(17 nodes) Lipoprotein particle receptor binding network (Pelodiscus sinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LRPAP1	LDL receptor related protein associated protein 1. (351 aa)
	PCSK9	Proprotein convertase subtilisin/kexin type 9. (690 aa)
	RELN	Uncharacterized protein. (2100 aa)
	K7F7A9_PELSI	Uncharacterized protein. (1108 aa)
	K7F7G4_PELSI	Reelin domain-containing protein. (177 aa)
	APOA2	Uncharacterized protein. (103 aa)
	CLTCL1	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1670 aa)
	APOB	Apolipoprotein B. (4628 aa)
	LDLRAP1	Low density lipoprotein receptor adaptor protein 1. (179 aa)
	MESD	Mesoderm development LRP chaperone. (172 aa)
	CLTC	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
	HSP90B1	Heat shock protein 90 beta family member 1. (792 aa)
	DAB2	DAB adaptor protein 2. (712 aa)
	APOA5	Apolipoprotein A5. (364 aa)
	LANCL1	LanC like 1. (335 aa)
	DKK1	Dickkopf WNT signaling pathway inhibitor 1. (283 aa)
	ANKRA2	Ankyrin repeat family A member 2. (313 aa)

Your Current Organism:

Pelodiscus sinensis

NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APOA2	APOA5	ENSPSIP00000005294	ENSPSIP00000014942	Uncharacterized protein.	Apolipoprotein A5.	0.693
APOA2	APOB	ENSPSIP00000005294	ENSPSIP00000007565	Uncharacterized protein.	Apolipoprotein B.	0.915
APOA5	APOA2	ENSPSIP00000014942	ENSPSIP00000005294	Apolipoprotein A5.	Uncharacterized protein.	0.693
APOA5	APOB	ENSPSIP00000014942	ENSPSIP00000007565	Apolipoprotein A5.	Apolipoprotein B.	0.802
APOB	APOA2	ENSPSIP00000007565	ENSPSIP00000005294	Apolipoprotein B.	Uncharacterized protein.	0.915
APOB	APOA5	ENSPSIP00000007565	ENSPSIP00000014942	Apolipoprotein B.	Apolipoprotein A5.	0.802
APOB	DAB2	ENSPSIP00000007565	ENSPSIP00000014640	Apolipoprotein B.	DAB adaptor protein 2.	0.604
APOB	HSP90B1	ENSPSIP00000007565	ENSPSIP00000011198	Apolipoprotein B.	Heat shock protein 90 beta family member 1.	0.569
APOB	LDLRAP1	ENSPSIP00000007565	ENSPSIP00000008891	Apolipoprotein B.	Low density lipoprotein receptor adaptor protein 1.	0.743
APOB	PCSK9	ENSPSIP00000007565	ENSPSIP00000003667	Apolipoprotein B.	Proprotein convertase subtilisin/kexin type 9.	0.672
CLTC	CLTCL1	ENSPSIP00000010241	ENSPSIP00000005552	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.900
CLTC	DAB2	ENSPSIP00000010241	ENSPSIP00000014640	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	DAB adaptor protein 2.	0.613
CLTC	LDLRAP1	ENSPSIP00000010241	ENSPSIP00000008891	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Low density lipoprotein receptor adaptor protein 1.	0.515
CLTC	PCSK9	ENSPSIP00000010241	ENSPSIP00000003667	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Proprotein convertase subtilisin/kexin type 9.	0.492
CLTCL1	CLTC	ENSPSIP00000005552	ENSPSIP00000010241	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.900
CLTCL1	DAB2	ENSPSIP00000005552	ENSPSIP00000014640	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	DAB adaptor protein 2.	0.613
CLTCL1	LDLRAP1	ENSPSIP00000005552	ENSPSIP00000008891	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Low density lipoprotein receptor adaptor protein 1.	0.515
CLTCL1	PCSK9	ENSPSIP00000005552	ENSPSIP00000003667	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Proprotein convertase subtilisin/kexin type 9.	0.492
DAB2	APOB	ENSPSIP00000014640	ENSPSIP00000007565	DAB adaptor protein 2.	Apolipoprotein B.	0.604
DAB2	CLTC	ENSPSIP00000014640	ENSPSIP00000010241	DAB adaptor protein 2.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.613