STRINGSTRING
NRG1 NRG1 GHRL GHRL CLCF1 CLCF1 IL12B IL12B VTN VTN IL6ST IL6ST PECAM1 PECAM1 NOX4 NOX4 GREM1 GREM1 FBXW7 FBXW7 AGT AGT IL15 IL15 IL18 IL18 SH2D1B SH2D1B IFNG IFNG PTPN1 PTPN1 ARL2BP ARL2BP ADRA1A ADRA1A ENPP2 ENPP2 LYN LYN ADNP ADNP ERCC6 ERCC6 LTK LTK ALKAL1 ALKAL1 HBEGF HBEGF DOK7 DOK7 ANGPT1 ANGPT1 NRG2 NRG2 CSPG4 CSPG4 SEMA4D SEMA4D LRRK1 LRRK1 ABI1 ABI1 VEGFA VEGFA ADAM17 ADAM17 CD74 CD74 TP53 TP53 CSF1R CSF1R TGFA TGFA IGF2 IGF2 SYK SYK CASS4 CASS4 PDGFB PDGFB NCF1 NCF1 MILR1 MILR1 CSF3 CSF3 CRLF1 CRLF1 NRP1 NRP1 EFNA5 EFNA5 ALK ALK RICTOR RICTOR BANK1 BANK1 ITGA5 ITGA5 FGFR3 FGFR3 IL6 IL6 FBXW9 FBXW9 ALK-2 ALK-2 RIPK2 RIPK2 K7FRK0_PELSI K7FRK0_PELSI FGF7 FGF7 GAS6 GAS6 DGKQ DGKQ EPGN EPGN EREG EREG AREG AREG K7FN03_PELSI K7FN03_PELSI BTC BTC MLST8 MLST8 LOC102462376 LOC102462376 KIT KIT FGF8 FGF8 PTPRC PTPRC MTOR MTOR K7FIC0_PELSI K7FIC0_PELSI HTR2A HTR2A LOC102462652 LOC102462652 ARHGEF2 ARHGEF2 PAK2 PAK2 CTF1 CTF1 K7FE02_PELSI K7FE02_PELSI CNTF CNTF BMP6 BMP6 NEURL1 NEURL1 NEDD9 NEDD9 HES5 HES5 PIBF1 PIBF1 K7F7G4_PELSI K7F7G4_PELSI K7F7A9_PELSI K7F7A9_PELSI RELN RELN PLPP3 PLPP3 K7F6U7_PELSI K7F6U7_PELSI IL20 IL20 PARP14 PARP14 PARP9 PARP9 LIF LIF STAP1 STAP1 ALKAL2 ALKAL2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NRG1Neuregulin 1. (533 aa)
GHRLGhrelin and obestatin prepropeptide. (118 aa)
CLCF1Cardiotrophin like cytokine factor 1. (232 aa)
IL12BInterleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (321 aa)
VTNSMB domain-containing protein. (455 aa)
IL6STInterleukin 6 signal transducer. (922 aa)
PECAM1Platelet and endothelial cell adhesion molecule 1. (689 aa)
NOX4NADPH oxidase 4. (459 aa)
GREM1Gremlin. (182 aa)
FBXW7F-box and WD repeat domain containing 7. (610 aa)
AGTAngiotensinogen; Belongs to the serpin family. (476 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (172 aa)
IL18Interleukin 18. (200 aa)
SH2D1BSH2 domain-containing protein. (185 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (168 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (359 aa)
ARL2BPADP ribosylation factor like GTPase 2 binding protein. (162 aa)
ADRA1AAdrenoceptor alpha 1A. (467 aa)
ENPP2Ectonucleotide pyrophosphatase/phosphodiesterase 2. (860 aa)
LYNTyrosine-protein kinase. (517 aa)
ADNPActivity dependent neuroprotector homeobox. (1124 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1273 aa)
LTKTyrosine-protein kinase receptor. (1183 aa)
ALKAL1ALK and LTK ligand 1. (148 aa)
HBEGFHeparin binding EGF like growth factor. (139 aa)
DOK7Docking protein 7. (511 aa)
ANGPT1Angiopoietin 1. (409 aa)
NRG2Neuregulin 2. (494 aa)
CSPG4Chondroitin sulfate proteoglycan 4. (2265 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (857 aa)
LRRK1Leucine rich repeat kinase 1. (1796 aa)
ABI1Abl interactor 1. (476 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (217 aa)
ADAM17ADAM metallopeptidase domain 17. (836 aa)
CD74CD74 molecule. (293 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (390 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (962 aa)
TGFATransforming growth factor alpha. (162 aa)
IGF2Insulin like growth factor 2. (186 aa)
SYKTyrosine-protein kinase. (445 aa)
CASS4Cas scaffold protein family member 4. (846 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (245 aa)
NCF1Neutrophil cytosolic factor 1. (390 aa)
MILR1Uncharacterized protein. (242 aa)
CSF3Colony stimulating factor 3. (200 aa)
CRLF1Cytokine receptor like factor 1. (310 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (916 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (191 aa)
ALKTyrosine-protein kinase receptor. (813 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1715 aa)
BANK1B cell scaffold protein with ankyrin repeats 1. (654 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (995 aa)
FGFR3Fibroblast growth factor receptor. (827 aa)
IL6Interleukin 6. (211 aa)
FBXW9F-box and WD repeat domain containing 9. (462 aa)
ALK-2Uncharacterized protein. (386 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (562 aa)
K7FRK0_PELSIUncharacterized protein. (622 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
GAS6Growth arrest specific 6. (403 aa)
DGKQDiacylglycerol kinase. (853 aa)
EPGNEpithelial mitogen. (109 aa)
EREGEpiregulin. (154 aa)
AREGAmphiregulin. (212 aa)
K7FN03_PELSIProtein kinase domain-containing protein. (449 aa)
BTCBetacellulin. (154 aa)
MLST8MTOR associated protein, LST8 homolog. (271 aa)
LOC102462376Uncharacterized protein; Belongs to the semaphorin family. (720 aa)
KITKIT proto-oncogene, receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (947 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (736 aa)
MTORSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2522 aa)
K7FIC0_PELSIIntegrin beta; Belongs to the integrin beta chain family. (739 aa)
HTR2A5-hydroxytryptamine receptor 2A. (468 aa)
LOC102462652Uncharacterized protein. (2300 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (907 aa)
PAK2Non-specific serine/threonine protein kinase. (520 aa)
CTF1Cardiotrophin 1. (129 aa)
K7FE02_PELSIUncharacterized protein. (202 aa)
CNTFCiliary neurotrophic factor. (192 aa)
BMP6Bone morphogenetic protein 6. (284 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (572 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (827 aa)
HES5Hes family bHLH transcription factor 5. (157 aa)
PIBF1Progesterone immunomodulatory binding factor 1. (760 aa)
K7F7G4_PELSIReelin domain-containing protein. (177 aa)
K7F7A9_PELSIUncharacterized protein. (1108 aa)
RELNUncharacterized protein. (2100 aa)
PLPP3acidPPc domain-containing protein. (312 aa)
K7F6U7_PELSIUncharacterized protein. (151 aa)
IL20Interleukin 20. (175 aa)
PARP14Poly [ADP-ribose] polymerase. (1830 aa)
PARP9Uncharacterized protein. (834 aa)
LIFLIF interleukin 6 family cytokine. (141 aa)
STAP1Signal transducing adaptor family member 1. (280 aa)
ALKAL2ALK and LTK ligand 2. (152 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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