STRINGSTRING
PTCH1 PTCH1 ACVR1 ACVR1 BMP7 BMP7 BMP5 BMP5 GATA3 GATA3 EDN1 EDN1 TGFBR1 TGFBR1 ADGRF5 ADGRF5 NKX3-1 NKX3-1 NKX2-5 NKX2-5 BMPR2 BMPR2 EDNRA EDNRA FGF8 FGF8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PTCH1Patched 1. (1442 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (511 aa)
BMP7Bone morphogenetic protein 7. (436 aa)
BMP5Bone morphogenetic protein 5. (439 aa)
GATA3GATA binding protein 3. (425 aa)
EDN1Endothelin 1. (204 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
ADGRF5Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (602 aa)
NKX3-1NK3 homeobox 1. (212 aa)
NKX2-5NK2 homeobox 5. (272 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1042 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (421 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (228 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
Server load: low (24%) [HD]