28 items (Pelodiscus sinensis) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APPL2	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (643 aa)
	CD6	CD6 molecule. (608 aa)
	IL1RAPL2	Interleukin 1 receptor accessory protein like 2. (658 aa)
	IL17RA	Interleukin 17 receptor A. (810 aa)
	ABCD2	ATP binding cassette subfamily D member 2. (738 aa)
	LOC102459066	Uncharacterized protein. (196 aa)
	APOD	Apolipoprotein D; Belongs to the calycin superfamily. Lipocalin family. (188 aa)
	IL1R2	Interleukin 1 receptor type 2. (424 aa)
	PDCD4	Programmed cell death 4. (468 aa)
	STAT3	Signal transducer and activator of transcription. (707 aa)
	NLRC3	NLR family CARD domain containing 3. (1063 aa)
	PLA2G10	Phospholipase A(2). (143 aa)
	PPARA	Peroxisome proliferator activated receptor alpha. (468 aa)
	LOC102463517	Uncharacterized protein. (435 aa)
	F2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (611 aa)
	TNF	Tumor necrosis factor. (229 aa)
	K7FGU4_PELSI	Uncharacterized protein. (196 aa)
	APPL1	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (708 aa)
	K7FK04_PELSI	Uncharacterized protein. (171 aa)
	K7FL34_PELSI	Uncharacterized protein. (170 aa)
	MYD88	MYD88 innate immune signal transduction adaptor. (186 aa)
	PLD3	Phospholipase D family member 3. (406 aa)
	CUEDC2	CUE domain containing 2. (276 aa)
	ZC3H12A	Zinc finger CCCH-type containing 12A. (573 aa)
	PLD4	Phospholipase D family member 4. (417 aa)
	CARD9	Caspase recruitment domain family member 9. (587 aa)
	IL6	Interleukin 6. (211 aa)
	LOC102450450	Phospholipase A(2). (156 aa)

Your Current Organism:

Pelodiscus sinensis

NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APPL1	APPL2	ENSPSIP00000007726	ENSPSIP00000018146	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	0.995
APPL2	APPL1	ENSPSIP00000018146	ENSPSIP00000007726	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.	Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.	0.995
CARD9	MYD88	ENSPSIP00000010898	ENSPSIP00000008979	Caspase recruitment domain family member 9.	MYD88 innate immune signal transduction adaptor.	0.532
F2	IL6	ENSPSIP00000005404	ENSPSIP00000011060	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Interleukin 6.	0.530
IL17RA	K7FK04_PELSI	ENSPSIP00000012383	ENSPSIP00000008364	Interleukin 17 receptor A.	Uncharacterized protein.	0.975
IL17RA	K7FL34_PELSI	ENSPSIP00000012383	ENSPSIP00000008744	Interleukin 17 receptor A.	Uncharacterized protein.	0.981
IL6	F2	ENSPSIP00000011060	ENSPSIP00000005404	Interleukin 6.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.530
IL6	K7FK04_PELSI	ENSPSIP00000011060	ENSPSIP00000008364	Interleukin 6.	Uncharacterized protein.	0.681
IL6	K7FL34_PELSI	ENSPSIP00000011060	ENSPSIP00000008744	Interleukin 6.	Uncharacterized protein.	0.595
IL6	MYD88	ENSPSIP00000011060	ENSPSIP00000008979	Interleukin 6.	MYD88 innate immune signal transduction adaptor.	0.630
IL6	STAT3	ENSPSIP00000011060	ENSPSIP00000018063	Interleukin 6.	Signal transducer and activator of transcription.	0.881
IL6	TNF	ENSPSIP00000011060	ENSPSIP00000005437	Interleukin 6.	Tumor necrosis factor.	0.591
K7FGU4_PELSI	LOC102459066	ENSPSIP00000007254	ENSPSIP00000015277	Uncharacterized protein.	Uncharacterized protein.	0.562
K7FGU4_PELSI	MYD88	ENSPSIP00000007254	ENSPSIP00000008979	Uncharacterized protein.	MYD88 innate immune signal transduction adaptor.	0.405
K7FK04_PELSI	IL17RA	ENSPSIP00000008364	ENSPSIP00000012383	Uncharacterized protein.	Interleukin 17 receptor A.	0.975
K7FK04_PELSI	IL6	ENSPSIP00000008364	ENSPSIP00000011060	Uncharacterized protein.	Interleukin 6.	0.681
K7FK04_PELSI	K7FL34_PELSI	ENSPSIP00000008364	ENSPSIP00000008744	Uncharacterized protein.	Uncharacterized protein.	0.990
K7FK04_PELSI	MYD88	ENSPSIP00000008364	ENSPSIP00000008979	Uncharacterized protein.	MYD88 innate immune signal transduction adaptor.	0.475
K7FK04_PELSI	STAT3	ENSPSIP00000008364	ENSPSIP00000018063	Uncharacterized protein.	Signal transducer and activator of transcription.	0.626
K7FL34_PELSI	IL17RA	ENSPSIP00000008744	ENSPSIP00000012383	Uncharacterized protein.	Interleukin 17 receptor A.	0.981