MAG MAPK11 MAPK11 ADRB3 ADRB3 WWC1 WWC1 SGPL1 SGPL1 SEMA4A SEMA4A DUSP10 DUSP10 SEMA4D SEMA4D PIK3CA PIK3CA FXN FXN NKX2-5 NKX2-5 GHRHR GHRHR CRABP2 CRABP2 ZFYVE27 ZFYVE27 K7FJ02_PELSI K7FJ02_PELSI JARID2 JARID2 MBD5 MBD5 MKKS MKKS CYFIP1 CYFIP1 K7FIQ5_PELSI K7FIQ5_PELSI SYT2 SYT2 LATS2 LATS2 SMO SMO K7FHL0_PELSI K7FHL0_PELSI PEX5 PEX5 SEMA5A SEMA5A MAPK14 MAPK14 K7FGV8_PELSI K7FGV8_PELSI SEMA7A SEMA7A SMAD7 SMAD7 ITSN2 ITSN2 PPARD PPARD RAI1 RAI1 K7FDM1_PELSI K7FDM1_PELSI PRKN PRKN CTDP1 CTDP1 CREB1 CREB1 DISC1 DISC1 MUL1 MUL1 OSTN OSTN RND2 RND2 SAV1 SAV1 HTRA2 HTRA2 SEMA5B SEMA5B KCNK2 KCNK2 ZFPM2 ZFPM2 EDN1 EDN1 GPAT4 GPAT4 WNT3 WNT3 SYT17 SYT17 TP73 TP73 SASH3 SASH3 K7F890_PELSI K7F890_PELSI TOMM70 TOMM70 IL7 IL7 WNT2B WNT2B BCL2 BCL2 HOPX HOPX GDF11 GDF11 GAMT GAMT SPART SPART PI16 PI16 RAG2 RAG2 NGF NGF BDNF BDNF LOC106732081 LOC106732081 FGF13 FGF13 IFRD1 IFRD1 G6PD G6PD VGLL4 VGLL4 NOL12 NOL12 GOLGA4 GOLGA4 SYT4 SYT4 NIPBL NIPBL IGF2 IGF2 TNR TNR RUFY3 RUFY3 CDKL5 CDKL5 K7G2N3_PELSI K7G2N3_PELSI MSTN MSTN K7G3B3_PELSI K7G3B3_PELSI AGRN AGRN HLX HLX STK4 STK4 BCL11A BCL11A BBS2 BBS2 TGFBR1 TGFBR1 TRPV2 TRPV2 SEMA3C SEMA3C COLQ COLQ EZR EZR SEMA6A SEMA6A SEMA6D SEMA6D PLS1 PLS1 SEMA3E SEMA3E ARX ARX SEMA3A SEMA3A SEMA3D SEMA3D BBS4 BBS4 IST1 IST1 LATS1 LATS1 MUSK MUSK ANAPC2 ANAPC2 ISLR ISLR SEMA3G SEMA3G ISLR2 ISLR2 SMURF1 SMURF1 MAP2 MAP2 EFNA5 EFNA5 DBNL DBNL AR AR SEMA4F SEMA4F DRD2 DRD2 DLL1 DLL1 WWC2 WWC2 DRAXIN DRAXIN PPIB PPIB HNF1B HNF1B CSF1 CSF1 YBX3 YBX3 WNT3A WNT3A GPAM GPAM NKD1 NKD1 GSK3B GSK3B GATA6 GATA6 ULK1 ULK1 K7FNR2_PELSI K7FNR2_PELSI TSHR TSHR ADRB2 ADRB2 MAPT MAPT PTCH1 PTCH1 LOC102462376 LOC102462376 SLC6A4 SLC6A4 PLAA PLAA FGF8 FGF8 SEMA6B SEMA6B FTO FTO SYT1 SYT1 LGMN LGMN RYK RYK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRLHProlactin releasing hormone. (87 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (1016 aa)
TNKS2Poly [ADP-ribose] polymerase. (1101 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
PLAC8Uncharacterized protein. (105 aa)
AKAP6A-kinase anchoring protein 6. (2314 aa)
K7GEC4_PELSIUncharacterized protein. (138 aa)
LOC112544914Uncharacterized protein. (112 aa)
DIP2BDisco interacting protein 2 homolog B. (1555 aa)
K7GDF5_PELSITransporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (547 aa)
FN1Fibronectin 1. (2389 aa)
TBX20T-box transcription factor 20. (441 aa)
LOC102448275ZP domain-containing protein. (362 aa)
STAT3Signal transducer and activator of transcription. (707 aa)
ADRB1Adrenoceptor beta 1. (488 aa)
MYCBP2MYC binding protein 2. (3494 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1015 aa)
MFSD2AMajor facilitator superfamily domain containing 2A. (503 aa)
MYOZ1Myozenin 1. (306 aa)
K7GA90_PELSISTAT_int domain-containing protein. (636 aa)
BCL2L11BCL2 like 11. (225 aa)
ADNPActivity dependent neuroprotector homeobox. (1124 aa)
LOC102450523Uncharacterized protein. (181 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1042 aa)
MAGMyelin associated glycoprotein. (617 aa)
MAPK11Mitogen-activated protein kinase. (361 aa)
ADRB3G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (443 aa)
WWC1WW and C2 domain containing 1. (937 aa)
SGPL1Uncharacterized protein. (304 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (769 aa)
DUSP10Dual specificity phosphatase 10. (480 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (857 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1029 aa)
FXNFrataxin. (159 aa)
NKX2-5NK2 homeobox 5. (272 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (261 aa)
CRABP2Cellular retinoic acid-binding protein 1; Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors. (138 aa)
ZFYVE27Zinc finger FYVE-type containing 27. (268 aa)
K7FJ02_PELSIPhosphatidylinositol 3-kinase catalytic subunit type 3. (787 aa)
JARID2Jumonji and AT-rich interaction domain containing 2. (1232 aa)
MBD5Methyl-CpG binding domain protein 5. (959 aa)
MKKSMcKusick-Kaufman syndrome. (572 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
K7FIQ5_PELSIPI3K-ABD domain-containing protein; Belongs to the PI3/PI4-kinase family. (211 aa)
SYT2Uncharacterized protein. (436 aa)
LATS2Non-specific serine/threonine protein kinase. (1125 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (677 aa)
K7FHL0_PELSIG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (270 aa)
PEX5Peroxisomal biogenesis factor 5. (559 aa)
SEMA5ASemaphorin 5A. (1144 aa)
MAPK14Mitogen-activated protein kinase. (321 aa)
K7FGV8_PELSIProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (336 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (618 aa)
SMAD7Mothers against decapentaplegic homolog. (387 aa)
ITSN2Intersectin 2. (1694 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
RAI1Retinoic acid induced 1. (1898 aa)
K7FDM1_PELSIUncharacterized protein. (254 aa)
PRKNRBR-type E3 ubiquitin transferase. (119 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (759 aa)
CREB1cAMP responsive element binding protein 1. (327 aa)
DISC1DISC1 scaffold protein. (635 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (352 aa)
OSTNOsteocrin. (134 aa)
RND2Rho family GTPase 2. (211 aa)
SAV1Salvador family WW domain containing protein 1. (313 aa)
HTRA2HtrA serine peptidase 2. (322 aa)
SEMA5BSemaphorin 5B. (1092 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (410 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1004 aa)
EDN1Endothelin 1. (204 aa)
GPAT4Glycerol-3-phosphate acyltransferase 4. (455 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (356 aa)
SYT17Synaptotagmin 17. (375 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (633 aa)
SASH3SAM domain-containing protein. (126 aa)
K7F890_PELSIPeptidase_M23 domain-containing protein. (144 aa)
TOMM70Translocase of outer mitochondrial membrane 70. (501 aa)
IL7Uncharacterized protein. (144 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (334 aa)
BCL2BCL2 apoptosis regulator. (232 aa)
HOPXHOP homeobox. (73 aa)
GDF11Growth differentiation factor 11. (229 aa)
GAMTGuanidinoacetate N-methyltransferase. (237 aa)
SPARTSpartin. (630 aa)
PI16SCP domain-containing protein; Belongs to the CRISP family. (466 aa)
RAG2Recombination activating 2. (533 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (242 aa)
BDNFBrain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (246 aa)
LOC106732081Protein kinase domain-containing protein. (174 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (193 aa)
IFRD1Interferon related developmental regulator 1. (460 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (513 aa)
VGLL4Vestigial like family member 4. (295 aa)
NOL12Uncharacterized protein. (215 aa)
GOLGA4Golgin A4. (2233 aa)
SYT4Synaptotagmin 4. (425 aa)
NIPBLNipped-B protein. (2788 aa)
IGF2Insulin like growth factor 2. (186 aa)
TNRTenascin R. (1562 aa)
RUFY3RUN and FYVE domain containing 3. (635 aa)
CDKL5Cyclin dependent kinase like 5. (644 aa)
K7G2N3_PELSIC2 domain-containing protein. (121 aa)
MSTNMyostatin. (375 aa)
K7G3B3_PELSIUncharacterized protein. (206 aa)
AGRNAgrin. (1903 aa)
HLXH2.0 like homeobox. (354 aa)
STK4Serine/threonine kinase 4. (486 aa)
BCL11ABAF chromatin remodeling complex subunit BCL11A. (796 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (683 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (733 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (750 aa)
COLQCollagen like tail subunit of asymmetric acetylcholinesterase. (456 aa)
EZREzrin. (600 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1027 aa)
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1078 aa)
PLS1Plastin 1. (630 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (757 aa)
ARXAristaless related homeobox. (539 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (809 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (774 aa)
BBS4Bardet-Biedl syndrome 4. (519 aa)
IST1IST1 factor associated with ESCRT-III. (378 aa)
LATS1Large tumor suppressor kinase 1. (970 aa)
MUSKMuscle associated receptor tyrosine kinase. (969 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (771 aa)
ISLRImmunoglobulin superfamily containing leucine rich repeat. (339 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (753 aa)
ISLR2Immunoglobulin superfamily containing leucine rich repeat 2. (551 aa)
SMURF1SMAD specific E3 ubiquitin protein ligase 1. (556 aa)
MAP2Microtubule-associated protein. (1868 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (191 aa)
DBNLDrebrin like. (411 aa)
ARAndrogen receptor. (721 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (718 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (446 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (726 aa)
WWC2WW and C2 domain containing 2. (1203 aa)
DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord; Belongs to the draxin family. (343 aa)
PPIBPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (171 aa)
HNF1BHNF1 homeobox B. (559 aa)
CSF1Uncharacterized protein. (649 aa)
YBX3Y-box binding protein 3. (214 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (241 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (813 aa)
NKD1NKD inhibitor of WNT signaling pathway 1. (437 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (419 aa)
GATA6GATA binding protein 6. (514 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1030 aa)
K7FNR2_PELSIUncharacterized protein; Belongs to the semaphorin family. (557 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (742 aa)
ADRB2Adrenoceptor beta 2. (367 aa)
MAPTMicrotubule-associated protein. (736 aa)
PTCH1Patched 1. (1442 aa)
LOC102462376Uncharacterized protein; Belongs to the semaphorin family. (720 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (669 aa)
PLAAPhospholipase A2 activating protein. (739 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
SEMA6BSemaphorin 6B; Belongs to the semaphorin family. (383 aa)
FTOFTO alpha-ketoglutarate dependent dioxygenase. (509 aa)
SYT1Synaptotagmin 1. (424 aa)
LGMNLegumain. (411 aa)
RYKReceptor like tyrosine kinase. (541 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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