STRINGSTRING
ATG101 ATG101 ATG5 ATG5 C16orf70 C16orf70 ULK1 ULK1 ATG14 ATG14 WDR45B WDR45B ATG2B ATG2B ATG7 ATG7 LOC102450218 LOC102450218 ATG2A ATG2A ULK2 ULK2 WIPI1 WIPI1 WIPI2 WIPI2 LOC102456425 LOC102456425
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATG101Autophagy related 101. (230 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (276 aa)
C16orf70Chromosome 16 open reading frame 70. (423 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1030 aa)
ATG14Autophagy related 14. (393 aa)
WDR45BWD repeat domain 45B. (335 aa)
ATG2BAutophagy related 2B. (2079 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (661 aa)
LOC102450218Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (273 aa)
ATG2AAutophagy related 2A. (2002 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1015 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (422 aa)
WIPI2WD repeat domain, phosphoinositide interacting 2. (414 aa)
LOC102456425Protein kinase domain-containing protein. (318 aa)
Your Current Organism:
Pelodiscus sinensis
NCBI taxonomy Id: 13735
Other names: Chinese soft-shelled turtle, Chinese softshell turtle, P. sinensis, Trionyx sinensis, ZMB 38
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