STRINGSTRING
PTCD2 PTCD2 DLL4 DLL4 ENG ENG TNNI1 TNNI1 MED1 MED1 EDNRA EDNRA SMAD7 SMAD7 PKP2 PKP2 ZFPM2 ZFPM2 TGFBR1 TGFBR1 NKX2-5 NKX2-5 SMAD4 SMAD4 TNNC1 TNNC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTCD2Pentatricopeptide repeat domain 2. (323 aa)
DLL4Delta like canonical Notch ligand 4. (684 aa)
ENGEndoglin. (652 aa)
TNNI1Troponin I1, slow skeletal type. (188 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1574 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (421 aa)
SMAD7Mothers against decapentaplegic homolog. (387 aa)
PKP2Plakophilin 2. (878 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1004 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
NKX2-5NK2 homeobox 5. (272 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
TNNC1Troponin C1, slow skeletal and cardiac type. (161 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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