(47 nodes) Response to interleukin-1 network (Pelodiscus sinensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AKAP12	A-kinase anchoring protein 12. (1106 aa)
	K7EZ94_PELSI	Uncharacterized protein. (110 aa)
	LOC102457828	SCY domain-containing protein. (93 aa)
	TANK	TRAF family member associated NFKB activator. (427 aa)
	LOC102458236	SCY domain-containing protein. (449 aa)
	CCL20	C-C motif chemokine. (100 aa)
	LOC102463217	C-C motif chemokine. (91 aa)
	IKBKB	Inhibitor of nuclear factor kappa B kinase subunit beta. (714 aa)
	LOC102463449	C-C motif chemokine. (93 aa)
	CCL5	C-C motif chemokine ligand 5. (90 aa)
	LOC102463959	SCY domain-containing protein. (63 aa)
	LOC102443642	C-C motif chemokine. (91 aa)
	ADAMTS7	ADAM metallopeptidase with thrombospondin type 1 motif 7. (1596 aa)
	K7FGU4_PELSI	Uncharacterized protein. (196 aa)
	MAPK13	Mitogen-activated protein kinase. (365 aa)
	IRAK2	Interleukin 1 receptor associated kinase 2. (705 aa)
	ANXA1	Annexin. (342 aa)
	K7FK04_PELSI	Uncharacterized protein. (171 aa)
	TNFRSF11A	TNF receptor superfamily member 11a. (599 aa)
	MYD88	MYD88 innate immune signal transduction adaptor. (186 aa)
	K7FN03_PELSI	Protein kinase domain-containing protein. (449 aa)
	RPS6KA5	Ribosomal protein S6 kinase. (833 aa)
	CXCL8	Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (104 aa)
	LOC102454632	Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (104 aa)
	CXCL8-2	Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (103 aa)
	K7FQ12_PELSI	Interleukin-1. (182 aa)
	ZC3H12A	Zinc finger CCCH-type containing 12A. (573 aa)
	UPF1	UPF1 RNA helicase and ATPase. (758 aa)
	RIPK2	Receptor interacting serine/threonine kinase 2. (562 aa)
	TRIM63	Tripartite motif containing 63. (394 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (547 aa)
	ST18	ST18 C2H2C-type zinc finger transcription factor. (1056 aa)
	GCLC	Glutamate-cysteine ligase catalytic subunit. (537 aa)
	ANKRD1	Ankyrin repeat domain 1. (319 aa)
	ACOD1	Aconitate decarboxylase 1. (469 aa)
	LOC102459066	Uncharacterized protein. (196 aa)
	YTHDC2	YTH domain containing 2. (1367 aa)
	ADAMTS12	ADAM metallopeptidase with thrombospondin type 1 motif 12. (1569 aa)
	RC3H1	Ring finger and CCCH-type domains 1. (1127 aa)
	USP10	Ubiquitin specific peptidase 10; Belongs to the peptidase C19 family. (531 aa)
	MAP2K7	Mitogen-activated protein kinase kinase 7. (396 aa)
	K7GFU7_PELSI	Uncharacterized protein. (555 aa)
	LOC102463419	Uncharacterized protein. (547 aa)
	LOC102463929	Uncharacterized protein. (436 aa)
	NKX3-1	NK3 homeobox 1. (212 aa)
	PCSK1	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (748 aa)
	RPS6KA4	Ribosomal protein S6 kinase. (752 aa)

Your Current Organism:

Pelodiscus sinensis

NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCL20	CCL5	ENSPSIP00000005215	ENSPSIP00000005808	C-C motif chemokine.	C-C motif chemokine ligand 5.	0.702
CCL20	CXCL8	ENSPSIP00000005215	ENSPSIP00000009779	C-C motif chemokine.	Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family.	0.518
CCL20	CXCL8-2	ENSPSIP00000005215	ENSPSIP00000010034	C-C motif chemokine.	Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family.	0.518
CCL20	K7FK04_PELSI	ENSPSIP00000005215	ENSPSIP00000008364	C-C motif chemokine.	Uncharacterized protein.	0.547
CCL20	K7FQ12_PELSI	ENSPSIP00000005215	ENSPSIP00000010122	C-C motif chemokine.	Interleukin-1.	0.619
CCL20	LOC102443642	ENSPSIP00000005215	ENSPSIP00000006103	C-C motif chemokine.	C-C motif chemokine.	0.483
CCL20	LOC102454632	ENSPSIP00000005215	ENSPSIP00000009796	C-C motif chemokine.	Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family.	0.518
CCL20	LOC102458236	ENSPSIP00000005215	ENSPSIP00000004823	C-C motif chemokine.	SCY domain-containing protein.	0.541
CCL20	LOC102463449	ENSPSIP00000005215	ENSPSIP00000005787	C-C motif chemokine.	C-C motif chemokine.	0.698
CCL20	LOC102463959	ENSPSIP00000005215	ENSPSIP00000005918	C-C motif chemokine.	SCY domain-containing protein.	0.576
CCL5	CCL20	ENSPSIP00000005808	ENSPSIP00000005215	C-C motif chemokine ligand 5.	C-C motif chemokine.	0.702
CCL5	CXCL8	ENSPSIP00000005808	ENSPSIP00000009779	C-C motif chemokine ligand 5.	Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family.	0.578
CCL5	CXCL8-2	ENSPSIP00000005808	ENSPSIP00000010034	C-C motif chemokine ligand 5.	Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family.	0.578
CCL5	K7FK04_PELSI	ENSPSIP00000005808	ENSPSIP00000008364	C-C motif chemokine ligand 5.	Uncharacterized protein.	0.563
CCL5	K7FQ12_PELSI	ENSPSIP00000005808	ENSPSIP00000010122	C-C motif chemokine ligand 5.	Interleukin-1.	0.611
CCL5	LOC102443642	ENSPSIP00000005808	ENSPSIP00000006103	C-C motif chemokine ligand 5.	C-C motif chemokine.	0.649
CCL5	LOC102454632	ENSPSIP00000005808	ENSPSIP00000009796	C-C motif chemokine ligand 5.	Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family.	0.578
CCL5	LOC102457828	ENSPSIP00000005808	ENSPSIP00000002187	C-C motif chemokine ligand 5.	SCY domain-containing protein.	0.890
CCL5	LOC102458236	ENSPSIP00000005808	ENSPSIP00000004823	C-C motif chemokine ligand 5.	SCY domain-containing protein.	0.707
CCL5	LOC102463449	ENSPSIP00000005808	ENSPSIP00000005787	C-C motif chemokine ligand 5.	C-C motif chemokine.	0.589